Principal / Senior Scientist, Immunology

Job Overview Janux Therapeutics is seeking a highly motivated Principal Scientist with demonstrated skills in the field of cancer immunology and/or immune cell biology. The incumbent will develop and troubleshoot cell-based assays for pre‑clinical programs. These studies will aid in better understanding of MoA and in differentiation from competition. This person will mentor or manage more junior members in the immunology team, as well as interact closely with members across functional teams. A successful candidate will have extensive hands‑on experience with assay development and troubleshooting, lead the immunology team in laboratory research to ensure timelines are met, inspire and develop team members, and be accountable for meeting deliverables for the Immunology team. This position is approximately 30‑50% hands‑on bench work and requires effective communication and documentation. The ideal applicant will be collaborative and team‑oriented, self‑motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence. Qualifications A PhD in a scientific discipline is common with a minimum of 4+ years related experience; or postdoc experience with 2+ years relevant industry experience; BS with minimum 12+ years; MS with minimum 10+ years experience. Hands‑on experience with development of multi‑parameter flow cytometry (10+ colors) assays. Proficiency in culture of primary human immune cells (ie. PBMCs) is required. Proficiency in flow analysis is required (ie. FlowJo, DIVA, FCS Express, CellEngine, or Cytobank). Proficiency in Excel, PowerPoint and GraphPad Prism is required. Excellent oral and written communication skills. Ability to influence others with or without direct authority. Experience working with external vendors is a plus. Effective troubleshooting and problem‑solving skills. Success in this role requires great attention to detail with the ability to multitask. Skills to be an effective team player, strong individual contributor, self‑motivated, flexible, and able to handle multiple tasks and deliver high‑quality results under tight timelines. Strong organizational skills and related diligence with documentation is required. Compensation & Benefits Base salary range: $145,000 – $174,000 per year (guideline, actual variation based on qualifications and location). In addition to salary, we offer stock options, restricted stock units, a stock purchase plan (ESPP), and a target bonus. Janux provides a comprehensive benefits package including medical, dental, vision, and supplemental disability insurance. Annual bonus program Incentive stock option plan 401(k) plan with flat non‑elective employer contribution Comprehensive medical insurance with 90‑100% employer‑paid premiums Dental and vision insurance HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity) Unlimited PTO Generous holiday schedule; includes summer and winter company shutdown Relocation assistance Job Details Job Type: Full‑time Schedule: Monday to Friday Work Location: On site (San Diego, CA) Work Authorization: United States (Required) EQUAL OPPORTUNITY EMPLOYER Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity. #J-18808-Ljbffr