Raven StealthCo- Director/Senior Director, Biology

Position Overview The Senior Director/Director Biology will report directly to the Head of Research/CSO and work closely with cross‑functional leaders to translate the delivery platform into therapeutic programs with deep biological insights. They will formulate and implement the scientific strategy for development of our disease biology platform from in‑vitro assays to in‑vivo pre‑clinical pharmacology, recruit, mentor and coach the scientific team, and shape the overall scientific vision and therapeutic programs. Responsibilities Build a research team of three while strategically leveraging consultants and CROs to accelerate early‑stage discovery. Lead a deep understanding of initial indication area biology by developing relationships with KOLs and extending further insights into the MOA of lead target(s) utilizing physiological and next‑generation "omic" measurement tools. Synthesize large datasets alongside mechanistic insights in cell biology and physiology to identify and prioritize novel targets actionable via the company’s platform. Develop and own the suite of in‑vitro and in‑vivo assays needed for lead indication biology, including endpoint measurements for target manipulation across relevant cell types. Lead and manage CRO partnerships supporting in‑vivo pharmacology, including design and evaluation of readouts across relevant disease models. Collaborate with the VP of Delivery to analyze the biodistribution and pharmacodynamic metrics of the delivery platform, including assessments of proximal oligonucleotide effects on target genes (e.g., IHC, spatial transcriptomics, and mass spectrometry). Contribute to company‑level strategic decisions on target and program selection, with particular attention to how biology findings inform platform development. Communicate strategy and progress to internal and external stakeholders, supporting fundraising efforts and strategic partnering as the company matures. Track developments in lead indication biology and the competitive landscape. The Individual The Senior Director/Director is a hands‑on builder—someone equally comfortable at the bench, managing a small team, and interpreting complex datasets to make program decisions. The ideal candidate brings demonstrated success delivering preclinical therapeutic programs, with deep mastery of at least one relevant area of biology, significant in‑vivo pharmacology experience, and a track record of translating novel ideas into rigorous, reproducible results. Prior experience in our specific indication is a plus but not a requirement. This person will also represent the company credibly to the Board, investors, and the broader biotechnology community, and must be an effective mentor and manager. At a personal level, we are looking for someone who is intellectually curious, collaborative, humble, and driven. The candidate will have the adaptability to thrive in an early‑stage environment where priorities shift and roles are broad. They must bring sound judgment, strong organizational instincts, and the ability to move fluidly between hands‑on experimental work and strategic thinking. We are building a culture where science and the team come first; this person should embody that ethos and bring the interpersonal range to lead effectively within it. Qualifications From an educational perspective, we are seeking an individual with a Ph.D. and/or M.D. in a relevant discipline such as chemistry or protein engineering. Education is an important index of achievement, orientation, and intellectual capacity, but will not constitute the primary variable in this decision process. Personal characteristics, leadership abilities, technical fluency, creativity, work ethic, behavioral flexibility, and demonstrated accomplishments will serve as key components in the evaluation of candidates. Salary Base salary range: $210,000 – $280,000 USD per year. The role may also be eligible for annual bonus and long‑term incentives. Compensation and benefits may be updated in the future. #J-18808-Ljbffr Raven (RA Ventures)