Engineer I
AgileOne
We are seeking an Engineer I to support laboratory and bioprocessing activities focused on downstream purification of large, complex molecules. This role is ideal for someone with a strong scientific foundation who is comfortable working in a laboratory environment and has an understanding of bioprocess purification, scaling principles, and wet chemistry techniques. The successful candidate will contribute to laboratory-scale process characterization, troubleshooting, data interpretation, and technical documentation while collaborating closely with cross-functional teams.
Responsibilities:- Support laboratory activities related to downstream bioprocess purification of large, complex molecules.
- Perform wet chemistry laboratory techniques including pipetting, buffer preparation, filtration, dilution, and stoichiometric calculations.
- Apply scientific understanding of purification operations and bioprocess scaling principles to laboratory activities and process development.
- Conduct laboratory-scale process characterization studies and support experimental activities.
- Operate and work with analytical laboratory instrumentation such as plate readers, densitometers, thermocyclers, cIEF, UV/Vis spectrophotometers, and HPLC/UPLC systems.
- Troubleshoot experimental and equipment-related technical issues and assist in identifying effective solutions.
- Support method development and method transfer activities as needed.
- Maintain accurate laboratory records, including laboratory notebooks, chemical inventories, and data management documentation.
- Interpret, analyze, and present scientific and technical data to support project objectives and decision-making.
- Collaborate effectively with team members and cross-functional partners while maintaining a strong focus on laboratory safety, quality, and scientific rigor.
- Bachelor's degree in Science, Engineering, or a related scientific/technical field is strongly preferred.
- Comfortable working in a laboratory environment.
- Understanding of downstream bioprocess purification processes.
- Scientific understanding of purification operations involving large, complex molecules.
- Technical understanding of bioprocess scaling principles.
- Demonstrated wet chemistry laboratory skills, including pipetting, buffer preparation, filtration, dilution, and stoichiometry.
- Strong technical writing skills and experience maintaining laboratory records and scientific documentation.
- Strong technical problem-solving, data interpretation, and presentation skills.
- Excellent collaboration and team-working abilities.
- Experience working with adjuvant and/or LNP processing.
- Experience with tangential flow filtration (TFF), including microfiltration and ultrafiltration.
- Experience with analytical instrumentation, including plate readers, densitometers, thermocyclers, cIEF, UV/Vis spectrophotometers, and HPLC/UPLC systems.
- Experience supporting laboratory operations.
- Experience working in an industry environment.
- Experience conducting laboratory-scale process characterization studies.
- Experience troubleshooting experimental and equipment-related technical issues.
- Experience with method development and method transfer.
- Experience working in GMP and/or GLP environments.
- This position requires hands-on laboratory work and the ability to work effectively in a collaborative, technical environment.
- Candidates should demonstrate strong scientific curiosity, attention to detail, and the ability to communicate technical information clearly.
Vacancy posted 3 days ago
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