Principal Investigator (MD/DO)

Job Description

Job Description

Internal Medicine Physician — Principal Investigator (Training Provided)

Alliance Clinical Network — Phoenix, AZ | Full - Time or Part-Time | 1099 Independent Contractor

About Alliance Clinical Network

At Alliance Clinical Network, we advance medical innovation through high-quality, patient-centered clinical research. Our culture values compassion, integrity, and operational excellence—so you can focus on great medicine at a sustainable pace.

Role Summary

We’re seeking an Internal Medicine physician (MD/DO) to serve as a Principal Investigator (PI) at our Phoenix research site. This position is ideal for a physician seeking a slower pace of work and very flexible, part-time hours (approximately 5–20 hours/week; typically 10–20 hours/week depending on study needs). Comprehensive PI onboarding and ongoing support are provided. You’ll provide medical oversight for clinical trials, ensure participant safety, and help generate high-quality data—without the heavy demands of a traditional clinic schedule.

Key Responsibilities

• Serve as the study physician for assigned trials; ensure participant safety and ethical conduct.
• Review and confirm participant eligibility; oversee screening outcomes, AEs/SAEs, and retention trends.
• Perform/oversee study-specific medical assessments (histories/physicals, concomitant meds, endpoint review).
• Provide medical oversight to site staff (Sub-Investigators, CRCs, RNs, lab staff); be available for consults and safety questions.
• Collaborate with IRBs, sponsors, and CROs; join SIVs, monitoring visits, and close-out activities as needed.
• Ensure compliance with protocols, site SOPs, ICH-GCP, FDA/21 CFR, and Arizona state requirements.
• Review clinical data (labs, ECGs, vitals) and support timely safety reporting and documentation.
• Contribute to high-quality source documentation, query resolution, and continuous improvement of site processes.

 

  Why This Role Fits a Slower Pace

• Predictable scheduling anchored to study visit calendars (no overnight call; rare urgent escalations).
• Focused patient interactions with pre-screened volunteers and comprehensive study protocols.
• Dedicated research team handles day-to-day coordination; you provide clinical oversight and judgment.
• Flexible hours—work blocks can often be scheduled around your availability.

 

Training & Support

• Structured PI onboarding (GCP/ICH training, protocol-specific training, mentorship from experienced PIs).
• Ongoing support from seasoned clinical operations, regulatory, and QA teams.
• Clear SOPs, templates, and documentation workflows to simplify your transition into research.

 

Qualifications — Required

• MD or DO (Internal Medicine).
• Active, unrestricted Arizona medical license.
• Interest in clinical research and comfort reviewing structured clinical data.
• Strong documentation, communication, and confidentiality practices (HIPAA/PHI).

 

Qualifications — Preferred

• Prior experience as a PI or Sub-Investigator (not required—training provided for the right candidate).
• Familiarity with ICH-GCP and FDA regulations (21 CFR Parts 50, 54, 56, 312, 812).
• Board certification in Internal Medicine; DEA registration if required by specific protocols.

 

Location

On-site at Phoenix, AZ (some remote chart review/sponsor calls as studies permit).

How to Apply

Please send your CV and a brief note of interest (AZ license status, board certification, earliest start date) to our recruiting team. References available upon request.

EEO Statement

Alliance Clinical Network is an Equal Opportunity Employer/Contracting Partner. We celebrate diversity and are committed to an inclusive environment for all clinicians and staff.

Accessibility/Accommodation

If you require a reasonable accommodation to apply or interview, please let us know.

ACN does not provide visa sponsorship for this role. Candidates who will require immigration or visa sponsorship at any time now or in the future (including, but not limited to, H‑1B, TN, or STEM OPT training plans) are not eligible for this role.

About the Company:

At Alliance Clinical Network, our mission is to advance medical research by enrolling diverse populations in high-quality clinical trials. We are committed to maintaining the highest standards of integrity and excellence, and to ensuring that every participant receives respectful and compassionate care. We strive to build a tightly knit, supportive and collaborative environment where our team members can thrive and make meaningful contributions to human health.