Manager, Drug Product, Commercial Manufacturing

Revolution Medicines seeks a Manager for Drug Product Commercial Manufacturing to oversee technical transfers, qualification activities, and commercial manufacturing operations for assigned products and CMO sites. The role focuses on solid oral dose manufacturing including spray-dried dispersions, granulation, coating, and related unit operations, with cross-functional partnership across Quality, Supply Chain, and Regulatory.

Responsibilities

• Provide primary technical oversight for assigned CMO sites and commercial drug-product operations
• Assess CMO site capability, capacity, facility infrastructure, and readiness for commercial demand
• Manage manufacturing technical transfers, process implementation, and post-transfer monitoring
• Direct equipment qualification, validation, PPQ, and continued process verification activities
• Manage manufacturing deviations, investigations, CAPAs, and post-approval changes

Requirements

• Bachelor's or Master's degree in Pharmaceutical Sciences, Chemical Engineering, or related technical discipline
• Approximately 6–8 years of pharmaceutical manufacturing or related experience
• Expertise in solid oral dose drug-product manufacturing processes and unit operations
• Experience with CMO technical oversight, site assessment, and manufacturing transfers
• Knowledge of equipment qualification, validation, and continued process verification
• Familiarity with cGMP compliance, deviation management, and regulatory documentation