Medical Director, Pediatric Phase 1 Clinical Trials Unit - Cancer Institute

Medical Director, Pediatric Phase 1 Clinical Trials Unit - Cancer InstituteOutstanding opportunity for Medical Director of Phase I Oncology Clinical Trials with prestigious Children's Health System in South Florida. Nicklaus Children's Health System and Nicklaus Children's Pediatric Specialists (NCPS), the health system's physician-led multispecialty group practice, have an outstanding opportunity for a visionary who is interested in actively shaping a growing program, expanding access to novel therapies, leading clinical trials, and contributing to translational research that will deliver the next generation of therapeutic breakthroughs for children and families in Florida and beyond.Qualifications:Board-certified, fellowship-trained pediatric hematologist-oncologist with a minimum of 5-7 years of experienceLeadership experience in early phase (Phase I) oncology clinical trials and service as Principal Investigator on oncology trialsBackground providing clinical care to children and adolescents with cancer in a tertiary or quaternary pediatric settingSavvy in IND processes, FDA regulatory pathways, and good clinical practice in clinical researchPrior program building or multi-site leadership in oncology clinical researchFamiliarity with cellular therapy, immunotherapy, or precision oncology platformsEstablished track record of extramural funding (federal, foundation, or industry)Responsibilities:Act as principal clinical and scientific leaderOversee the integrity, safety and growth of the early-phase portfolioServe as PI on investigator-initiated and industry-sponsored Phase I trialsLead protocol development, safety monitoring, toxicity management, and DSMB reportingEnsure robust integration of translational science, biomarkers, and precision oncology approaches into study design and executionManage IND submissions and FDA communicationMaintain rigorous pharmacovigilance, and ensure compliance with federal, state, institutional, and incubator-specific requirements, aligning local operations with statewide Cancer Connect goalsInitiative Overview:The Nicklaus Children's Hospital Pediatric Cancer Research Initiative, supported through the Florida Cancer Connect Collaborative Research Incubator, is a multiyear, state-funded effort to expand early-phase pediatric oncology trials, precision therapeutics, and statewide access to innovative cancer care for children and adolescents. The initiative is embedded within the Pediatric Early Phase (Phase I/first-in-child) Oncology Clinical Trials Program, positioning Nicklaus Children's as a leading site for high-risk and refractory malignancies and directly supporting the hospital's role within Florida's coordinated pediatric cancer strategy.Academic Affiliation:Our academic affiliation is with Florida International University (FIU). This position includes eligibility to apply for a faculty appointment at FIU Herbert Wertheim College of Medicine. Each year, Nicklaus Children's Hospital trains: 84 pediatric residents and 2 chief residents 49 subspecialty fellows in 17 distinct training programs.About Nicklaus Children's Health System:Where Your Child Matters Most™ For more than 75 years, Nicklaus Children's Health System has stood as a beacon of hope for children and families across the state of Florida and beyond. Nicklaus Children's Hospital is South Florida's #1 nonprofit, freestanding specialty licensed hospital exclusively for children. Nicklaus Children's provides pediatric care across a growing network of hospital and community-based partnerships, including within NCH North Hospital in Naples, Jupiter Medical Center, select Baptist Health Hospital pediatric emergency units, and Nicklaus Children's Hospital Fort Lauderdale and Nicklaus Children's Hospital Coral Springs, each located on the campuses of Broward Health. The hospitals and their network of more than 35 outpatient locations offer lifesaving care in Miami-Dade, Broward, Martin and Palm Beach counties. Outpatient locations include an array of urgent care, pediatric primary care and specialty care centers and are either hospital-based or outpatient locations under Nicklaus Children's Pediatric Specialists, LLC (NCPS). Providing a pipeline of future physicians and groundbreaking research, Nicklaus Children's is an academic and clinical affiliate of the Florida International University Herbert Wertheim College of Medicine and home to centers of excellence including the Helen & Jacob Shaham Cancer & Blood Disorders Institute, Orthopedic, Sports Medicine and Spine Institute, Neuroscience Institute and Heart Institute. The 474-bed system is renowned for excellence in all aspects of pediatric medicine, with many programs routinely ranked among the nation's best by U.S. News & World Report since 2008. Nicklaus Children's also includes a nonprofit physician practice subsidiary with more than 40 pediatric specialties and an ambulatory surgery center.Discover South Florida:The communities in South Florida offer all the advantages of a tropical, diverse and metropolitan region. Enjoy abundant sunshine and warm weather year-round with easy access to numerous recreational opportunities, beaches, cultural and professional sporting venues, and international travel.