Senior Director - Enterprise Applications

Summary

This position is an executive technology leader accountable for Pharming’s enterprise application strategy, governance, performance, and value realization across the company. The role ensures that Pharming’s core business applications enable scalable growth, operational excellence, regulatory compliance, data-driven decision-making, and business transformation. Acting as a strategic partner to the Executive leader of Digital Transformation & IT, Executive Committee, and senior business leaders, the person in this role translates business priorities into enterprise-wide application capabilities and ensures that technology investments deliver measurable business value. This role is responsible for shaping the future application landscape, simplifying complexity, strengthening operational resilience, and ensuring that critical platforms are secure, compliant, integrated, and fit for purpose in a global biopharmaceutical environment. This is an important moment of transformation for Pharming’s digital and technology capabilities, as they evolve from a traditional support function into a more integrated, enterprise-wide enabler of business value. You will have the opportunity to influence how applications, data, technology, processes, and ways of working develop across the organization, helping to build scalable, resilient, and future-ready capabilities that support Pharming’s continued growth. This position is based in our Warren, NJ office with a hybrid schedule of 2-3 in office days per week. Responsibilities Enterprise applications strategy and governance Define and execute the enterprise applications strategy, roadmap, and governance model. Ensure the application portfolio supports Pharming’s strategic priorities, operating model, and growth ambitions. Drive simplification, standardization, modernization, and rationalization of the application landscape. Establish clear ownership, lifecycle management, investment prioritization, and decision-making across the portfolio. Business partnership, delivery and transformation Partner with executive and senior business leaders to translate strategic priorities into application capabilities. Ensure applications enable effective business processes, user productivity, compliance, and data-driven decision-making. Govern business demand and ensure technology investments are prioritized based on value, risk, urgency, and strategic alignment. Oversee major application programs, enhancements, upgrades, integrations, and transformation initiatives. Ensure delivery of projects within agreed scope, quality, timeline, budget, compliance, and business outcome expectations Ensure application initiatives are aligned with enterprise architecture, security, data, and infrastructure strategies Compliance, risk, security, and resilience Ensure enterprise applications operate in accordance with applicable regulatory, quality, privacy, cybersecurity, validation, audit, and data integrity requirements. Maintain strong governance over application controls, access management, change control, documentation, and audit readiness. Identify and mitigate application-related risks, including technical debt, vendor dependency, lifecycle risk, service continuity, and compliance exposure. Ensure critical applications have appropriate support, continuity, recovery, and resilience arrangements Vendor, partner, and commercial management Own strategic relationships with software vendors, implementation partners, managed service providers, and consultants. Ensure partners deliver against agreed service levels, contracts, business outcomes, quality standards, and compliance expectations. Drive commercial discipline across licensing, renewals, vendor performance, contracts, and external delivery models. Service excellence and continuous improvement Ensure reliable, user-focused application support and service performance. Govern incident, problem, change, release, and enhancement management across the application portfolio. Use service metrics, business feedback, and risk indicators to drive continuous improvement. Improve application usability, stability, integration quality, data flow, and operational efficiency. Leadership and capability development Lead, develop, and mature the enterprise applications function. Build a team culture focused on accountability, business partnership, delivery excellence, and continuous improvement. Develop internal capability while effectively leveraging external partners. Qualifications Bachelor’s or Master’s degree in Information Technology, Computer Science, Business Administration, Engineering, Life Sciences, or a related field. At least 15 years of applicable experience including significant senior leadership experience in enterprise applications, preferably in a global or regulated organization Experience in biotechnology, healthcare, or life sciences a plus. Proven experience owning application strategy, portfolio governance, lifecycle management, and enterprise roadmap delivery. Strong experience with major enterprise platforms such as ERP, CRM, HR. Demonstrated ability to influence executive stakeholders and translate business strategy into technology-enabled outcomes. Familiarity with GxP, computer system validation, and regulatory inspection readiness. Experience with application modernization, SaaS/cloud platforms, integration strategy, data enablement, and portfolio rationalization. Methodologies such as ITIL, PMP, PRINCE2, Agile/Scrum, or relevant platform/cloud certifications. Strong understanding of compliance, validation, cybersecurity, privacy, audit, data integrity, and risk management in regulated environments. Proven vendor, partner, contract, budget, and service performance management experience. Experience leading teams, managing change, and building scalable operating models. Fluent English required; Dutch or other European languages are an advantage. Willingness to travel internationally, estimated at 10-20%. Commitment and alignment to Pharming’s mission, core values, and behaviors. Executive presence and strategic judgement. Strong business partnering and stakeholder influence. Commercial and financial acumen. Ability to balance growth, compliance, resilience, and innovation. Clear communication and decision-making. Change leadership and organizational maturity building. Strong ownership, accountability, and delivery discipline. Who we are We’re built on a simple belief: people living with rare diseases deserve more. Pharming is a global biotechnology company taking on some of the toughest rare disease challenges. We develop and commercialize innovative therapies for rare and ultra-rare immunological and genetic diseases with significant unmet need, where our scientific and commercial expertise, long-term commitment, and real partnership can help advance care. We put patients at the heart of our work. Their insights, along with those of caregivers, clinicians, scientists, and parters, shape our strategy, guide our decisions, and help turn science into meaningful progress. We keep it simple, act with urgency, and get it done – expanding access to approved therapies, advancing high-value pipeline programs, and building a leading global rare disease company. Our vision is simple: a world where people living with rare diseases don’t wait for progress or care. Together with the communities who inspire us, we’re opening new possibilities – proving that breakthroughs aren’t just discovered. They’re created together. Ready to make a difference? Join us. What it’s like to work here At Pharming, every role helps move rare disease therapies closer to the people who need them. We make it happen together, across teams, disciplines, and borders, because breakthroughs don’t happen in silos. Rare diseases are complex, and meaningful progress takes people who ask better questions, challenge each other, and turn insight into action. Here, you won’t work on the sidelines. Pharming is a place for builders, problem-solvers, and bold thinkers who move with urgency, take ownership, and stay focused on what matters most: improving the lives of people living with rare diseases. Advancing rare disease care isn’t the work of one team or one leader. It’s all of us, building what’s next together. Salary range Pharming takes into consideration a combination of candidate’s work experience, training, and education, as well as the scope of the role, complexity, and external market and internal value when determining a salary level. The base salary range for this job is from $240,000 to $300,000 per year. Compensation & benefits Flexible hybrid work schedule to promote a healthy work-life balance Competitive compensation package including annual target bonus Long-term incentive program 401(k) plan with company match Paid Time Off (PTO) 13 Company Holidays per year Excellent benefit plans including medical, dental, and vision Flexible spending accounts Company-provided life insurance, short-term disability, and long-term disability plans Optional accident, hospital indemnity, critical illness, and pet insurance plans Tuition reimbursement program Health and wellness program Choice of company provided mobile phone or cell phone stipend Additional information Pharming Healthcare, Inc. is a merit-based equal opportunity employer. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected classes. An applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request via email to View email address on click.appcast.io. Unsolicited resumes from agencies should not be forwarded to Pharming. Pharming will not be responsible for any fees arising from the use of resumes through this source. Pharming will only pay a fee to agencies if a formal agreement between Pharming and the agency has been established. The Human Resources/Talent Acquisition department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement.