Principal PK/PD Modeling Scientist - Translational Analytics
Amgen Inc. (IR)
Amgen Inc. (IR) is seeking a Principal Scientist in South San Francisco, CA. This pivotal role contributes to drug discovery by focusing on pharmacokinetics and pharmacodynamics of drug candidates. Responsibilities include applying mathematical modeling and collaborating with cross-functional teams to support drug development decisions. The ideal candidate possesses a Doctorate degree or equivalent experience in quantitative PKPD principles and has proven skills in systems modeling. A comprehensive benefits package and flexible work models are included. #J-18808-Ljbffr Amgen Inc. (IR)
$163.67k - $221.44k
...Category: Scientific Position Title Principal Scientist‑PKDM, Modeling and Simulation What you will do In... ...response relationships, execution of translational strategies, and influencing... ...fit‑for‑purpose mathematical models (PK‑PD, QSP, PBPK) using specialized relevant...PrincipalFlexible hours- Principal Scientist Computational Biology & Translational AI (Oncology Precision Medicine) Join Amgen's Mission of Serving... ...designing and deploying AI‑enabled analytical and agentic systems that connect... ...literature) using AI‑enabled or model‑based approaches. Strong...PrincipalRemote workFlexible hours
- ...patients while transforming your career. Senior Scientist - Computational Discovery & Translational Analytics What you will do Lets do this. Lets change the world... ...advancements in digital technologies for disease modeling and digital modality engineering to accelerate...SuggestedFlexible hours
$163k - $193k
...while transforming your career. Principal Scientist - Clinical Pharmacology, Modeling & Simulation What you will do... ...and simulation strategies for translational approaches to support clinical... ...Pharmacokinetic/Pharmacodynamic (PK/PD) modeling, Mechanistic-Physiologically...PrincipalRemote workWork from homeFlexible hours$120k - $140k
Parvus Therapeutics, Inc. in South San Francisco is hiring an Associate Scientist to drive preclinical PK/PD projects and develop models for their clinical pipeline. Candidates should have 6+ years of experience in Immunology (8+ for Bachelor's) and expertise in animal...Suggested$124.3k - $230.9k
...are seeking a highly motivated Senior Scientist or Principal Scientist with a strong record of... ...depth to join our Synthetic Molecule Analytical Chemistry (SMAC) group. This role is... ...Working knowledge of data analysis, modeling, and AI assisted workflows, including...PrincipalLocal areaRelocation package- ...Job Description Job Description Principal Scientist / Senior Scientist, Analytical Chemistry (Biopolymers) Location: Brisbane, CA (Onsite) About... ...design, formulation, and preclinical science to translate platform innovation into a pipeline of transformative...Principal
$167.4k - $310.8k
...data and novel computational models to drive impact. Seamless... ...Intelligence (AI) to assist our scientists in both pRED and gRED to... ...We are seeking a Senior or Principal Machine Learning Scientist to... ...complex decision‑making. Domain Translation: Translate biological and...PrincipalLocal areaWorldwideRelocation package$235.5k - $329.5k
...for an experienced Sr. Director of Clinical Pharmacology and Translational PK/PD to lead the technical and operational aspects of the... ...through market authorization Select and execute appropriate modeling and simulation approaches (PK/PD, PopPK, exposure-response)...Full timeWork at officeWork visa3 days per week$140k - $250k
Principal Scientist, Protein Sciences, Analytical Characterizations September 2025 Department: Technology Position Summary... ...with a clear orientation toward translating findings to deliver therapeutic... ...novel ‘venture capital-biotech’ model. Our core mission is to...PrincipalFull timeTemporary workFlexible hours$124.3k - $230.9k
Senior Scientist / Principal Scientist - Synthetic Molecule Analytical Chemistry We are seeking an experienced scientist with a strong record of laboratory innovation... ...strategies. Working knowledge of data analysis, modeling, and AI‑assisted workflows including effective...PrincipalLocal areaRelocation package- ...clinical, pharmacological and translational research and development... ...biologyWorks with TM laboratory scientists and academic TLs to address... ...eligible for a hybrid work model with at least 50% onsite at... ...with Ripley.R1600104 : Senior Principal Scientist, Cardiovascular,...PrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work
- ...transforming your career. Principal Scientist - PKDM (Large Molecule Project... .../pharmacodynamic (PK/PD) properties of biologic therapeutics... ...Designing and executing translational PK/PD and mechanistic ADME... ...time-off plans Flexible work models where possible. Refer to...PrincipalFlexible hours
$160.06k - $193.95k
...working-with-us. Position Summary Translational Development is part of the... ...Works with TM laboratory scientists and academic TLs to address... ...eligible for a hybrid work model with at least 50% onsite at... ...with Ripley. R1601688 : Senior Principal Scientist, Neuroscience,...PrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$177k - $308k
...companies access to drug discovery models trained on years of Lilly's... ...models across key ADMET and PK/PD endpoints — including... ...and designed for partner use. Translational Modeling: Develop translational... ...: Provide coaching to junior scientists and contribute to TuneLab's growing...Full timeFlexible hours$159.6k - $251.2k
...We are seeking an Associate Principal Scientist with strong expertise in respiratory biology and translational research to contribute to target... ...and apply human-relevant model systems (e.g., primary airway... ...patient stratification, and PK/PD relationships Experience in an...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$268k - $384k
...Senior / Principal ML Scientist, Foundation Models for Life Sciences San Francisco, CA USA Your Impact at LILA Lila is building a platform where... ...experimental results improve model performance Translate complex biological questions into well-defined ML problems...PrincipalFull timeWork at officeLocal areaFlexible hours$286.9k
...Senior Principal Scientist (Senior Medical Director) Translational Medicine, Immunology Translational Medicine in our Research & Development Division is responsible... ...with scientific, regulatory, statistical, and modeling colleagues across the organization to translate...PrincipalWorldwide$150.7k - $279.9k
...causal disease biology and translate it into actionable targets,... ...Opportunity We are seeking a Principal Scientist (Bioinformatics track) to lead... ...and robust benchmarking) so model outputs are decision‑ready... ...developing and scaling reusable analytics pipelines, platforms, or...PrincipalLocal areaRelocation package$124.3k - $230.9k
Overview We are seeking a highly motivated Senior Scientist or Principal Scientist with a strong record of laboratory innovation and technical depth to join our Synthetic Molecule Analytical Chemistry (SMAC) group. The successful candidate will thrive at the bench and...PrincipalLocal areaRelocation package- ...ML Research Scientist, Foundation Models About the Team Join a world-class team at the forefront... ...of seniority: Senior, Staff, and Principal. You will Lead transformative... ...with a multidisciplinary team to translate your research into tangible impact on...PrincipalTemporary work
$160k - $200k
...Senior Scientist/Principal Scientist, DMPK Tenvie is a biotechnology... ...Key deliverables are human PK and efficacious dose predictions... ...risk assessment based on translating in vitro and nonclinical data... ...and implementing PK and PK/PD modeling and simulation and...PrincipalFull timeLocal area- ...transforming your career. Senior Scientist - LCMS What you will do Let... ..., and implement emerging analytical technologies to support... ...data in the context of PK/PD, translational biomarkers, target biology,... ...time‑off plans Flexible work models where possible. Refer to the...Flexible hours
$125k - $180k
Clinical Development Scientist/Senior Clinical Development Scientist... ...design who are motivated to translate biology into impactful... ...Pharmacology on endpoint hierarchy, PK/PD modeling plans, and interim analyses... ...‑paced environment Strong analytical and critical‑thinking skills...Interim roleLocal areaRemote work$177k - $197k
...harness advanced technologies and model systems to increase our... ...a highly skilled in vivo scientist to significantly advance neurodegenerative... .... This will enhance the Translational Neuroscience team's in vivo... ..., and image analysis * Analytical & Communication Skills: *...Full time$197k - $245k
...is to harness advanced technologies and model systems to increase our understanding of... ...knowledge, and the ability to translate laboratory findings into robust processes... ...analysis using, HPLC, GC, LC-MS, and other analytical techniques * Perform impurity identification...PrincipalFull timeContract workShift work$159.6k - $251.2k
...and accomplished Associate Principal Scientist to join our Quantitative... ...strategy and pharmacodynamics (PD) and efficacy models for cardiometabolic, renal... ...establishing quantitative PK/PD relationship and... ...individual will apply knowledge of translational animal models, in vivo...PrincipalFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work$168.6k - $313k
...experienced Medicinal Chemist (Senior Principal Scientist) to join our innovative research and development... ...and interpretation of complex analytical data, including mass spectrometry,... ...Methods: Experience with computational modeling and simulation for peptide design and...PrincipalLocal areaRelocation package$143.2k - $265.9k
...seeking a creative and highly motivated Principal Scientist, Medicinal Chemist to join our R&D... ...macrocyclization or ligation strategies. Analytical Rigor: Personally oversee high-... ...structure-based design, and computational modeling (e.g., MD simulations) to optimize potency...PrincipalLocal areaRelocation package- Amgen SA in South San Francisco seeks a Principal Scientist to lead pharmacokinetics and drug metabolism projects for large molecules. This... ...development. The role offers competitive compensation, flexible work models, and a comprehensive benefits package, ensuring personal and...Flexible hours
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