Postdoctoral researcher

Postdoctoral positions are available to study leukocyte biology and inflammation in the Department of Pharmacology, Yale University School of Medicine, New Haven, CT. My laboratory has been studying various signaling pathways, including Wnt and GPCR‑coupled ones, for their roles in leukocyte functions with emphasis on inflammation, tissue injuries, autoimmune diseases, and tumor immunology. We are using biochemical, molecular, cellular, structural, genomic (including CRISPR/Kas9 screening, single cell sequencing), proteomic, lipidomic, metabolomic, and mouse model approaches. We have made important contributions to characterization of Wnt signaling mechanisms Mol Cell 7, 801; Nat Genet. 37, 945; Science 321, 1350 and their roles in tumor immunity and inflammation Nat Comm 15,3068 & 15,603; Cell Rep 43, 113934; Nat Med 24, 262; Cancer Cell 38, 844, and neutrophil migration and recruitment mechanisms and their roles in inflammatory diseases Cell 187, 846; Sci Transl Med 13, 591; Nature Medicine 22: 1033-42; Cell Report 14,734; Dev Cell 27,215; Nature Cell Biology 4, 686; Dev Cell 21, 1038, Immunity 33, 340, JCI 118, 195, S, Nat Cell Biol. 7, 399, Cell 114, 215, Science 287, 1046. We continue working with increased emphasis on investigation of neutrophil biology in the context of tissue injury, inflammation‑related diseases, and cancer. Competitive salary and an excellent work environment are offered. Self‑motivated individuals with an advanced degree in any area of biomedical sciences are encouraged to apply. #J-18808-Ljbffr