VP, Chief Enterprise Architect

As the VP, Chief Enterprise Architect, you will set the vision for enterprise-wide architecture—driving digital and AI-enabled transformation, and influencing business strategy at the highest levels. You’ll bring consultative leadership, deep technical expertise, and executive presence to orchestrate change and deliver lasting impact across our global business.In this role, you will set the target-state architecture across digital, data, AI, cloud, and core platforms. You will ensure our technology landscape accelerates R&D innovation, modernizes manufacturing, enhances commercial effectiveness, and strengthens regulatory resilience.This is a strategic executive leadership role requiring consultative influence, technical depth, and the ability to translate emerging technologies into scalable, secure, and AI-ready enterprise capabilities across a highly regulated global organization.Key ResponsibilitiesVision & Enterprise StrategyDefine and lead a multi-year enterprise architecture strategy aligned to business growth, AI scale, operational excellence, and regulatory requirements.Establish a clear target-state architecture and phased transformation roadmap across global business units.Ensure technology investments reduce complexity, enable reuse, and accelerate innovation velocity.Enterprise AI & Platform EnablementDesign the enterprise AI and data platform architecture to enable AI-at-scale across R&D, manufacturing, and commercial functions.Establish standards for responsible AI, model governance, data interoperability, and secure AI deployment in regulated environments.Accelerate AI solution deployment through reusable patterns, reference architectures, and scalable digital platforms.Executive Influence & Business PartnershipAdvise senior business and technology leaders, translating complex enterprise challenges into actionable architecture roadmaps tied to measurable outcomes.Align architecture priorities to business KPIs such as time-to-market, productivity gains, cost optimization, and risk reduction.Serve as enterprise design authority for major transformation programs and strategic investments.Governance & RiskDesign pragmatic, agile architecture governance that balances innovation with security, compliance, and enterprise risk management.Lead enterprise standards across cloud, data, integration, security, and AI domains.Guide architecture strategy during M&A, integration, and organizational redesign efforts.Organizational Leadership & EvangelismBuild, inspire, and scale a high-performing global architecture community across enterprise, domain, data, AI, and platform disciplines.Champion architecture as a strategic capability — shifting from review-and-approve to enable-and-accelerate.Foster a culture of learning, experimentation, and disciplined execution.Stakeholder EngagementCultivate strong partnerships across global business functions, external innovators, and strategic technology partners.Represent enterprise architecture in executive forums and strategic planning discussions.Why You?We are seeking professionals with the following skills and qualifications to help us achieve our goals:Advanced degree (MS, MBA, or equivalent) and relevant certifications (TOGAF, advanced cloud or AI architecture credentials) would be preferred.Significant enterprise architecture leadership experience, including service as Chief Architect or Enterprise Architecture VP within a complex, global organizations.Experience in global, highly regulated environments such as bio-pharma, healthcare, or life sciences would be ideal.Demonstrated ownership of enterprise-wide digital and AI transformation strategies delivering measurable business impact.Experience architecting scalable AI, cloud, data, and platform ecosystems in regulated industries.Proven ability to influence executive stakeholders and simplify complex technical strategies into business-aligned action.Strong execution discipline — balancing strategic vision with practical delivery.Demonstrated success reducing enterprise complexity, rationalizing legacy estates, and accelerating platform adoption.Thought leadership through industry forums, publishing, or standards bodies.Experience integrating architecture strategies post-M&A and during large-scale operating model transformation.Proven ability to mentor senior architects and build federated global architecture communities.SkillsAutomation Technology, Cloud Based Services, Computer Programming, Configuration Management (CM), Container Orchestration, Database Management, Enterprise Backups, Infrastructure Security, Network Services, Operating Systems (OS), Scripting, Service Integration, System Monitors, TroubleshootingWhy GSK?Uniting science, technology and talent to get ahead of disease together.GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at View email address on click.appcast.io where you can also request a call.Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. Click the link where you will find answers to multiple questions we receiveImportant notice to Employment businesses/ AgenciesGSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at SummaryLocation: UK – London – New Oxford Street; USA - Pennsylvania - Philadelphia; India - Karnataka - Bengaluru; USA - North Carolina - DurhamType: Full time