Senior Technical Project Manager (Durham)
Optomi, LLC
Optomi, in partnership with a leading medical organization, is seeking a Senior Technical Project/Program Manager to lead complex digital technology projects and enterprise initiatives from planning through delivery, release, and post-implementation transition. This role will be responsible for coordinating cross-functional teams, managing project schedules, risks, dependencies, budgets, governance, and stakeholder communication while ensuring predictable and successful delivery. The Senior Technical Project/Program Manager will serve as the primary point of contact for assigned projects and initiatives, partnering closely with Agile teams, engineering, product, business stakeholders, vendors, and enterprise technology teams. The ideal candidate has strong technical project management experience and can translate complex technical information into clear, actionable updates for business partners and executive leadership.
What You’ll Enjoy
- Leading complex digital technology projects and initiatives from planning through implementation and transition to production support.
- Working across Agile teams, engineering, product, architecture, business, vendors, and enterprise technology organizations.
- Managing project plans, roadmaps, milestones, release timelines, risks, dependencies, budgets, resources, and delivery constraints.
- Supporting Agile delivery through PI planning, sprint and release coordination, dependency management, governance, and cross-team execution.
- Serving as a key liaison between technical teams, business stakeholders, vendors, and leadership to maintain alignment and visibility.
What You Bring
- Bachelor’s degree or advanced degree preferred.
- 5+ years of experience in technical project management, program management, or a related field. In lieu of a degree, 7+ years of related experience.
- Significant experience leading complex technology projects, technical programs, or enterprise initiatives through planning, execution, implementation, and transition.
- Strong experience managing project risks, issues, assumptions, dependencies, decisions, resources, budgets, forecasts, and stakeholder expectations.
- Strong understanding of Agile methodologies, SDLC, technical dependencies, release planning, governance, and enterprise delivery practices.
- Experience coordinating cross-functional teams across technology, product, business, architecture, finance, vendors, and executive leadership.
- Ability to communicate complex technical information clearly through executive updates, project status reporting, risk escalations, and stakeholder communications.
- Experience with vendor management, business readiness, change management, release coordination, and production transition.
- PMP, Agile, Scrum, SAFe, or related project management certification is a plus.
- ...McAdams seeks a senior Water Resources leader to drive stormwater projects in the Raleigh/Durham area. You will lead a production team, mentor staff, manage client relationships, and guide proposals... ...viability. The role emphasizes technical site civil engineering for...Senior
- ...Toshiba Global Commerce Solutions is seeking a Technical Project Manager III to lead governance, reporting, and delivery coordination across Professional Services. You will consolidate milestones, risks, and actions for executive visibility and own RAID and action management...Senior
- ...digital transformation projects alongside people... ...four core businesses: Management Consulting, SAP Business... ...life sciences sector, Senior SailPoint IdentityIQ (... ...troubleshooting, and technical governance across its... ...Information Location: Durham, NC Hybrid position...SeniorHourly payContract workRemote workFlexible hours2 days per week3 days per week
- ...Wayne J. Griffin Electric, Inc. is seeking an experienced Senior Project Manager to oversee multiple electrical construction projects valued at $5M+ out of our Durham, NC office. You will lead project teams, coordinate with general contractors, suppliers and field staff...SeniorFor contractorsWork at office
- ...firm is looking for a Sr. Healthcare Business Analyst located in Durham, NC. This contract-to-hire role requires 6+ years of experience... ...excellent communication skills to navigate complex environments and manage high-level stakeholder interactions. Responsibilities include...SeniorContract workLocal area
$184k - $264.5k
...Site Reliability Operations Technical Lead to serve as the senior technical individual... ...reliability and support at our Durham, North Carolina site.... ...will also lead site-level projects, represent local... ...site asset and inventory management across lifecycle, refresh...SeniorPermanent employmentWork at officeLocal areaRelocation$97k - $182k
...lead to the same place. We are currently searching for a Senior IT Project Manager. The Senior IT Project Manager is responsible for carrying... ...Manager has excellent documentation experience and superior technical knowledge and is both internally team-focused and...SeniorTemporary workLocal areaRemote workRelocationFlexible hours- ...Housekeeping Supervisor for Summit Hospitality Group/Hyatt Place Durham Southpoint is responsible for ensuring property guestrooms/... ...Establishes and maintains open and collaborative relationships with all management and staff· Recognizes Associates and uses an "open door policy"...SeniorFlexible hoursShift work
- Fidelity Investments Senior Data Base Engineer Contract- One Year, will more than likely extend if based on performance Location: Must be local to either Raleigh/Durham or Dallas/Fort Worth The Team As a Senior Database Engineer , you will be applying your software development...SeniorContract workLocal area
- ...Senior Project ManagerClient is seeking an experienced Senior Project Manager. This management role will work with multiple internal and external stakeholders, project teams, divisions, departments, and vendors to strategize, implement, and maintain the Child Welfare Information...SeniorContract workWork experience placementLocal area
- ...Analog Devices, Inc. in Durham, NC seeks a Principal Engineer, Segment Marketing – Power Solutions to define strategy for Healthcare and... ..., and convert customer needs into qualified opportunities. This senior role requires independent execution and influential senior-level...Senior
$30 - $37 per hour
...Immediate need for a talented Senior Registered Nurse Case Manager. This is a 06+months contract opportunity with long-term potential and is located in Durham, NC(Onsite). Please review the job description below and contact me ASAP if you are interested. Job...SeniorContract workLocal areaImmediate start$65 - $71 per hour
...Position Title: Senior Utility Engineer Work Location: Durham, NC 27713 Assignment Duration... ...: Own and manage site utility, electrical... ...maintenance plans, drawings, and technical specifications... ...controllers Solid project management capabilities...SeniorWork experience placementLocal area$245.6k
...revenue acceleration. We are seeking a Senior Director of Outbound Sales Development... ..., and growing SaaS company! Location: Durham, NC This role requires a strong onsite... ...Successful ~ Bachelor's degree in business management ora relatedfield, or equivalent...SeniorWork at officeRelocation- ...Senior Data EngineerPosition: Senior Data Engineer/ Durham, NC, 6 Months Contract RemoteDynamic work schedule - This is... ...Technology group supporting our Wealth Management Domain within Fidelity's... ...providing the Data Engineering technical expertise and leadership used by...SeniorContract workWork at officeWork from home
$55 - $60 per hour
...summary: We are looking for a Program/Project Manager with experience managing large... ...delivery outcomes. Maintain sufficient technical and product knowledge to anticipate delivery... ...preferred. location: Durham, North Carolina job type: Contract...Hourly payContract workTemporary workWork experience placement- ...stakeholders?2. What are the most critical things a project manager should communicate to senior leadership?Project: State Health PlanTop 3-4 Required... ...benefits administration experienceDescription:• Serve as technical coordination point for projects and initiatives of...Senior
- ...Senior Manager/Manager, Marketing AlphaDetect — Durham, NC AlphaDetect is a non-profit organization powered by the Alpha-1 Foundation, solely dedicated to... ...This role blends hands-on content development, project management, cross-functional collaboration, and strong...SeniorFull timePart timeWork at office
- ...experience in software development, with at least 2 years leading complex IT projects/initiatives (Mid – Senior level). Strong technical exposure and experience in web application development.Project Management Implementation - Hands on experience running technology initiatives,...Contract work
- ...Hospital Senior Account Manager Territory includes but is not limited to Raleigh and Durham The Hospital Senior Account Manager supports and advances formulary access, protocol and order set readiness, discharge pathway support, and demand generation across targeted...SeniorLocal areaNight shift
- ...Position Summary The Senior Manager, E-Commerce & Digital Product serves as ECMD's business owner for e-commerce and customer-facing... ...adoption. It combines e-commerce leadership, business analysis, technical fluency, quality assurance, analytics, communication, and...SeniorFor contractors
- ...Principal Investigator Durham, NC IMA Clinical Research | New Site Launch IMA Clinical Research is expanding into Durham, NC and seeking a Principal Investigator for our newest clinical research site. This is an opportunity to support a new site launch while working...Full timePart timeLocal areaFlexible hours
- ...Blue Cross and Blue Shield of North Carolina is looking for a Senior Technical Program Manager to initiate and lead strategic, enterprise-scale technical projects and programs in Durham. This role coordinates cross-functional teams, manages portfolio-level delivery, and...Senior
- ...We are developing our in-house AI/ML systems and models at our Durham NC HQ and are building a team to lead these efforts. As such, we... ...AI models for scientific applications to serve as a Vitakey’s technical lead for AI modeling. You will be responsible for developing new...Senior
- Sr Technical Project/Program ManagerJob#: 3047017Job Description:St Technical... .../Program ManagerLocation: Durham, North Carolina (Partial... ...schedules. This position involves managing allocated resources from... ...related field is required. For a senior role, 5-8 years of project/...SeniorRemote work
- ...Location: Westlake, TX and Durham, NC Job Description We... .... The candidate will provide technical leadership across multiple development... ...to client stakeholders and senior leadership, translating... ...driving technical excellence, managing architectural risks and...SeniorFull time
- ...you approach your first 90 days as the Technical Program Manager for the Technology & Operating Model... ...teams without direct authority, aligned senior stakeholders, and restored structure... ...Serve as technical coordination point for projects and initiatives of enterprise-level...Remote work
- ...Senior Project Scheduler is a leader and contributor in the organization within the scheduling function on multiple utility-scale solar and... ...project sites as needed ( Physical Requirements/Work Environment Durham, NC headquarters with some travel to sites and for training (...SeniorWork experience placement
$70 - $79.38 per hour
...Job Title: Biopharma Project Manager Location: Durham, NC Employment Type: W2 Contract – 12 Months with Possibility for Extensions... ...forums. Facilitate communication and alignment among technical, operational, project, and business stakeholders....Weekly payContract work- ...Posted 05/19/2026 - Lane - Blythe Const - JV Expense (3435) - Project Management - Bachelor's Degree Lane Construction is one of America’s... ...will support large highway construction projects in the Raleigh-Durham, NC area. Influences the financial performance of a project by...Contract workFor subcontractor
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Technical Project Manager (Durham). Be the first to apply!
- web project manager Durham, NC
- technical project manager Durham, NC
- remote technical project manager Durham, NC
- digital project manager Durham, NC
- IT project manager Durham, NC
- senior living Durham, NC
- senior manufacturing engineer Durham, NC
- senior application support engineer Durham, NC
- senior devops Durham, NC
- senior internal audit Durham, NC




