Life Science Research Professional 1

The Mourrain Lab, within the Department of Psychiatry & Behavioral Sciences at Stanford University’s School of Medicine, is seeking a full time Life Science Research Professional 1 (LSRP 1) to study sleep and its effects on neurobiology. The Mourrain Lab specializes in neuroscience, genetics, epigenetics, developmental biology, and engineering to achieve the following objectives: Investigate the reasons behind sleep and how it enhances cognitive performance by altering synaptic connections. Identify and address synaptic deficits observed in neurodevelopmental conditions like Fragile X syndrome, Autism, neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and age-related synaptic changes. Study genes and processes essential for neuronal regeneration to repair damaged brain tissue, including the retina. Enhance knowledge of gene regulation mechanisms and explore the impact of non-coding Single Nucleotide Polymorphisms (SNPs) on causing human diseases. The LSRP 1 will test the impact of sleep disruptions and sleep interventions on autophagosomal activity and cellular redox homeostasis mechanisms.The LSRP will perform CRISPR/Cas9 editing of genes involved in lysosomal and phagosome activity. They will perform molecular analysis of the generated mutations and biochemical phenotyping.

DESIRED QUALIFICATIONS

Bachelor’s degree in Molecular Biology, Biochemisty or related field or MSc desired Prior experience performing biology/gene editing, biochemistry related to oxidative stress, and animal biology. Responsibilities Core Duties : Plan approach to experiments in support of research projects inlab and/or field based on knowledge of scientific theory. Independently conduct experiments; maintain detailed records ofexperiments and outcomes. Apply the theories and methods of a life science discipline tointerpret and perform analyses of experiment results; offer suggestionsregarding modifications to procedures and protocols in collaborationwith senior researcher. Review literature on an ongoing basis to remain current with newprocedures and apply learnings to related research. Contribute to publication of findings as needed. Participate inthe preparation of written documents, including procedures,presentations, and proposals. Help with general lab maintenance as needed; maintain lab stock,manage chemical inventory and safety records, and provide general labsupport as needed. Assist with orientation and training of new staff or students onlab procedures or techniques. Bachelor's degree in related scientific field. Knowledge, Skills and Abilities : General understanding of scientific principles. Demonstratedperformance to use knowledge and skills when needed. Demonstrated ability to apply theoretical knowledge of scienceprincipals to problem solve work. Ability to maintain detailed records of experiments andoutcomes. General computer skills and ability to quickly learn and mastercomputer programs, databases, and scientific applications. Ability to work under deadlines with general guidance. Excellent organizational skills and demonstrated ability toaccurately complete detailed work. Pay Frequency Hourly Fixed Term N Stanford Schools and Units School of Medicine Full time or Part time Full Time Regular or Temporary Regular Job Category Research Grade E Benefits that support you, and your future 18+ PTO days per year Health benefits start when you start Flexible work options $6000+ annual tuition and training assistance 403(b) plan Mental health and wellness programs Free and discounted commuter transportation Applies to regular full-time positions. Notice to Applicants The job duties listed are typical examples of work performed by positions in this job classifications and are not designed to contain or be interpreted as a comprehensive inventory of all duties, tasks and responsibilities. Specific duties and responsibilities may vary depending on department or program needs without changing the general nature and scope of the job or level of responsibility. Employees may also perform other duties as assigned. Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of their job. Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stanford University provides job pay ranges representing its good faith estimate of what the university reasonably expects to pay for a particular job. The specific pay offered to a selected candidate will be determined based on a wide range of factors that are unique to each candidate, including but not limited to geographic work location, relevant knowledge, skills and abilities, relevant education, years of relevant experience, depth and breadth of relevant experience, and performance; further including but not limited to other business and organization needs such as the scope and responsibilities of the position, the minimum qualifications, departmental budget availability, and market and internal equity across the university, school/ unit, department, as well as job reporting relations hips. Why work at Stanford World-changing work in a culture of continuous learning An inspiring community that values collaboration High-quality health and wellness benefits that put you and your family first Access to world-class education and career development, with tuition reimbursement, training assistance, and more #J-18808-Ljbffr Stanford University