Scientist II, Mammalian Cell Culture - 368

Job Description

Job Description

Job Title:  Scientist II 

Pay Rate: Up to $62/hr. W2
Job ID: 368

Location : Alameda California 94502 

Duration: 6 Months  

Shift: 8am-5pm 

Possibility to extend or convert: This is to cover for a resource who is on temporary leave. There is possibility for extension. The team likely will have a FTE role open early next year that they would consider this person for. 

Interview Process: 1 round: 1 hour long virtual panel interview 
Notes - candidate ideally will be comfortable explaining cell culture and cell viability assays. Industry experience is preferred. Academia will be considered.

Nice to have: CellTiter-Glo.

This is a BSL2 lab, the molecules they will be working with are considered hazardous because they are new chemicals, they are not high risk. Some of the reagents they work with are considered caustic but they have standard protections.

Education:

• BS/BA degree in related discipline and a minimum of four years of related experience; or,
• MS/MA degree in related discipline and a minimum of two years of related experience; or,
• Equivalent combination of education and experience.

Experience:

·         Extensive hands-on experience with basic molecular and biochemical techniques (RNA, PCR, western blot, ELISA, fluorescent imaging) and cell biology techniques (mammalian cell culture, phenotypic assays) are highly desirable.

·         Proficient in use of GraphPad Prism and MS Excel, Word, PowerPoint.

·         Drug discovery experiences are highly desirable. 

Knowledge/Skills:

·         General knowledge of cellular, biochemical, and molecular techniques, theories, and practices.

·         General understanding of how the individual experiments fit within a larger research program to meet organizational goals.

·         General understanding and application of scientific principles, theories, and concepts in field of specialty and other related disciplines.

·         Complete understanding of the goals of the experiments and how they fit into the overall program.

·         Applies extensive scientific and technical expertise in area of specialty.

·         Ability to effectively capture data and results.

·         Strong communication skills, excellent work ethics, self-motivated and work effectively both in a team environment and independently.

·      Computer proficiency including MS Word, MS PowerPoint and MS Excel required. 

1. Education  
2. • BS/BA in Biology, Cell Biology, Molecular Biology, Biochemistry, or related scientific discipline plus 4+ years of relevant industry experience , OR 
   • MS degree in a related scientific discipline plus 2+ years of relevant industry experience  
   • PhD candidates will not be considered  
3. Mammalian Cell Culture - Extensive hands-on experience maintaining and working with mammalian cell lines in a biotech or pharmaceutical drug discovery environment. 
4. Cellular / Viability Assays -  Direct experience performing cell viability assays, routine screening assays, and evaluating compound activity. 
5. ELISA and/or AlphaLISA Assays - Experience performing, troubleshooting, and analyzing plate-based assays. 
6. Drug Discovery Experience - Prior experience supporting small-molecule drug discovery programs is required. 
7. Data Analysis & Reporting - Ability to analyze experimental results, generate dose-response curves, and communicate findings effectively. 

Strong Plus: 

• Western blot experience 
• Experience with high-throughput or routine screening workflows 
• GraphPad Prism proficiency 

SUMMARY/JOB PURPOSE:

The successful candidate will be highly motivated, comfortable in a dynamic and energetic team-based environment, and passionate about discovering new cancer therapeutics. This role involves development of cell-based functional assays, and evaluation of small molecule inhibitors in those assays to support oncology drug discovery projects. This job requires reliable execution of experiments, interpretation and analysis of data, and problem solving. The ideal candidate will have good lab practices and be able to multi-task. The candidate must have good organizational skills, communication, and teamwork skills as well as flexibility and versatility to meet tight deadlines in a dynamic, fast-moving environment.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

·         Works independently to plan, design, and perform research experiments to support oncology drug discovery programs.

·         Analyzes and interprets scientific data under general supervision.

·         Maintains and operates scientific apparatus to perform research experiments.

·         May develop new methodologies and laboratory protocols in conducting general research duties within assigned area of responsibility.

·         Prepares and organizes data for presentation. Presents data and reports on project status at individual, group, and departmental research meetings.

·         Maintains familiarity with current scientific literature relevant to the research experiments or program.

·         Maintains laboratory notebook in a complete, consistent, and concise manner in accordance with company intellectual property policies and practices.

• Adheres to good health and safety practices and compliance with applicable EH&S safety rules and participates in mandatory safety training programs.

·         Other responsibilities as assigned

WORKING CONDITIONS:

·         Environment: primarily working in laboratories or in office

·         Exposures encountered, such as hazardous materials, extreme cold.

·         Travel not required