Senior Director, US Medical Affairs - Nephrology

General Summary The Senior Director (non-MD) serves as a US Medical Affairs asset lead responsible for strategic planning and execution of launch and lifecycle assets within the Vertex nephrology portfolio. Provides scientific leadership across cross-functional teams to align medical strategies with corporate objectives, patient needs, and the US treatment landscape. Builds and leads a team of Medical Directors and Associate Medical Directors while serving as a trusted scientific partner. Key Duties & Responsibilities Lead development, execution, and refinement of US Medical Affairs strategic/operational plan for assigned asset(s) from pre-launch through lifecycle. Serve as primary internal medical-scientific authority; interpret data and translate into actionable medical strategy. Build trusted relationships with US nephrology thought leaders, academic investigators, and external experts. Partner cross-functionally with Commercial, Market Access, HEOR, Regulatory, Clinical Development, and Corporate Communications for aligned launch readiness. Design and execute medical evidence generation initiatives (e.g., investigator-sponsored research, advisory boards, medical education). Deliver compliant, fair, balanced scientific presentations/communications. Provide medical input into promotional/non-promotional material review (CRC/MLR) to ensure substantiation and compliance. Establish and track medical KPIs; use scenario planning and market foresight. Required Education Terminal doctoral degree (PhD, PharmD, MD, DO, or equivalent). Required Experience 10+ years Medical Affairs/related scientific experience. 3+ years supervisory/people management. Required Knowledge/Skills US medical launch strategy experience. High EQ; relationship building internally/externally. Ability to deliver in a highly matrixed environment. Scientific knowledge of nephrology/immunology/related areas and evidence generation. Strong written/oral communication; influence senior leadership. Analyze complex data and translate to strategy; deliver high-impact projects on timelines. Proactive, organized; manage shifting pre-/launch priorities. Preferred Requirements Prior launch experience in nephrology, immunology, or rare disease. Experience managing/developing Medical Directors/Associate Medical Directors. Nephrology-specific expertise preferred. Pay Range $252,000 - $378,000. #J-18808-Ljbffr