Research Scientist, Lentiviral Vector Purification and Analytics

The Lentiviral Vector (LVV) Team in the Biologics Research Center (BRC) at Novartis, Cambridge, MA is seeking a highly motivated Research Scientist with experience in production and purification of viral vectors to join our team. This role is a lab‑based position focused on lentiviral vector purification and analytics. It plays a key part in advancing our Cell and Gene Therapy initiatives and contributing to groundbreaking research in CAR‑T cell therapy. The position is based in Cambridge, MA (USA) and does not include relocation support. As a Research Scientist, you will apply hands‑on laboratory expertise to help develop, optimize, and characterize viral vector processes that support next‑generation CAR‑T programs. Opportunities include working across purification and analytical workflows and advancing high‑quality research materials that enable transformative therapeutic approaches. Key responsibilities Execute lentiviral vector purification activities including clarification, chromatography, and TFF. Perform analytical methods (molecular- and cell-based) to assess quality of the purified vector. Write and review protocols, technical reports, and technology transfer documents, providing conclusions and recommendations. Develop and maintain SOPs, instrument procedures, and other laboratory documentation. Plan and prioritize work to meet goals while managing multiple research activities. Support experimental design, data analysis, and troubleshooting. Identify root causes, implement solutions, and verify effectiveness. Present scientific data and contribute openly to discussions. Document experimental procedures and processes thoroughly. Collaborate across teams, share knowledge, and train team members in technical areas as needed. Essential Requirements BS or MS in bioengineering, virology, or a related field with relevant laboratory experience (this is not a PhD-level position). 1–3 years of experience in protein and/or viral vector purification. Hands‑on experience with chromatography and filtration techniques, including TFF and depth filtration. Strong coordination, communication, collaboration, learning agility, and self‑motivation. Proficiency with Word, Excel, PowerPoint, and GraphPad Prism. Excellent oral, written, and interpersonal communication skills. Desirable Requirements BSL2 experience with AAV, lentiviral, or retroviral vector production. Proficiency in aseptic technique, cell culture, molecular biology, and analytical testing. Bioreactor experience. The salary for this position ranges between $66,800 and $124,000 per year for Research Scientist I, and between $81,200 and $150,800 per year for Research Scientist II. The final salary offered is determined based on relevant skills and experience, and will be reviewed periodically. A performance-based cash incentive and, depending on the level of the role, eligibility for annual equity awards are included. US-based eligible employees receive a comprehensive benefits package that includes health, life, and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. Employees are also eligible for a generous time‑off package, including vacation, personal days, holidays, and other leaves. #J-18808-Ljbffr