Senior Director, US Rare Disease Value and Access

Job title: Senior Director, US Rare Disease Value and Access Location: Cambridge, MA About the Job Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. As Senior Director, US Rare Disease Value and Access within our US Rare Disease Leadership Team, you’ll own payer‑focused access strategy across a $2.2B business with 7 marketed products and 2 pipeline launches, including a landmark AATD therapy in 1H 2027. You’ll lead pricing, contracting, reimbursement, and GTN strategy to maximize formulary adoption and patient access. This role is a member of the US Leadership Team and reports directly to the General Manager. You’ll be joining Sanofi’s US Rare Disease business at a pivotal moment, managing market access for a portfolio with a clear growth trajectory to $3.1B by 2030, leading payer strategy for breakthrough therapies, and ensuring patients can access innovative treatments without delay. Main Responsibilities Partner with GM and senior leadership to set direction for pricing, contracting, GTN, and reimbursement across the rare disease portfolio Develop evidence‑based market access strategies that maximize formulary adoption and patient access Create compelling value propositions for payers, providers, and key stakeholders Oversee and optimize GTN across the therapeutic area, pricing, rebates, and discounts by channel Monitor GTN performance and deliver recommendations to senior leadership to protect profitability Collaborate with Finance, Forecasting, Trade, Legal, and Patient Support Services to improve net sales Lead GTN pull‑through across all channels and geographies based on formulary position Anticipate changes in regulatory and reimbursement landscape; ensure sustained compliance and access Develop primary payer research and advisory board programs to close market access knowledge gaps Champion launch readiness for landmark AATD therapy (1H 2027) across payer, access, and reimbursement dimensions Monitor competitive landscape and payer behavior in partnership with Business Insights & Solutions Define KPIs and track progress against access and financial targets Balance brand objectives and patient access priorities when they conflict Build, develop, and lead a high‑performing team of 2 direct reports About You The Senior Director, US Rare Disease Value and Access owns the value, evidence, pricing, and reimbursement strategy that turns an approved rare disease therapy into a covered, affordable, and accessible one. The role spans HEOR and evidence generation, pricing and contracting, payer engagement, and policy, working backwards from what payers need to be convinced of value, often with limited trial data. Beyond access expertise, the Head of Access Strategy must lead the function through the new era of AI‑augmented evidence and value work. Leadership Behavior Leads with AI‑augmented judgment Uses data and AI to decide faster and better while owning judgment calls AI cannot make Orchestrates across boundaries, delivering through influence, shared goals, and trust as functional silos dissolve not through positional control Drives change and adoption, pulling the team through AI and digital change, creating psychological safety to experiment, and naming resistance rather than tolerating it Obsesses over patient outcomes, anchoring decisions to the patient's find‑to‑adherence journey, treating advocacy and equity as strategic Models learning agility, reskilling continuously, experimenting, and failing fast in the open so the team does the same Builds talent density, running lean with an elite bar, making hard talent calls and developing those they keep Qualifications Bachelor’s degree required; advanced degree (MBA, PharmD, MPH, MS, PhD) strongly preferred 10+ years of market access and payer experience, gained within the pharmaceutical/biotech industry or from external environments such as payer organizations, managed care, consulting, or health economics firms 7+ years of leadership experience managing teams and cross‑functional initiatives Demonstrated expertise in payer access strategy: pricing, contracting, reimbursement, formulary management Proven track record in GTN management and financial modeling Strong financial acumen, including P&L impact and pricing strategy Experience with value proposition development and payer evidence generation Experience in rare disease or specialty therapeutics preferred Excellent communication, negotiation, and executive influence skills Ability to navigate complex, highly regulated environments while managing multiple priorities Why choose us? Bring the miracles of science to life alongside a supportive, future‑focused team Discover endless opportunities to grow your talent and drive your career, whether through promotion or lateral move, at home or internationally Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high‑quality healthcare, prevention and wellness programs and at least 14 weeks gender‑neutral parental leave Lead market access strategy for a high‑growth $2.2B rare disease business with a clear path to $3.1B Play a pivotal role in launching a landmark AATD therapy that will transform patient lives Join the US Leadership Team and shape payer strategy across the entire rare disease portfolio Drive formulary adoption and reimbursement for breakthrough therapies with cutting‑edge HEOR, RWE, and payer evidence strategies Be part of a mission‑driven team chasing the miracles of science to improve patients’ lives Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital, domestic partnership or civil union status, sex, gender, gender identity or expression, affectional or sexual orientation, disability, veteran or military status or liability for military status, domestic violence victim status, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here. #J-18808-Ljbffr BioSpace