Molecular Biologist

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Title-Bench Scientist - II(DNA Production)

Location-Cambridge,MA,USA,02140

Duration- 2 years contract

Role Summary

• BioMedicine Design (BMD) is seeking a highly motivated Biochemist/ Molecular Biologist to join Biotherapeutic Expression and Purification group (BEP) in Cambridge, MA. Qualified candidate will play an essential role in a high-energy DNA production and protein expression research laboratory.
• The group supports non-GMP transient protein lead production across diverse biotherapeutic discovery portfolio to enable research units and their pre-clinical therapeutic in-vitro and in-vivo needs.
• The BEP DNA production and protein expression group is looking for a laboratory technician to provide DNA production support for the protein expression and purification activities in BEP.
• The candidate is expected to have a strong background in molecular biology techniques and experience with nucleic acid production and analysis .
• The successful candidate will grow bacterial cultures and perform large-scale DNA production activities following standardized protocols.
• The candidate will be a key contributor to the scientific team responsible for
• protein expression and purification.

Role Responsibilities

• Independently execute high-throughput plasmid DNA production workflows including bacterial culture, plasmid purification , and downstream sample handling
• Operate and troubleshoot automated instrumentation including Biotage, Opentrons, and related liquid handling platforms
• Perform DNA quality control testing including gel electrophoresis, nucleic acid quantification, purity assessment, and endotoxin testing
• Prepare and submit samples for next-generation sequencing (NGS) and support basic data review of sequencing results
• Manage plasmid DNA inventory, sample storage, and tracking within electronic databases and sample management systems
• Maintain accurate records in an electronic lab notebook and ensure documentation compliance
• Collaborate with expression and purification scientists to ensure timely DNA delivery for downstream workflows
• Contribute to process improvements to enhance throughput, reproducibility, and cycle time
• Communicate progress, priorities, and risks to meet production schedules and deadlines

Qualifications Education

• B.S. in Biological Sciences, Molecular Biology, Biotechnology, Biochemistry, or a related life sciences discipline

Required

• 2+ years experience with molecular biology techniques including plasmid preparation, nucleic acid purification, and quantitative DNA analysis
• 2+ years experience with bacterial cell culture systems
• Proficiency in DNA QC methods including gel electrophoresis and sample preparation for sequencing
• Experience operating automated or semi-automated lab instrumentation
• Strong organizational skills with the ability to manage multiple projects in a high-throughput setting
• Proficiency with electronic lab notebooks and sample tracking systems
• Attention to detail during repetitive, high-volume tasks
• Strong communication and teamwork skills
• Commitment to laboratory safety and compliance

Preferred

• Experience with NGS library preparation or sequencing workflows
• Familiarity with Python scripting for data analysis or workflow automation
• Experience with plate-based (96/384-well) high-throughput workflows
• Familiarity with LIMS or sample management platforms (e.g., FreezerPro, Genedata)

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We believe in more than just jobs—we build careers. At Net2Source, we champion leadership at all levels, celebrate diverse perspectives, and empower you to make an impact. Think work-life balance, professional growth, and a collaborative culture where your ideas matter.

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Net2Source is an equal opportunity employer, dedicated to fostering a workplace where diverse talents and perspectives are valued. We make all employment decisions based on merit, ensuring a culture of respect, fairness, and opportunity for all, regardless of age, gender, ethnicity, disability, or other protected characteristics.

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