Senior Research Technologist - Lucas-McAllister Lab

This is an exciting opportunity for an energetic, ambitious, and creative individual to help shape the future of a discovery-oriented biomedical research laboratory. The primary research focus of the lab centers on the interaction of cancer with the immune system. We are searching for an individual to take a major role in operations for this expanding team. The lab is jointly directed by senior Principal Investigators:Dr. Peter Lucas - Vice Chair for Research, Department of Laboratory Medicine and PathologyDr. Linda McAllister - Enterprise Deputy Director, Pediatric Cancer Programs, Mayo Clinic Comprehensive Cancer CenterThe successful candidate will work closely with our group, which includes a Principal Research Technologist, a Senior Program Coordinator Administrative Leader, Senior Research Scientists, Post-Doctoral fellows and PhD Student Trainees.The candidate we seek will:- Support lab member projects via method development, conduction of experiments, data analysis and interpretation- Design and complete experiments geared towards research objectives of the lab- Assist in routine laboratory operations including ordering, regulatory documentation/compliance (chemical safety, biosafety, IACUC and IRBs), personnel training, equipment/reagent management and maintenance- Have strong organizational and record keeping skills, as well as the ability to accurately collect, store and interpret research data- Contribute to manuscript and grant writing- Present at research laboratory meetingsAdditional Job Responsibilities:1. Assists in design of experiments and protocols. Executes experimental studies in support of lab goals.2. Demonstrates a basic understanding of lab practices.3. Performs experiments according to established procedure and under the direction of senior lab personnel.4. Keeps detailed log of experimental procedures.5. Trains lab personnel in lab techniques.6. Maintains equipment and supplies.7. Assists in the selection of instrumentation and computer software and hardware.8. Collects, documents and analyzes data.9. Presents at lab meetings.10. Reports difficulties in experimentation and data collection and follows through with protocol modifications.11. Troubleshoots problems using established or novel experimental procedures.12. Communicates effectively during team meetings about research design and results interpretation.13. Maintains inventory of supplies, chemicals, animals, in a written or electronic format.14. Provides training on the use of instrumentation and methods.15. Maintains governmental laboratory regulations and standards (i.e., IRB, IACUC, OSHA, Bio-safety, etc.).16. Contributes to IACUC or IRB protocols.17. Interacts and negotiates with supply and equipment vendors.18. Prepares graphs, tables and figures for grants and manuscripts.19. Interprets results and reports results to investigators.20. Strives to improve knowledge in appropriate field of research investigation.21. Communicates effectively about projects in teams meetings.22. Attends lectures, seminars and journal clubs to increase knowledge base.23. Reads literature to gain knowledge relevant to current work assignment.Why Mayo Clinic Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. Benefits HighlightsMedical: Multiple plan options.Dental: Delta Dental or reimbursement account for flexible coverage.Vision: Affordable plan with national network.Pre-Tax Savings: HSA and FSAs for eligible expenses.Retirement: Competitive retirement package to secure your future. Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.Equal OpportunityAll qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization. Requires bachelor's degree in biology, chemistry, other relevant science. Preference for candidates with 4 to 6 years of relevant research laboratory experience. Must exhibit a solid understanding of lab techniques, equipment, and safety. Must have the ability to organize and carry out laboratory techniques independently and in a team setting. Must be able to work with a variety of people at all levels both within and outside of the institution. Experience with basic data analysis is required. Skills in bioinformatics considered a plus. This position requires demonstrated writing skills.Note: Visa sponsorship is not available for this position. Must be U.S. citizen, permanent resident, refugee or asylee.Demonstrate ability in these desired skills:Cell Culture and Viral Techniques: Mammalian cell culture, transient transfection, lentiviral/retroviral production, and stable cell line generationProtein Analysis: Western blotting, ELISA, immunohistochemistry (IHC), confocal microscopyMolecular Biology and DNA technologies: qPCR, DNA/RNA preparation, molecular cloning, and plasmid preparationFlow Cytometry: Sample preparation, staining, and basic data acquisition/analysisAnimal Work: Mouse handling, murine tumor modeling, intraperitoneal (IP) injection, and subcutaneous injection**Part of the selection process includes an OnDemand (pre-recorded) interview to complete at your convenience. During that interview, a question will appear on your screen, you will have time to consider each question before responding and have the opportunity to re-record your answer to each question – Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member and you will be notified of next steps.​**Full timePosting Date: 2026-08-12