Postdoctoral Research Associate - Heinzen Lab

Position Summary The Heinzen laboratory in the Division of Pharmacotherapy and Experimental Therapeutics, in collaboration with the Eshelman Institute for Innovation, at the University of North Carolina at Chapel Hill is looking to immediately fill multiple postdoctoral fellowship positions to study molecular mechanisms across multiple types of genetic epilepsies to identify convergent disease mechanisms and drug targets. The successful candidates will be part of a highly interdisciplinary environment to develop induced pluripotent stem cell‑derived neuronal models of genetic epilepsies and apply cutting‑edge technologies including electrophysiology, single‑cell RNAseq, chromatin conformation capture, optogenetics, genetically encoded biosensors of neurotransmission, and live‑cell imaging to study cellular and molecular signatures associated with genetic epilepsies. Well‑defined cellular and molecular signatures will be fed into the drug‑discovery pipeline and/or subjected to CRISPR screens to identify druggable genetic modifiers as part of the Drug Discovery Initiative led by the Eshelman Institute of Innovation. The ultimate goal is for postdoctoral fellows to develop specialized skill sets to drive independent research programs that can launch independent research careers. Minimum Education And Experience Requirements Ph.D. in a biological sciences discipline (e.g., neuroscience, molecular biology, pharmacology, cell biology, molecular genetics). Publication record demonstrating research productivity. Required Qualifications, Competencies, And Experience Excellent communication, organization, and writing skills. Willingness to be part of collaborative team science. Strong data analysis skills. Preferred Qualifications, Competencies, And Experience Experience with human induced pluripotent stem cell models preferred but not required. Special Instructions For information on UNC Postdoctoral Benefits and Services. #J-18808-Ljbffr Inside Higher Ed