Sr Associate Scientist I or II, GPCR Biology

Job Summary We are seeking a highly motivated and experienced Senior Associate Scientist I/II to join the GPCR Biology group and advance our core mission of accelerating small molecule drug discovery programs at Iambic Therapeutics. The successful candidate will have a proven track record of supporting in vitro cell-based assays to advance pre-clinical projects. The candidate will work closely with a cross-functional team that integrates machine learning, medicinal chemistry, analytical technology and biology to revolutionize small-molecule therapeutics design and discovery. This role is based at our San Diego headquarters. Key Responsibilities Work closely with the Biology group to independently conceptualize, design and conduct in vitro studies aimed at supporting hit to lead medicinal chemistry efforts targeting GPCRs Independently manage CRO scientists in the design, development, and implementation of in vitro assays for the advancement of GPCR projects Execute weekly cell-based assays to screen/evaluate small molecule compounds in coordination with Biology, Chemistry, and Compound Management groups Interpret and analyze scientific data and work with cross functional teams to QC/communicate data in a timely manner Present experimental results/updates at team meetings Contribute to the management of the biology laboratory Qualifications Bachelor’s or master’s degree in biochemistry, pharmacology, cell biology, or other related scientific areas with a minimum of 3-5 years of industry experience Hands-on experience with traditional and innovative screening methodologies for GPCRs, as well as concepts related to GPCR signaling and trafficking highly preferred Demonstrated scientific rigor with proven ability to critically evaluate data, and think independently and creatively in developing and testing new scientific hypotheses Hands-on experience in cell biology and routine biological assays, including cell culture, HTRF and reporter gene cell-signaling assays, and imaging assays Familiarity with HTS screening methodology is highly desirable Excellent oral and written communication skills is required Highly motivated to work in a cross-functional team setting Flexibility and ability to quickly learn new skills and knowledge on the job Experience with design and implementation of in vivo models in coordination with CROs is highly desirable Pay and Benefits We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play. Compensation $84K - $120K Multiple Ranges #J-18808-Ljbffr Dormont Manufacturing Co