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Postdoctoral Associate

Stony Brook

Job Description - Postdoctoral Associate (2603366) Postdoctoral Associate Required Qualification: (as evidenced by an attached resume) Doctoral Degree (or foreign equivalent) in RNA biology, molecular biology, cell biology, genetics, biochemistry, biomedical sciences or closely related field in hand by the start of the appointment. Preferred Qualification: Research experience in one or more of the following areas is preferred: RNA biology and post-transcriptional gene regulation; kidney biology or polycystic kidney disease; mouse genetics, transgenic mouse models, and animal phenotyping; mammalian cell culture, primary cells, or kidney organoids; or RNA-targeting technologies such as siRNA and antisense oligonucleotides. Experience with eCLIP, iCLIP, CLIP-seq, or related RNA-protein interaction assays is highly desirable but not required. Job Description: The Postdoctoral Associate will conduct NIH-funded research in the Aboudehen Laboratory within the Division of Nephrology and Hypertension, Department of Medicine. The laboratory studies RNA biology in autosomal dominant polycystic kidney disease (ADPKD) through two major research programs: (1) determining how disease-associated long noncoding RNAs regulate cyst initiation and progression, and (2) defining how RNA-binding proteins, RNA-RNA interactions, and other post-transcriptional mechanisms regulate PKD1 mRNA and polycystin-1 dosage. The lab uses complementary approaches in RNA biology, molecular and cellular biology, mouse genetics, and kidney-disease modeling to investigate ADPKD mechanisms and identify potential therapeutic targets. Research may involve genetically engineered mouse models of PKD, human kidney epithelial and primary ADPKD cells, and RNA-targeting technologies. The incumbent will conduct experiments, analyze and interpret data, prepare manuscripts and presentations, and ensure that all research is performed according to Stony Brook University policies and procedures. Specific Duties Design and conduct molecular, cellular, and animal experiments investigating lncRNA function, PKD1 mRNA regulation, polycystin-1 biology, and ADPKD pathogenesis. Studies may include genetically engineered mouse models, kidney phenotyping, mammalian cell culture, and primary ADPKD cells. Collect, analyze, interpret, and document experimental data; perform literature searches; and apply specialized approaches in RNA biology, molecular biology, mouse genetics, and kidney-disease research. Prepare manuscripts, scientific presentations, research reports, and grant-related materials. Maintain mouse-colony and experimental records, laboratory materials, and equipment, and assist with ordering research supplies as needed. Perform other duties as assigned, including attending scientific conferences, seminars, and meetings. Special Notes The Research Foundation of SUNY is a private educational corporation. Employment is subject to the Research Foundation policies and procedures, sponsor guidelines and the availability of funding. FLSA Exempt position, not eligible for the overtime provisions of the FLSA. Minimum salary threshold must be met to maintain FLSA exemption. Stony Brook University is committed to excellence in diversity and the creation of an inclusive learning, and working environment. All qualified applicants will receive consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, familial status, sexual orientation, gender identity or expression, age, disability, genetic information, veteran status and all other protected classes under federal or state laws. If you need a disability-related accommodation, please call the university Office of Equity and Access (OEA) at View phone number on click.appcast.io or visit OEA . In accordance with the Title II Crime Awareness and Security Act a copy of our crime statistics can be viewed here. Visit our WHY WORK HERE page to learn about the total rewards we offer. The starting salary range (or hiring range) to be offered for this position is noted below, it represents SBU’s good faith and reasonable estimate of the range of possible compensation at the time of posting. Job Number 2603366 Official Job Title Postdoctoral Associate Job Field Post Doctoral Schedule Full-time Shift Day Shift Shift Hours : 8:30am - 5:00pm #J-18808-Ljbffr Stony Brook

Vacancy posted 4 days ago
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