Director / Senior Director, Strategic Analytics & Reporting

Commercial Analytics Lead

We are seeking a highly skilled and motivated Commercial Analytics Lead with a strong background in data modeling and analytics, visualization, reporting, and predictive modeling. The ideal candidate will have experience in leveraging a variety of data analytics tools and programming languages to build custom data tables and analyze large datasets to draw insights and support decision-making processes across sales, marketing, market access and other cross-functional partners. Ideally this candidate should have relevant experience in pharmaceutical/biotech space in analytical capacity.

• Lead the development and implementation of sales force strategies, including targeting, sales force sizing and alignment, and incentive compensation planning, to drive sales growth and business performance.
• Analyze multiple data sources, KPIs, trends, and market events to provide strategic insights on business performance.
• Process, analyze, and visualize patient claims data, providing reliable reporting on key metrics.
• Ensure accurate and timely delivery of weekly, monthly, and quarterly reporting of brand's performance to senior management and the broader commercial organization.
• Support commercial initiatives and product performance assessment with relevant analytics and insights.
• Clearly communicate health of the business and insights, present and provide strategic guidance to leadership.
• Support pre-launch planning and launch execution through partnership with cross functional stakeholders, develop KPIs and tracking tools.
• Design and implement field operation needs, such as CRM, power BI reporting, and targeting lists, to ensure data quality and accuracy.
• Support the development of the company's Data Warehouse and reporting capabilities
• Develop and implement weekly, monthly, and quarterly dashboards for various internal stakeholders, utilizing data-driven insights to inform strategic decision-making.
• Use predictive modeling to enhance and optimize business outcomes.
• Foster a culture of continuous learning and professional development, while mentoring team members to support individual and team success.
• Maintain the highest standards in commercial data, reporting, and analytics, while proactively sharing insights to uncover new growth opportunities.
• Collaborate closely with various functional stakeholders, such as Sales, Marketing, Patient Support and Services, Access and Reimbursement, IT, and Finance to ensure cross-functional alignment and execution of commercial strategies.
• Manage relationships with data vendors, ensuring the quality of final products and maintaining high standards of data integrity.

Candidate Profile & Requirements:

• Bachelor's degree in Statistics, Engineering, Computer Science, Mathematics, Economics, Data Science, or related quantitative field required; advanced degree preferred.
• Director: Minimum 8–10 years of relevant experience in commercial analytics, business analytics, or data science.
• Senior Director: Minimum 10–12+ years of relevant experience with increasing leadership responsibility.
• Experience supporting biopharmaceutical commercial organizations, including sales, marketing, market access, or patient services analytics.
• Demonstrated experience translating complex data into actionable insights to support commercial strategy, performance reporting, and launch readiness.
• Proficiency with SQL and analytics programming languages (Python or R) and experience with data visualization tools such as Power BI, Tableau, or similar platforms.
• Strong analytical, communication, and cross-functional collaboration skills.

At Karyopharm, base pay is one part of a competitive total rewards package that includes comprehensive benefits (medical, dental, vision, 401(k), and more), equity and the potential to receive annual target bonuses. Actual pay is based on factors such as location, experience, skills, education, and internal equity. We maintain broad salary ranges to reflect market conditions and the specialized nature of our work. The anticipated base salary range for this position is $210 K - $270 K USD.

Our Value Proposition:

This is a uniquely exciting time to join Karyopharm Therapeutics where we are pioneering the science of nuclear export inhibition to develop differentiated therapies for patients with cancer. We are building upon an established commercial foundation in multiple myeloma while advancing the potential of selinexor across additional hematologic and solid tumor cancers including myelofibrosis and TP53 wild-type endometrial cancer, areas where patients continue to face significant unmet needs.

Our lead therapy, XPOVIO® (selinexor), is a first-in-class inhibitor of exportin 1 (XPO1) and is approved in the U.S. for adults with relapsed or refractory multiple myeloma, with approvals in more than 50 countries and territories outside the U.S. We are also exploring opportunities to evaluate XPO1 inhibition across myeloproliferative neoplasms and TP53 wild-type driven solid tumors using next-generation compounds, including eltanexor.

As we prepare for our next phase of growth, we are continuing to invest in critical capabilities across the organization to support future opportunities and deepen our impact in oncology. We are looking for talented people who are motivated by meaningful work, energized by growth and momentum, and excited by the opportunity to help shape what comes next in a collaborative, fast-moving environment where individual contributions are visible and valued.

Learn more at Karyopharm Therapeutics.