Principal Clinical Study Manager

Stryker is seeking a Principal Clinical Study Manager to join our Neurovascular Division. This is a remote position based anywhere within the United States.

As the Principal Clinical Study Manager , you will lead the planning and execution of complex clinical studies that advance innovation in stroke care. You will collaborate with cross-functional teams, ensure compliance with regulatory standards, and drive operational excellence to deliver high-quality results.

What You Need

• Lead cross-functional clinical project teams, setting study strategy, timelines, budgets, and performance expectations across multiple global trials.

• Design and develop clinical study protocols and investigational plans in collaboration with physician advisors and internal stakeholders.

• Ensure compliant execution of clinical studies aligned with IRB/EC requirements, global regulatory standards, and company policies.

• Own end-to-end study management, including budget development, cost control, and delivery of high-quality, ethical, and publishable results.

• Oversee site selection, qualification, monitoring, and close-out, while directing CRAs and resolving operational and site-level issues.

• Drive study start-up and execution activities, including contracts, site training, CRF design, data management coordination, and CRO oversight.

• Monitor study performance through metrics and reporting, implementing corrective actions and maintaining clear communication with sites and stakeholders.

• Support regulatory submissions (e.g., IDEs, amendments) and lead study reporting, from progress updates through final reports and publication.

Required

• Bachelor's degree in science or health care related field

• 8+ years of relevant work experience in clinical research with minimum 4 years of clinical study management experience

• Experience in the Medical Device or Pharmaceutical industry

• Proven ability to manage complex study programs, budgets, schedules, and cross-functional teams

• Strong leadership, communication, and stakeholder management skills

Preferred

• CCRP, ACRP, PMP, PgMP, or equivalent professional certification

• Experience leading cross-functional teams

Posting Date: 06/02/2026

Posted Date: 06/02/2026
This role will be posted for a minimum of 3 days.

United States of America Pay Ranges:

• USN : $118,000 - $196,700 USD Annual
• US5 : $123,900 - $206,500 USD Annual
• US10 : $129,800 - $216,400 USD Annual
• US15 : $135,700 - $226,200 USD Annual
• US20 : $141,600 - $236,000 USD Annual
• US30 : $153,400 - $255,700 USD Annual

View the U.S. work location and transparency guide to find the pay range for your location.