Senior Manager, Logistics

Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at and follow us on X, LinkedIn and Facebook. Role Summary: The Senior Manager plays a critical role in managing end-to-end logistics operations for both clinical and commercial supply. The role will be responsible for the coordination and oversight of cold chain material movements between Contract Manufacturing Organizations (CMOs), warehouses, and distribution partners. The Senior Manager partners closely with Supply Chain, Quality, Manufacturing, Finance, Commercial, and external partners and stakeholders to ensure seamless logistics operations, supply continuity, compliant flow of materials, as well as clinical study and commercial launch readiness. This is a hands-on operational role with strategic elements focused on day-to-day warehouse and courier management, process improvements, development and maintenance of Standard Operation Procedures (SOP), and readiness for product commercialization. This role is based in Waltham, MA and requires on-site presence. Primary Responsibilities Include: Logistics Operations Coordinate and oversee domestic and international cold chain shipments between Contract Manufacturing Organizations (CMO), warehouses, Third-Party Logistics Providers (3PL) and other supply chain nodes. Serve as the Logistics lead for network re-supply, working closely with internal stakeholders (e.g. Supply Planning, Quality, Manufacturing) and external partners (e.g. couriers, CMOs, customs brokers, warehouses, 3PLs). Ensure timely and compliant execution of shipments, including documentation preparation and review, courier booking, shipment tracking, import/export activities, post-shipment follow-up and closure. Troubleshoot logistics issues and implement corrective actions as needed. Ensure all logistics activities are conducted in compliance with GMP, GDP, and international trade regulations and maintain accurate shipment documentation. Commercial Launch Readiness Support the set up of the 3PL for commercial launches. Collaborate with cross-functional teams to establish processes and capabilities to support ongoing and future commercial operations. Develop, implement and maintain the necessary SOPs and Work Instructions. Stakeholder & Vendor Management Develop and maintain strong, collaborative relationships with internal teams and external stakeholders and partners. Monitor courier, warehouse and 3PL performance and drive improvements. Act as logistics liaison in cross-functional and partner meetings to ensure alignment and proactive communication. Education and Skills Requirements: Bachelor’s degree in Supply Chain Management, Logistics, Life Sciences, or a related field. Advanced degree or certification (e.g., APICS, IATA, SCPro) is a plus. Minimum of 6 years of experience in supply chain, logistics, or trade compliance within biotechnology, pharmaceuticals, healthcare, or another regulated industry. Strong operational experience managing material movements across CMOs, 3PLs, and warehouses within a global network. Experience supporting clinical and/or commercial supply chains, including launch activities and building distribution infrastructure. Working knowledge of GMP/GDP standards, cold chain logistics, and international shipping regulations. Solid knowledge of customs clearance processes and import/export regulations. Experience with logistics systems (e.g., Oracle, SAP) preferred. Strong communication and interpersonal skills. Highly collaborative and proactive problem solver with the ability to operate independently in a fast-paced environment. High attention to detail and organizational skills. Ability to manage multiple priorities and stakeholders simultaneously. LI-Onsite MA Pay Range

$140,000—$170,000 USD

The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.