Clinical/Development - Senior Associate Scientist

Job Description

Job Description

Title: Clinical/Development - Senior Associate Scientist
Location: Cambridge, MA
Duration: 6 Months

Position Summary
We are seeking a motivated Senior Associate Scientist to join the Advanced In Vitro Models team. This role will contribute to the development and application of human cell based disease models and engineered in vitro systems to support therapeutic discovery.
The ideal candidate will have hands-on experience with human iPSC culture and differentiation, as well as RNA- and protein-based analytical techniques. The successful candidate will be detail-oriented, scientifically curious, and comfortable working in a collaborative, fast-paced research environment.
Key Responsibilities

• Maintain, expand, and differentiate human iPSCs into relevant cell types to support disease modeling and therapeutic discovery.
• Perform molecular and cellular characterization using techniques such as qPCR, RNA and protein analysis, imaging, sequencing, and functional assays.
• Support the development, optimization, and characterization of advanced in vitro systems, including co-culture and 3D models.
• Design and execute experiments, analyze data, troubleshoot technical challenges, and communicate conclusions clearly.
• Maintain accurate experimental records and ensure high standards of data quality and reproducibility.
• Present findings internally and collaborate effectively with cross-functional discovery teams.

Preferred Qualifications

• Experience designing and executing CRISPR/Cas9 genome-editing workflows and validating engineered cell lines.
• Experience with advanced imaging techniques, organoid culture, or other complex human cell based systems.

Basic Qualifications

• BS with 4 6 years or MS with 2 4 years of relevant industry or academic experience, including hands-on experience with human iPSC culture and differentiation.
• Strong mammalian cell culture and molecular biology skills, with experience using RNA- and protein-based readouts.
• Strong organizational and communication skills, attention to detail, and the ability to work both independently and collaboratively.