Senior Machine Learning Scientist, Climate & Hydrology
$127k - $205.9k3M HEALTHCARE
Company Description Flagship Pioneering is a bioplatform innovation company that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health, sustainability and beyond exponentially accelerate scientific progress in areas ranging from disease detection and treatment and nature-positive agriculture to novel applications of AI that are driving the creation of new technologies. What sets Flagship apart is our ability to advance science and technology by uniting innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. The Role We are seeking a Senior Machine Learning Scientist, Climate and Hydrology to lead the scientific direction and machine learning development for hydrology-aware climate modeling within our broader environmental modeling platform. This role sits at the intersection of hydrology, weather and climate science, and large-scale machine learning. The Sr. Scientist will help shape how hydrologic process understanding, climate data, and modern ML methods are brought together in next-generation prediction systems, with emphasis on scientifically grounded model development and evaluation. The individual in this role will work across science, ML, engineering, and data teams to define research priorities, guide model training and benchmarking, build reproducible workflows, and translate scientific insight into scalable model development. This is a cross-functional role requiring strong technical depth, structured scientific thinking, and the ability to move between foundational research and applied execution. Key Responsibilities Lead scientific and technical efforts at the intersection of hydrology, climate science, and machine learning. Help define research priorities, modeling directions, and evaluation strategies for next-generation climate and environmental prediction systems. Contribute to the development and improvement of ML-based modeling approaches informed by physical and Earth system science. Work with large-scale climate, weather, hydrology, and remote sensing datasets to support model development and scientific analysis. Build and oversee reproducible workflows for data processing, model training, benchmarking, and validation. Collaborate closely with research, engineering, and data teams to translate scientific goals into scalable technical execution. Guide assessment of model performance, uncertainty, and scientific robustness across a range of environmental conditions and applications. Communicate findings through internal reviews, external collaborations, publications, and technical presentations. Help shape the broader scientific roadmap and contribute to team growth and cross-functional leadership. Professional Experience & Qualifications PhD in machine learning, computational science, Earth science, atmospheric science, hydrology, AI, computer science, or a related quantitative discipline. 5+ years of postdoctoral, industry, or applied research experience in climate ML, weather ML, hydrologic modeling, Earth system modeling, or a closely related field. Demonstrated experience with ML-accelerated weather, climate, or hydrology models, with a strong publication track record in the area. Experience working with large climate datasets, including reanalysis products, remote sensing datasets, observational datasets, and model output. Experience with the computational infrastructure required to manage, preprocess, and train on large-scale climate datasets, preferably in the AWS ecosystem. Strong programming skills in Python and experience with modern ML frameworks such as PyTorch. Background in scientific ML, spatiotemporal modeling, data assimilation, hybrid physics-ML methods, or related approaches is strongly preferred. Ability to design rigorous evaluation frameworks, performance metrics, and benchmarking approaches for environmental prediction systems. Strong technical writing and communication skills, including reports, presentations, and peer-reviewed publications. Demonstrated ability to work independently in fast-paced, ambiguous environments while collaborating effectively across disciplines. Experience leading cross-functional scientific efforts, mentoring researchers, or helping define research roadmaps is preferred. Location Cambridge, MA or Boulder, CO (some travel to Cambridge, MA based headquarters if working from Colorado). About Flagship Pioneering Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact. Equal Opportunity Employer We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Salary and Benefits The salary ranges for this role are $127,000 - $205,900 (Colorado) and $168,000 - $231,000 (Massachusetts). Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Protocos currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Protoco's good faith estimate as of the date of publication and may be modified in the future. #J-18808-Ljbffr 3M HEALTHCARE
- ...physicians, providing critical information about the right treatments for the right patients, at the right time.The Senior Scientist, Applied Machine Learning and Generative AI, Pharma R&D will perform complex computational analyses and develop algorithms, causal models,...SeniorFull timeShift work
$119.7k - $222.3k
...Models the use of Artificial intelligence (AI) / Machine Learning (ML) approaches to enable model guided... ...in AI strategy, to be considered for Principal Scientist II. 4+ years of experience to be considered for Senior Principal Scientist. ~ Extensive and in-depth...Senior- ...contractor to join its Computational Precision Genetics team. This role is ideal for a data scientist with deep expertise in human genetic and genomic data analysis, strong machine learning capabilities, and hands-on experience integrating multi-omics datasets. The position...SeniorTemporary workFor contractorsRemote work
$136k - $264k
(Senior) Scientist, Multimodal Biological Reasoning Cambridge, MA USA Pioneering Intelligence builds on Flagship Pioneering’s legacy... ...computational ventures, harnessing recent advances in AI, machine learning, and data to accelerate fundamental research and create a...Senior- Senior Scientist - Immunology and Inflammation Senior Scientist - Immunology and Inflammation Get AI-powered advice on this job and more... ...discovery, synthetic biology, artificial intelligence, machine learning, and computer vision to develop exceptional products and deliver...SeniorFull timeContract workPart timeH1bWork at officeVisa sponsorshipShift work
$159.75k - $255.6k
...hard for a mission that matters at a company where you matter. Your Impact We are seeking highly skilled and innovative Machine Learning Scientists to join our AI team, focusing on AI applications (LLM and Computer Vision) in Cloud, Devices and Robotics. As a key...SeniorFull timeWork experience placementWork at officeRemote work- Research Leader / Senior Scientist (Medicinal Drug Design), Cambridge, MA Cambridge, MA Isomorphic Labs is applying frontier AI to help... .... A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting...SeniorContract workWork at office3 days per week
$150k - $180k
...to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto and Cambridge, MA is...SeniorLocal areaFlexible hoursWeekend work$144.8k - $227.9k
...Job Description Our Artificial Intelligence and Machine Learning (AI/ML) capabilities are critical accelerators of our mission... ..., and elucidating complex disease mechanisms. As Senior Machine Learning Scientist, you will be responsible for developing and training large...SeniorFull timeFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- ...manufacturing industry with its cutting-edge AI-enabled machine vision solutions. These solutions drive greater resilience... ...striving to make a difference every day, we are seeking a Senior Machine Learning Scientist to help build and maintain our cutting-edge machine...Senior
$138.6k - $257.4k
...Imaging Scientist The Oncology Pathology and Biomarkers group within Oncology Translational Research at Novartis Biomedical Research... ...multiplexed/high-plex tissue imaging platforms, including machine learning and computational methods for tissue image analysis...Senior- ...by TIME as a "Best Invention", MIT Technology Review as a "Top Climate Tech Company To Watch", and Fast Company as "One of the Next Big... ...- you've come to the right place. Form Energy is hiring a scientist to develop our next-generation gas diffusion electrodes for our...SeniorFull timeWork experience placementRelocation package
$139k - $165k
...passionate and motivated engineers and scientists with advanced degrees in engineering, computer... ...and C2 Division focuses on applying machine learning, statistics, estimation theory, and... ...resource management. The Role: As a Senior Research Scientist at STR, you will...SeniorFull timeWork at officeLocal areaNight shift$148.5k - $214.5k
Job title: Senior Principal Scientist Type 2 ImmunologyLocation:Cambridge, MAAbout the JobImmunology and Inflammation Therapeutic AreaWe have an exciting opportunity to join Sanofi's Translational Biology team as a Senior Principal Scientist within the Type 2 Immunology...SeniorFull time$72k - $215.6k
...portfolio of genetic medicines from early development through commercialization.Position Overview:We are seeking a highly motivated scientist with experience in chemistry, manufacturing and control (CMC) of genetic medicines to drive innovation efforts in the process...SeniorFull timeH1bVisa sponsorshipWork visaFlexible hours- Scholar Rock, Inc. seeks an accomplished leader in clinical bioanalysis to join the Bioanalytical Sciences team as Principal Scientist, Bioanalytical Specialist. You will provide scientific and operational leadership across our clinical programs, representing the bioanalytical...Senior
- Mass Digital Health is looking for a skilled toxicologist to join our Preclinical Safety group in Cambridge, MA. You will oversee the nonclinical safety program, engage with project teams, and formulate strategies for drug candidates ensuring safety and compliance. ...Senior
$100.76k - $174.2k
Job Description SummaryJob Title: Senior Scientist SummaryNovartis will not sponsor visas for this position.Novartis is unable to offer... ...Analysis, Detail-Oriented, Ethics, Gene Therapy, Immunology, Machine Learning (ML), Mammalian Cell Culture, Medical Research, Molecular...SeniorFull timeContract workWork experience placementWork from homeVisa sponsorshipRelocation package$169.8k - $355.4k
...you will have an opportunity to work with teams of applied scientists and engineers to deliver high quality computer vision models... ...dissertation, thesis or final project centered in Computer Vision and Machine Learning) with 8+ years relevant experience is preferred but not a...SeniorTemporary workFlexible hours- ...patients, at the right time.We are seeking an experienced Senior Scientist to join the Computational Biology, Pharma R&D team. This group... ...in Computational Biology, Bioinformatics, Biostatistics, Machine Learning, or a related field (or Masters degree with 4+ years of relevant...SeniorFull time
$115k - $161.67k
..., and is a key partner in PedDep, an initiative accelerating target discovery for childhood cancers.We are seeking an experienced scientist to lead the day-to-day operation of our internal CRISPR screening and profiling platform. This is a production-focused role: you will...SeniorFull timeLocal areaFlexible hours$115k - $215k
...timesLove to harness data; can design and conduct rigorous experiments to optimize materialsCan work autonomously and take initiative to learn new skills to complete an objectiveUnderstand the value of good documentationB.S., M.S., or PhD in a relevant science or engineering...SeniorFull timeWork at officeWorldwideFlexible hours$141k - $171k
...develop rigorous hypotheses.Collaborating closely with experimental scientists to ensure that data is effectively utilized for high-level... ...impact.Presenting scientific findings to broad audiences, including senior leadership, to drive decision making in program teams.Becoming...SeniorLocal area2 days per week3 days per week$115k - $215k
...the boundaries of what can be done with 3D printing.If you are a scientist or engineer with experience in polymer development who’s... ...optimize materialsCan work autonomously and take initiative to learn new skills to complete an objectiveUnderstand the value of good...SeniorFull timeWork at officeWorldwideFlexible hours$144.65k - $216.97k
...experienced and visionary Associate Principal Scientist to lead Biologics AI innovation at... ...that integrates state‑of‑the‑art machine learning with wet‑lab discovery to accelerate biologics... ..., risk, and scientific insights to senior stakeholders; influence portfolio decisions...Temporary work- ...every day. If you are a highly curious formulation expert looking to shape a rapidly growing industry, we want you as a Senior Materials Scientist. The Job: Conduct research and develop world-class materials for 3D printing from initial lab explorations to validation...SeniorWork at officeFlexible hours
$70k - $113k
...Summary The Wainger Laboratory at Massachusetts General Hospital (MGH) is seeking a highly motivated, collaborative, and innovative Senior Scientist to lead high-impact translational research at the intersection of neurodegenerative diseases, stem cell biology, functional...SeniorRemote workShift work- ...Senior Research Scientist We are looking for a world-class Senior Research Scientist to join our R&D hub in the Boston area. In this role... ...: PhD or Master's degree in Computer Science, Machine Learning, Robotics, or a related field, with a focus on Deep Learning...SeniorWork at office
$138.6k - $257.4k
...seeking a highly motivated and experienced scientist to lead a small group of biologists with... ...Role Internal Job Title: Senior Principal Scientist/Associate Director... ...days, holidays and other leaves. To learn more about the culture, rewards and benefits...Senior- Moderna seeks a Senior Scientist for the Antibody Discovery team in Therapeutics Research. The role emphasizes protein and antibody engineering... ...biology teams, and guide iterative design‑build‑test‑learn cycles to advance differentiated antibody therapeutics toward...Senior
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Senior Machine Learning Scientist, Climate & Hydrology. Be the first to apply!
- safety scientist Cambridge, MA
- graduate scientist Cambridge, MA
- remote scientist Cambridge, MA
- research scientist - biology Cambridge, MA
- scientist 1 Cambridge, MA
- genomics scientist Cambridge, MA
- research scientist Cambridge, MA
- scientist ii Cambridge, MA
- manufacturing scientist Cambridge, MA
- pharmaceutical scientist Cambridge, MA



