Medical Science Liaison (South Central)

Join Immatics and shape the future of cancer immunotherapy ; one patient at a time!

Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME , a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Why Join Us?

• Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
• Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
• Global Impact: Contribute to therapies that make a lasting impact on patients globally.

We are seeking a Medical Science Liaison to support our Medical Affairs team. The Medical Science Liaison will be responsible for high-quality scientific exchange, clinical research support, and insight generation throughout pre-launch to launch initiatives within their assigned territory engaging with thought leaders, investigators, medical centers and their staff.

FLSA Classification : Salary, Exempt

Schedule : 8:00 AM – 5:00 PM; Monday to Friday; Remote

Reports to : Executive Director, Medical Affairs

What You’ll Do:

We are seeking a Medical Science Liaison to play a critical role in advancing Medical Affairs objectives through high-quality scientific exchange, clinical research support, and insight generation. This role acts as a key scientific partner to thought leaders, investigators, and medical centers and staff, supporting peer-to-peer scientific exchange of information around emerging data and evolving science.

This position will support pre-launch through launch activities for a TCR T-cell therapy in melanoma, while also contributing to pipeline development across additional solid tumor indications as programs progress. You will engage closely with clinical sites and medical centers to support development programs, contribute to evidence-generation efforts, and provide meaningful field insights that inform internal decision-making. This role requires strong scientific acumen, experience working with complex clinical data, and the ability to operate independently while partnering effectively across a collaborative Medical Affairs organization.

Essential Functions:

Scientific Exchange & External Engagement

• Conduct high-quality, data-driven scientific exchange with though leaders, investigators, medical centers and staff, and healthcare payors
• Identify, develop, and maintain relationships with regional and national thought leaders to support scientific exchange, collaboration, and insight generation
• Establish and sustain trusted scientific partnerships that support long-term engagement across development and launch phases
• Act as a credible scientific resource for discussions related to emerging data, evolving standards of care, and unmet medical needs

Evidence Generation & Scientific Support

• Provide scientific and medical input to support ongoing clinical development programs
• Support clinical trial site identification and ongoing site engagement by contributing scientific expertise and field-based perspectives in partnership with internal teams
• Contribute to evidence-generation activities across the product lifecycle, including pre-launch through launch activities
• Engage external experts to identify evidence gaps and inform future research priorities
• Support development programs in melanoma and additional solid tumor indications as pipeline assets advance

Insights & Strategic Contribution

• Identify and communicate high-quality medical insights from the field to inform internal clinical and evidence strategies
• Identify trends and evolving data needs that may influence development plans or future research directions
• Deliver insights in a clear, timely, and actionable manner to internal stakeholders

Cross-Functional Collaboration

• Collaborate closely with Clinical Development, Clinical Operations, Regulatory, Commercial, Market Access, and other internal stakeholders
• Contribute scientific expertise to cross-functional initiatives while maintaining appropriate Medical Affairs independence
• Support alignment across teams to ensure coordinated, scientifically rigorous medical activities

Medical Activities & Compliance

• Execute medical initiatives such as advisory boards, investigator meetings, scientific congresses, and educational programs
• Maintain a current understanding of the therapeutic landscape, evolving standards of care, and competitive environment
• Ensure all activities are conducted in accordance with company policies, industry regulations, and ethical standards

Pre-Launch & Launch Readiness

• Engage thought leaders, investigators, medical centers and staff during the pre-launch phase to understand treatment approaches, unmet needs, and patient flow, and to support medical education and scientific data dissemination
• Participate in cross-functional launch activities by providing scientific input and field perspective to support Medical Affairs execution
• Support scientific readiness for launch through peer-to-peer discussions on emerging clinical data, mechanism of action, and site readiness for future patient access and operational integration
• Executive launch-phase medical activities, including scientific exchange at congresses, advisory boards, and investigator meetings
• Gather and communicate early post-launch medical insights to inform ongoing evidence generation and Medical Affairs activities

Required Experience and Education:

• Bachelor's degree in life sciences or related field is required
• Minimum of 5+ years of experience as a Medical Science Liaison within the biopharmaceutical or biotechnology industry
• Demonstrated experience supporting clinical development programs and scientific exchange activities
• Proven ability to interpret and communicate complex clinical and scientific data
• Excellent written, verbal, and presentation skills
• Ability to work independently while collaborating effectively in a matrixed environment
• Willingness to travel within assigned territory and to national scientific congresses to support Medical Affairs activities

Preferred Experience and Education:

• Advanced scientific degree is preferred (MD, PharmD, PhD, APN, or equivalent)
• Experience in oncology, cellular therapy, or other complex specialty therapeutic areas
• Experience supporting late-stage development and launch readiness activities
• Exposure to investigator-initiated research, publications, and real-world evidence initiatives
• Scientific credibility and sound judgement
• Strong execution and organizational skills
• Effective cross-functional collaboration
• Clear, professional communication
• High standards for integrity, compliance, and scientific rigor

This is a sedentary position (at least 50% of time) in a typical office environment. There may be frequent interruptions with moderate noise levels and frequent use of printers, copiers, scanners, computers and other office equipment. Ability to sit, talk, walk, hear and communicate verbally and in writing is required. Occasional lifting of objects up to 25 lbs is expected.

Travel required:

Ability and willingness to travel ~60% of the time in assigned territory and key congresses.

• Communicating Verbally – expressing or exchanging ideas by means of the spoken word to impart oral information to others to convey detailed spoken instructions or other workers accurately, loudly or quickly.
• Hearing – the ability to hear, understand, and distinguish speech and/or other sounds one-on-one, group or conference, telephone, and other sounds.
• Keyboarding – entering data or text into a computer or other machine by means of a keyboard. Devices include a traditional keyboard, 10 key-pad, touch screens and others.
• please see additional physical demands at

Work authorization/security clearance requirements

Legal eligibility to work in the United States is required. Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment

Affirmative Action/EEO statement

Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.

What do we offer?

At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of Paid Time off, granted up front each year and prorated for first and last year of employment.
• Sick Time Off – 56 hours
• 12 Paid Holidays
• 100% Employer-Paid Life Insurance up to at 1x annual salary
• 100% Employer Paid Short- and Long-Term Disability Coverage
• 401(k) with Immediate Eligibility & company match…
• You are eligible for 401(k) plan participation as of your first paycheck.
• The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
• Partially paid Parental Leave for eligible employees. (3 weeks)
• Additional voluntary employee paid coverages including Accident, Hospital Indemnity, and Critical Illness Employee Paid Identity Theft Protection and Pet Insurance.

Professional Growth

• Opportunities to work with leading experts in the field of T-cell immunotherapy
• Company provided learning and development opportunities
• Fast paced, high demand collaborative and dynamic environment