Director, Corporate Strategy

Lakefront Biotherapeutics is a global biotech with offices in Belgium, Chicago and San Francisco, focused on building a differentiated immunology and inflammation pipeline to address serious diseases with high unmet medical need. Our pipeline is anchored by T‑cell engager programs, led by a potential first‑in‑class clinical asset and complemented by an exciting preclinical portfolio in autoimmune disease. Our lead asset is being developed for severe immune‑mediated diseases, while additional preclinical programs expand the long‑term potential of our R&D pipeline. At Lakefront, we focus on advancing programs with strong biological rationale, clear clinical proof of concept and large commercial opportunities. Are you ready to transform lives and be part of a journey like no other? We are building a company where science, execution, and accountability matter. Rather than layers of hierarchy, we operate with small, empowered teams that work hands‑on across development stages to move programs forward efficiently and thoughtfully. We are looking for people who want to contribute directly, who are motivated by solving real problems, collaborating across disciplines, and taking ownership from idea to impact. At Lakefront, every role plays a part in shaping the future of medicines that have the potential to make a meaningful difference for patients. If you are driven to improve the lives of patients, energized by execution, and excited to help build a growing company with a strong balance sheet, we look forward to meeting you. THE OPPORTUNITY Lakefront Biotherapeutics is seeking a Director, Corporate Strategy to support the VP, Corporate Strategy in shaping enterprise and portfolio strategy and driving key strategic decision‑making across the company. This role is designed for a high‑impact strategic leader who combines rigorous analysis with strong synthesis, executive communication, and sound judgment in a fast‑moving biotech environment. The Director will play a central role in portfolio planning, evaluation of internal and external opportunities, and preparation of materials for senior leadership and the Board. Working closely with senior stakeholders across Strategy, R&D, Finance, and Business Development, this role ensures that strategic priorities are clearly defined, well‑informed, and effectively communicated. WHAT YOU’LL DO Support development of enterprise and portfolio strategy through structured analysis and synthesis of internal and external inputs Develop frameworks and insights to inform portfolio choices, growth priorities, and capital allocation decisions Prepare decision-ready materials and recommendations on key strategic topics External Landscape & Strategic Insights Identify and synthesize industry trends, competitive developments, and innovation themes Develop enterprise‑level perspectives across therapeutic areas, modalities, and companies Engage with external experts and key opinion leaders to inform strategic assessments Lead deep‑dive strategic projects assessing risks, opportunities, and strategic fit Board & Executive Communication Develop Board-facing materials, strategic updates, and decision memos Translate complex strategic topics into clear, concise executive communication Partner with senior leadership and Investor Relations to communicate strategic direction Cross-functional Collaboration Partner across Strategy, Commercial Assessment, Search & Evaluation, Finance, R&D, and other functions Ensure cross‑functional insights are integrated into strategic recommendations Strategic Integration & Special Projects Support integration of acquired or partnered assets and capabilities Provide analyses and recommendations for integration planning and synergy capture Contribute to high‑priority strategic initiatives as business needs evolve WHAT YOU BRING 8+ years of experience in biopharma corporate strategy, portfolio strategy, corporate development, consulting, or related field Strong understanding of scientific, commercial, strategic, and financial drivers in biotech Advanced degree preferred (MBA, PhD, MD, or equivalent) Strong analytical and strategic thinking capabilities with the ability to structure complex problems Excellent communication skills, including executive‑level presentations and Board materials Ability to balance big‑picture strategy with hands‑on execution High level of ownership, collaboration, and stakeholder management Comfortable operating in a high‑visibility, dynamic environment At Lakefront Biotherapeutics, we are committed to attracting individuals who bring strong expertise, integrity, and a collaborative mindset. We value people who take ownership, work effectively across teams, and want to contribute to meaningful progress. You will join a highly motivated and supportive team working together to advance our pipeline and strengthen how we operate. As we continue to build and grow, we offer an environment where individuals can develop, take on responsibility, and make a tangible impact. Lakefront Biotherapeutics is dedicated to ensuring equal employment opportunities. Our hiring decisions are based on merit, considering qualifications, skills, performance, and achievements. We strictly prohibit discrimination against any employee or job applicant based on personal characteristics that are unrelated to their job. #J-18808-Ljbffr Lakefront Biotherapeutics, Inc.