Scientist III, Immunology & Flow Cytometry
IBT Bioservices
IBT Bioservices is seeking an experienced, independent, and highly technical Scientist III to join our expanding immunology team. The ideal candidate will serve as a key subject matter expert in advanced flow cytometry and assay development within a fast-paced, high-volume Contract Research Organization (CRO) environment. In this role, you will be responsible for end-to-end execution of complex immunological studies, from tissue processing to high-parameter data analysis. You must be adept at troubleshooting, panel design, and the rigorous validation of assays in compliance with project requirements. Key Responsibilities Flow Cytometry Expertise: Serve as the lead operator for the BD FACSymphony A2 (or equivalent). Perform routine machine maintenance, calibration, quality control, and troubleshooting to ensure optimal performance. Design and validate complex 17+ color panels tailored to specific research objectives. Independently perform mouse tissue harvests, including spleen and lung processing. Execute flow cytometry experiments for diverse sample types, including human, non-human primate (NHP), and murine models. Assay Development & Sample Testing: Participate in development, optimization, and qualification of robust viral or immunology-based assays, ensuring full adherence to internal quality standards, GXP-guidelines, and aggressive client timelines. Proactively troubleshoot assay performance issues to guarantee high data integrity and consistency in a high-volume, fast-paced environment. Demonstrate exceptional pipetting precision and consistency, with the proven ability to handle high-throughput demands—specifically the capacity to execute 50+ 96-well plates per week while maintaining tight Coefficient of Variation (CV) targets. Apply a deep understanding of XLFit (or similar), standard curve analysis and assay linearity to validate performance and ensure reliable quantitative results. Technical Support & Documentation: Maintain detailed batch records and prepare technical reports summarizing findings. Collaborate with cross-functional teams to align on study protocols and data interpretation. Qualifications & Requirements Education: PhD in Immunology, Cell Biology, Microbiology, or a related scientific discipline. Experience: Minimum of 4–6 years of professional experience in a high-volume environment, CRO preferred. Authorization to work in US and Maryland residency. Technical Skills: Hands-on experience with high-parameter flow cytometry (specifically BD Symphony or similar platforms). Demonstrated capability in advanced panel design and multi-color compensation. Strong background in assay development and qualification methodologies. 3+ years of experience on BD Symphony A2 or similar (13+ color). Preferred Skills: Basic operational knowledge or experience with qPCR and ELISPOT techniques is a plus. Soft Skills: Highly independent professional, with proven proficiency in maintaining meticulous, audit-ready documentation in a fast-paced, high-volume setting. Ability to manage multiple concurrent projects with rigorous attention to detail. Strong communication skills, capable of relaying (written and oral) technical data to internal and external stakeholders. #J-18808-Ljbffr IBT Bioservices
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