Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Principal Decision Scientist

$197.3k - $313.7k

Salesforce.Com Inc

To get the best candidate experience, please consider applying for a maximum of 3 roles within 12 months to ensure you are not duplicating efforts.

Job Category

Data

Job Details

About Salesforce

Salesforce is the #1 AI CRM, where humans with agents drive customer success together. Here, ambition meets action. Tech meets trust. And innovation isn't a buzzword - it's a way of life. The world of work as we know it is changing and we're looking for Trailblazers who are passionate about bettering business and the world through AI, driving innovation, and keeping Salesforce's core values at the heart of it all.

Ready to level-up your career at the company leading workforce transformation in the agentic era? You're in the right place! Agentforce is the future of AI, and you are the future of Salesforce.

Position Overview:

As a Decision Scientist within the Data & Analytics organization, you will collaborate with cross-functional teams to measure agentic impact, influence leaders with in-depth analysis, and strategically partner with Product Managers to shape the future of our work. You will work in a dynamic organization that sits at the intersection of analytics, AI, and automation, and is building the framework for the agentic enterprise in real time.

Core Responsibilities
  • Agentic Evaluation Frameworks: Develop and scale methodologies to evaluate the performance, reasoning, and reliability of agentic workflows and AI systems.

  • Causal Inference & Attribution: Build sophisticated models to solve complex attribution problems. You will distinguish between incremental gains and organic trends using various data science and modeling techniques at your disposal.

  • Experimental Design: Lead the design and analysis of complex experiments, moving beyond simple A/B testing into multivariate testing, switchback experiments, and quasi-experimental designs for cases where randomization is impossible.

  • Statistical Leadership: Refine and author methodologies, frameworks, analytical packages, and mentor junior team members.

  • Strategic Influence: Translate complex statistical findings into clear, actionable narratives for executive leadership, influencing the long-term product and business roadmap.

Technical Requirements
  • Background: Master's or PhD in a highly quantitative field such as Statistics, Mathematics, Economics, Computer Science, Operations Research, or similar field.

  • Experience: 10+ years of experience in a quantitative role, with a proven track record of deploying causal models or experimental frameworks in a production environment.

  • Programming: Adept proficiency in Python or R (specifically the PyData stack: Pandas, NumPy, SciPy, Statsmodels, Scikit-learn).

  • Data Retrieval: Mastery of SQL for complex data extraction, feature engineering, and performance tuning within cloud data warehouses (e.g., Snowflake, BigQuery).

  • Modeling Mastery: Deep experience in high-dimensional regression, time-series analysis, and forecasting techniques.

  • Agentic Systems: Familiarity with LLM evaluation metrics (LLM-as-a-judge) and the unique statistical challenges posed by non-deterministic AI outputs.

Join our innovative team and contribute to our data-driven success. Apply today to help us build and maintain the data infrastructure that drives our business forward.

Unleash Your Potential

When you join Salesforce, you'll be limitless in all areas of your life. Our benefits and resources support you to find balance and be your best , and our AI agents accelerate your impact so you can do your best . Together, we'll bring the power of Agentforce to organizations of all sizes and deliver amazing experiences that customers love. Apply today to not only shape the future - but to redefine what's possible - for yourself, for AI, and the world.

Accommodations

If you need a reasonable accommodation during the application or the recruiting process, please submit a request via this Accommodations Request Form.

Please note that Salesforce uses artificial intelligence (AI) tools to help our recruiters assess and evaluate candidates' resumes and qualifications throughout the recruiting process. Humans will always make any candidate selection and hiring decisions. Please see our Candidate Privacy Statement for more information about how we use your personal data and your rights, including with regard to use of AI tools and opt out options.

Posting Statement

Salesforce is an equal opportunity employer and maintains a policy of non-discrimination with all employees and applicants for employment. What does that mean exactly? It means that at Salesforce, we believe in equality for all. And we believe we can lead the path to equality in part by creating a workplace that's inclusive, and free from discrimination. Know your rights: workplace discrimination is illegal. Any employee or potential employee will be assessed on the basis of merit, competence and qualifications - without regard to race, religion, color, national origin, sex, sexual orientation, gender expression or identity, transgender status, age, disability, veteran or marital status, political viewpoint, or other classifications protected by law. This policy applies to current and prospective employees, no matter where they are in their Salesforce employment journey. It also applies to recruiting, hiring, job assignment, compensation, promotion, benefits, training, assessment of job performance, discipline, termination, and everything in between. Recruiting, hiring, and promotion decisions at Salesforce are fair and based on merit. The same goes for compensation, benefits, promotions, transfers, reduction in workforce, recall, training, and education.

In the United States, compensation offered will be determined by factors such as location, job level, job-related knowledge, skills, and experience. Certain roles may be eligible for incentive compensation, equity, and benefits. Salesforce offers a variety of benefits to help you live well including: time off programs, medical, dental, vision, mental health support, paid parental leave, life and disability insurance, 401(k), and an employee stock purchasing program. More details about company benefits can be found at the following link: to the San Francisco Fair Chance Ordinance and the Los Angeles Fair Chance Initiative for Hiring, Salesforce will consider for employment qualified applicants with arrest and conviction records. At Salesforce, we believe in equitable compensation practices that reflect the dynamic nature of labor markets across various regions. The typical base salary range for this position is $197,300 - $313,700 annually. In select cities within the San Francisco and New York City metropolitan area, the base salary range for this role is $237,700 - $344,700 annually. The range represents base salary only, and does not include company bonus, incentive for sales roles, equity or benefits, as applicable.
Vacancy posted 9 days ago
Similar jobs that could be interesting for youBased on the Principal Decision Scientist in San Francisco, CA vacancy
  •  ...therapeutic biologic products.  We are a world-class team of scientists and leaders united by a shared mission to advance industry-leading...  ...across functions and influence scientific and technical decisions. Strong organizational skills and the ability to manage multiple... 
    Principal
    Full time
    Local area

    AbbVie

    San Francisco, CA
    7 days ago
  • $202.5k - $236.25k

     ...positive impact.We are seeking a highly motivated and skilled Principal Scientist, Translational Genetics to join our growing team. The...  ...the patient front and center in all we do - all actions and decisions are in service of the patient and their caregivers. We champion... 
    Principal

    Cytokinetics

    San Francisco, CA
    4 days ago
  • $202.5k - $236.25k

    Principal Scientist, Computational Chemistry page is loaded## Principal Scientist, Computational Chemistrylocations: South San Francisco, Californiatime...  ...enhance compound design capabilities and enable data-driven decision-making*.* Emphasis will be placed on utilization of... 
    Principal

    Cytokinetics

    San Francisco, CA
    3 days ago
  • $150.7k - $279.9k

    F. Hoffmann-La Roche AG is looking for a Principal Scientist to contribute to innovative research in statistical genetics and AI/ML. This role...  .... You will develop methodologies that improve the decision-making process in therapeutic development. Compensation includes... 
    Principal

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    1 day ago
  • Yoh, A Day & Zimmermann is seeking a Principal Research Scientist in Cancer Biology to join a pioneering research program in South San Francisco. This role demands expertise in cancer biology to drive drug discovery projects and analyze complex biological data. The ideal... 
    Principal

    Yoh,-A-Day-

    San Francisco, CA
    1 day ago
  •  ...are seeking an innovative and highly motivated Supervising Principal Scientist with expertise in cell therapy process development and people...  ...recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more... 
    Principal
    Flexible hours

    Cellares

    South San Francisco, CA
    9 days ago
  • Biogen, Inc. is seeking a Principal Scientist in Biomarker Data Sciences to lead multi-omics analyses of clinical trial datasets at the West Coast Hub. In this pivotal role, you will generate biological insights that inform clinical development strategies, particularly... 
    Principal

    Biogen, Inc.

    San Francisco, CA
    3 days ago
  • $268k - $384k

     ...Senior / Principal ML Scientist, Foundation Models for Life Sciences San Francisco, CA USA Your Impact at LILA Lila is building a platform where AI and automation co-evolve to solve the hardest problems in medicine. Within Life Science AI (LSAI), the Foundation... 
    Principal
    Full time
    Work at office
    Local area
    Flexible hours

    Lila Sciences

    San Francisco, CA
    11 days ago
  • Principal Scientist, Late Stage Upstream Process Development (San Francisco, CA) Client is seeking an experienced and driven scientist/engineer to lead late-stage upstream cell culture process development activities for clinical and commercial-stage large molecule programs... 
    Principal
    Contract work

    Cedent

    San Francisco, CA
    4 days ago
  • $159k - $207k

     ...translational medicine. Denali is founded on the collaboration of leading scientists, industry experts, and investors who share the vision that...  ...filtration studies to inform and support large‑scale process decisions. Maintain existing workflows to provide purification support... 
    Principal
    Contract work
    Work experience placement
    Local area

    Denali Therapeutics Inc

    South San Francisco, CA
    1 day ago
  • $167.4k - $310.8k

     ...Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more...  ...techniques. We are seeking a Senior or Principal Machine Learning Scientist to join the Foundation...  ...long‑horizon reasoning and complex decision‑making. Domain Translation: Translate... 
    Principal
    Local area
    Worldwide
    Relocation package

    NLP PEOPLE

    South San Francisco, CA
    5 days ago
  • $143.2k - $265.9k

    The Position The Opportunity We are seeking a creative and highly motivated Principal Scientist, Medicinal Chemist to join our R&D team. This is a primarily lab-based, technical leadership position within the Peptide Therapeutics department. In this lab-based leadership... 
    Principal
    Local area
    Relocation package

    Genentech

    San Francisco, CA
    4 days ago
  •  ...Translational Pharmacology to lead and drive preclinical pharmacology efforts across our pipeline. This individual will play a central, decision-making role in translating innovative science into rigorous, in vivo proof-of-concept and clinically actionable pharmacology... 
    Principal

    5AM Ventures

    Emeryville, CA
    28 days ago
  • $150.7k - $279.9k

     ...patient stratification strategies. Opportunity We are seeking a Principal Scientist (Bioinformatics track) to lead cutting‑edge statistical...  ...and who wants to see their work influence real therapeutic decisions. Responsibilities Lead end‑to‑end human genetics analyses across... 
    Principal
    Local area
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    1 day ago
  • $141k - $188k

    About This Role As a Principal Scientist in Biomarker Data Sciences within the Clinical Biomarkers group at the West Coast Hub, you will lead the charge in multi‑omics analyses of extensive clinical trial datasets, with a particular focus on NGS and proteomics. This role... 
    Principal
    Temporary work
    Local area

    Biogen, Inc.

    San Francisco, CA
    3 days ago
  • $120.8k - $224.3k

     ...what makes us Genentech! The Opportunity The Cell and Individualized Therapies Department has an exciting opportunity for a Principal Scientist with a strong background in cell therapy drug product process development. The selected candidate will work as a part of the... 
    Principal
    Local area
    Relocation package

    Genentech

    San Francisco, CA
    1 day ago
  • $140k - $250k

    Principal Scientist, Protein Sciences, Analytical Characterizations September 2025 Department: Technology Position Summary: TCG Labs-Soleil is seeking a highly experienced and driven Principal Scientist to lead our analytical efforts and join our multidisciplinary Protein... 
    Principal
    Full time
    Temporary work
    Flexible hours

    Valid8 Financial, Inc.

    San Francisco, CA
    5 days ago
  • $141k - $188k

    About This Role:As a Principal Scientist in Biomarker Data Sciences within the Clinical Biomarkers group at the West Coast Hub, you will lead the charge in multi-omics analyses of extensive clinical trial datasets, with a particular focus on NGS and proteomics. This role... 
    Principal
    Temporary work
    Local area

    Biogen

    San Francisco, CA
    4 days ago
  •  ...transform the lives of patients while transforming your career. Principal Scientist-PKDM, Modeling and Simulation What you will do Let’s do this...  ...implement quantitative analysis and strategies to inform decision making in drug development by using mathematical modeling... 
    Principal
    Flexible hours

    Amgen SA

    South San Francisco, CA
    2 days ago
  • Principal Scientist Computational Biology & Translational AI (Oncology Precision Medicine) Join Amgen's Mission of Serving Patients. At Amgen...  ...evaluation, interpretability, and scientific reliability in decision‑critical environments. Working knowledge of clinical... 
    Principal
    Remote work
    Flexible hours

    Initial Therapeutics, Inc.

    South San Francisco, CA
    3 days ago
  • $124.3k - $230.9k

    Overview We are seeking a highly motivated Senior Scientist or Principal Scientist with a strong record of laboratory innovation and technical...  ...high‑quality data to guide molecular and formulation decisions and inform program decisions across discovery and early development... 
    Principal
    Local area
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    1 day ago
  • $124.3k - $230.9k

    Senior Scientist / Principal Scientist - Synthetic Molecule Analytical Chemistry We are seeking an experienced scientist with a strong record...  ...cGMP, ICH, and regulatory expectations. Informing program decisions across discovery and early development by generating high‑quality... 
    Principal
    Local area
    Relocation package

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    1 day ago
  • $159.6k - $251.2k

     ...Francisco are seeking a highly motivated and accomplished Associate Principal Scientist to join our Quantitative Biosciences (Pharmacology)...  ...complex results into actionable insights that inform project decisions. CRO and external partner management: work effectively with... 
    Principal
    For contractors
    Shift work

    MSD Malaysia

    South San Francisco, CA
    4 days ago
  • $196k - $242k

     .... Position Summary We are seeking an accomplished Senior Principal Research Scientist in Computational Chemistry with significant pharmaceutical...  ...computational work that influences medicinal chemistry decisions and project outcomes Ability to manage priorities across... 
    Principal
    Temporary work
    Local area
    Remote work
    1 day per week

    IDEAYA Biosciences, Inc.

    South San Francisco, CA
    1 day ago
  • $71.25k - $187k

     ...We give our best effort to our work, and we put people first. Position Overview We are seeking a highly motivated and dedicated scientist with knowledge and experience of cellular and molecular biology who shares our passion to help patients live with higher quality of... 
    Principal
    Full time
    H1b
    Worldwide
    Flexible hours

    Eli Lilly and Company

    San Francisco, CA
    1 day ago
  •  ...transform the lives of patients while transforming your career. Principal Scientist - PKDM (Large Molecule Project Team Representative) What you...  ...forecast project needs Driving hypothesis-based scientific decision-making and contributing to program strategy across discovery... 
    Principal
    Flexible hours

    Amgen SA

    South San Francisco, CA
    5 days ago
  • $196k - $242k

     ...Position Summary We are seeking an accomplished Senior Principal Research Scientist in Computational Chemistry with significant pharmaceutical...  ...deliver computational work that influences medicinal chemistry decisions and project outcomes Ability to manage priorities across... 
    Principal
    Temporary work
    Work at office
    Local area
    Work from home

    Initial Therapeutics, Inc.

    South San Francisco, CA
    2 days ago
  • Gravity Engineering Services Pvt Ltd. is seeking a Principal/Distinguished AI/ML Researcher in San Francisco, California. This role involves...  ...capabilities, focusing on reasoning, planning, and adaptive decision-making systems. The ideal candidate will possess over 15 years... 
    Principal

    Gravity Engineering Services Pvt Ltd.

    San Francisco, CA
    2 days ago
  • $124.3k - $265.9k

    F. Hoffmann-La Roche AG is seeking a Senior Scientist / Principal Scientist specializing in synthetic molecule analytical chemistry in South San Francisco, California. The role involves troubleshooting analytical methods and contributing to regulatory submissions. Ideal... 
    Principal

    F. Hoffmann-La Roche AG

    South San Francisco, CA
    5 days ago
  • $196k - $242k

    IDEAYA Biosciences, Inc. is looking for a Senior Principal Research Scientist in Computational Chemistry in South San Francisco, CA. This role involves leading drug design efforts and mentoring while applying computational methods to influence project outcomes. Working... 
    Principal
    Remote job
    1 day per week

    IDEAYA Biosciences, Inc.

    South San Francisco, CA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Principal Decision Scientist. Be the first to apply!