Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Senior Director, Program Lead

$226.2k - $310k

Deciphera Pharmaceuticals

Company DescriptionDeciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera is leveraging its proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates from Deciphera’s platform in clinical studies, QINLOCK (ripretinib) is Deciphera’s switch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. ROMVIMZA (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability. The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability—empowering individuals to challenge the unknown together. Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.Job DescriptionRole Summary: Deciphera’s cross-functional program teams drive the strategy and operations of our late preclinical, clinical, and commercial assets. We are seeking a dynamic, seasoned Sr Director, Program Lead (PL) who will be responsible and accountable for one or more therapeutic assets. The successful candidate will be a strategic leader who can leverage their strong drug development expertise, EQ, and organizational skills to develop and drive the asset strategy and for leading all development and life-cycle management projects associated with the asset. Key attributes of the successful candidate include:Key Responsibilities:Program Strategy & Execution Accountability (60%)For a given asset/program, responsible for the development and execution of the overarching global program strategy. The PL leads all research and development activities associated with an asset from approximately nomination of lead candidates to the marketplace with full accountability.Drive the development and execution of the strategic plan, appropriately balancing data quality, timelines and costs based on current internal corporate considerations and the external landscape.Lead one or more cross-functional program teams to define program vision, strategy, goals, decision points, investments and areas of risk and associated mitigations and contingencies.Partners closely with the program manager to provide strategic, process and operational leadership to the Program teamIdentifies and communicates risks and appropriate mitigationsLead data-driven decision-making processes to enable timely and objective development decisionsCommunicate (20%)Holistic and confident communication: ensure PT clearly understands expectations from leadership, ensure leadership clearly understands program status, timelines, milestones, risks and mitigationsFocus team efforts on most critical tasks; identify and resolve communication bottlenecksParticipate in Portfolio Strategy Steering Committee meetings as the key representative of the program teamLiaise with relevant stakeholders within the Ono Pharma Group to ensure alignment across entities. Liaise with peers within the Program Leadership and Management function to maintain consistent cross-project standards, ensure aligned strategies, and to determine overlap of competing priorities.Promotes organizational reputation by engaging with internal and external stakeholders and collaborating actively with other Deciphera PLs (20%)PLs are experienced, versatile and strong enterprise leadersPLs are highly collaborative cross-functional leaders who consistently drive top performance and deliver against challenging goalsPLs ensure that risks and challenges are addressed proactively and collaboratively with partner functions, with joint decision making when appropriate to drive, deliver and maximize asset value.PLs are effective in communicating to partners and stakeholders at an appropriate level of detail.Other duties and responsibilities as assigned.QualificationsA minimum of 15 years drug development experience in the biopharmaceutical industry including a minimum of 3 years’ development program leadership experienceSolid understanding of drug development process (steps, functions and their roles, key interdependencies)Strong interpersonal skills, with a proven track record of influencing without authority across a matrixed organizationHighly effective influencer without authority at all levelsBuilds consensus, but identifies a final decision maker / escalates when requiredOutstanding written and oral communicator, able to clearly and accurately express complex ideasDemonstrated ability to be flexible and open to adjusting approaches as new information or circumstances emergeResilient in a fast-paced, rapidly evolving environmentHighly motivated with a "hands on" leadership style - no task is too big or small!Strategic, efficient, organized, and empathetic leader who can zoom both in and outCommitted to driving the program forward to the next strategic inflection point to enable an informed decision for next steps, in line with corporate objectives.Preferred CapabilitiesHas experience managing cross functional teamsLate Phase/commercial experience a plusExperience working with the Alliance and Business Development Teams and understanding the importance of partnershipsExperience with MS office suite (PowerPoint, Excel, MS Teams) required, project management tools (Smartsheet, ThinkCell, MS Project) a plusAdditional InformationDeciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $226,200 - $310,000. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.​Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)EQUAL EMPLOYMENT OPPORTUNITY INFORMATIONDeciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.SummaryType: Full-timeFunction: ScienceExperience level: Mid-Senior LevelIndustry: Pharmaceuticals

Vacancy posted 2 days ago
Similar jobs that could be interesting for youBased on the Senior Director, Program Lead in Waltham, MA vacancy
  • $212k - $333.19k

     ...looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Senior Director, Global Program Lead- Neuroscience in our Cambridge, MA office.At Takeda, we are transforming the pharmaceutical industry through our R&D... 
    Senior
    Minimum wage
    Temporary work
    Work at office
    Local area
    Remote work

    Takeda

    Cambridge, MA
    1 day ago
  • Generate:Biomedicines seeks a Senior Director, Scientific Project Lead, Oncology to steer complex programs from concept through preclinical development, shaping translational strategy and guiding portfolio decisions. The role combines people management with broad leadership... 
    Senior

    Generate:Biomedicines

    Somerville, MA
    5 days ago
  •  ...this role in the next 12 months is to advance our lead in vivo development candidate, EDIT-401, by leading program strategy and driving disciplined, cross-...  ...development. Characterizing Your Impact: As the Senior Director, Program Team Lead you will: Lead the... 
    Senior
    Work at office
    Flexible hours

    Editas Medicine

    Cambridge, MA
    19 days ago
  • $192k - $288k

     ...ensuring platform evolution aligns with long-term business goals and providing technical oversight for foundational work.Prioritize and program manage strategic, non-functional programs (e.g., technical debt, capacity planning, architecture scaling) and specific enterprise... 
    Senior

    Klaviyo

    Boston, MA
    1 day ago
  • $195k - $330k

     ...immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new...  ...are valued, seen, and heard.How you’ll make an impact:Provides program management and matrixed leadership to cross functional R&D Development... 
    Senior

    Kymera Therapeutics

    Watertown, MA
    2 days ago
  • $233k - $285k

    Department: 1420GL - Program ManagementLocation: Waltham, MACompany Overview:Dyne Therapeutics...  ...LinkedIn and Facebook.Role Summary:The Senior Director, Program Management (PM) is a critical...  ...role. Primary Responsibilities Include: Lead the operations of one or more high... 
    Senior
    Temporary work
    Work at office
    Local area
    Remote work
    Shift work

    Dyne Therapeutics

    Waltham, MA
    1 day ago
  • $192k - $288k

     ...connective tissue between our Infrastructure organization and the rest of engineering, driving the rollout of critical, cross-cutting programs that affect how we build, operate, and secure our platform at scale.You will juggle a high volume of parallel efforts across cloud... 
    Senior

    Klaviyo

    Boston, MA
    2 days ago
  • $195k - $330k

     ...Kymera is focused on building an industry-leading pipeline of oral small molecule...  ...’ll make an impact:Drive end-to-end CMC program management for mid to late-stage programs...  ...15+ years (M.S.) of CMC experience; Sr. Director level requires commensurate additional experience... 
    Senior

    Kymera Therapeutics

    Watertown, MA
    8 hours ago
  • Senior Director, Program Leader, Corporate Strategy At Agios, we are fueled by connections to transform rare diseases. We foster an inclusive, collaborative...  ...to senior leadership, developing mitigation strategies. Lead asset presentations at governance meetings to secure... 
    Senior
    3 days per week

    Kinsley Power Systems

    Cambridge, MA
    4 days ago
  • LifeMine is seeking a Senior Director, Program Management to lead cross‑functional project management across our research, preclinical, and clinical‑stage drug development programs. This role owns program management for our lead asset and relevant follow‑on assets driving... 
    Senior

    LifeMine

    Watertown, MA
    5 days ago
  •  ...Systems Planning and Analysis, Inc. (SPA) in Massachusetts seeks a Chief of Platform Operations to lead the DevSecOps platform and Common Development Environment, enabling rapid, high‑quality integration for Mission Planning Enterprise. You will ensure pipelines, cloud... 
    Senior

    Jobleads-US

    Lincoln, MA
    5 days ago
  •  ...energy kitchen in Watertown, MA. The role is second in command, supporting the Executive Chef in implementing culinary standards and leading the team to deliver exceptional guest experiences. The successful candidate will bring 3+ years of Sous Chef experience, strong... 
    Senior

    emergemarket.com

    Watertown, MA
    2 days ago
  • LifeMine Therapeutics seeks a Senior Director, Program Management to lead cross-functional project management across research, preclinical, and clinical programs. The role owns PM for the lead asset LIFE-001 and follow-ons, driving timely execution and risk management across... 
    Senior

    LifeMine Therapeutics

    Watertown, MA
    2 days ago
  • $195k - $330k

     ...immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new...  ...make an impact:Serves as an Immunology Translational Medicine Program Lead on cross-functional project team(s) and develops translational... 
    Senior

    Kymera Therapeutics

    Watertown, MA
    1 day ago
  • Astrion presents a Senior Contracting Program Manager role at Hanscom AFB, MA. The position demands extensive DoD program management experience...  ...citizenship and Secret clearance. Responsibilities include leading contract execution, analysis and recommendations, RFP... 
    Senior
    Full time
    Contract work

    Astrion

    Lincoln, MA
    5 days ago
  • $242.25k - $403.75k

    Job Title: Senior Director, Portfolio Integration Lead - HematologyDescriptionFor candidates seeking to be located at our Stevenage site, this role will...  ...relevant.Key ResponsibilitiesPortfolio Strategy & Cross-Program IntegrationShape the advancement of multiple... 
    Senior
    Full time
    Local area
    Remote work
    Work from home
    Relocation

    GSK

    Waltham, MA
    4 days ago
  • $85.6k - $149.4k

    About the RoleAs a Senior Technology Product Manager - GTM Enablement and Launch Lead, you will play a critical role in ensuring the successful planning, coordination...  ...and aligned.The ideal candidate combines strong program execution skills with sound judgment, clear... 
    Senior
    Full time
    Work at office

    Wolters Kluwer

    Waltham, MA
    3 days ago
  • Mariana Oncology, Inc. seeks an experienced Radiochemist to advance personalized medicine and radiopharmaceuticals in a lab-based role. You will develop and optimize radiolabeling methods for new product candidates, address stability and PK questions, and support in vivo...
    Senior

    Mariana Oncology, Inc.

    Watertown, MA
    5 days ago
  • $210k - $270k

     ...Description Role Summary The Vonjo Core Asset Team (CAT) Lead is a senior cross-functional lead accountable for defining and executing...  ...in myelofibrosis, development of a new indication and global program for VEXAS, lifecycle management (LCM), regulatory and... 
    Senior
    Full time
    Temporary work
    Local area

    Sobi

    Waltham, MA
    6 days ago
  • $124k - $186k

    Senior Program ManagerProduct Operations — Lexington, MA, USMimecast is looking for a Senior Program Manager to drive our new features and products from readiness through market launch. You'll take end-to-end ownership of go-to-market programs for your slice of the portfolio... 
    Senior
    Full time
    Local area

    Mimecast

    Lexington, MA
    1 day ago
  • $130k - $194.95k

     ...find cures for cancer. DESCRIPTION Position Summary The Senior Lead, Business Performance & Continuous Improvement partners with...  ..., business transformation, commercial excellence, operations, program management, consulting, or related fields. ~ Demonstrated... 
    Senior
    Full time
    Temporary work
    Work at office
    Waltham, MA
    5 days ago
  • $242.2k - $363.2k

    Job DescriptionGeneral Summary:The Senior Director, Portfolio & Program Management is a global role within the Program and Portfolio Management (PPM) organization...  ...and Commercialization). The incumbent is expected to lead the application of project management to identify... 
    Senior
    Full time
    Summer work
    Remote work
    Flexible hours
    2 days per week

    Vertex Pharmaceuticals

    Boston, MA
    3 days ago
  • $103.6k - $162.8k

     ...role sits within GTM Operations and serves as the orchestration lead for go-to-market execution — coordinating product launches as well...  ...execution and measurable adoption across a portfolio of GTM programs. Product launches will be a core and recurring part of this portfolio... 
    Senior
    Live in
    Worldwide
    Shift work

    ZoomInfo

    Waltham, MA
    1 day ago
  • $143k - $197k

     ...DescriptionWe are seeking a dynamic Sr. Program Manager, Program Leadership & Management,...  ...Program Teams. In partnership with the Program Lead, the Sr Program Manager will drive...  ...timeFunction: Project ManagementExperience level: Mid-Senior LevelIndustry: Pharmaceuticals
    Senior
    Flexible hours

    Deciphera Pharmaceuticals

    Waltham, MA
    2 days ago
  • Town of Arlington is seeking a Lead Heating, Ventilation and Air Conditioning Technician (HVAC) to maintain and repair HVAC, refrigeration, and energy management systems across town buildings, under the supervision of the Building Automation Manager. Requires a high school... 
    Senior

    petersonschool.online

    Arlington, MA
    3 days ago
  •  ...expanding its external innovation capability, and we're looking for a Senior Director of Search & Evaluation to help shape the future of our...  .... We are seeking a Senior Director of Search & Evaluation to lead strategic sourcing and evaluation of later-stage external clinical... 
    Senior
    Remote work
    3 days per week

    CSL Vifor

    Waltham, MA
    2 days ago
  • The MITRE Corporation in Bedford, Massachusetts, is seeking a Solution Lead Senior Principal (SLSP) to oversee 1-3 projects, driving them through the MITRE Innovation Lifecycle. The role requires strong project leadership and an entrepreneurial mindset to achieve disruptive... 
    Senior

    MITRE Corporation

    Bedford, MA
    2 days ago
  • $119.7k - $222.3k

     ...seeking an enthusiastic and motivated PK Sciences representative to lead the development and use of artificial intelligence (AI) enabled...  ...Scientist II. 4+ years of experience to be considered for Senior Principal Scientist.Extensive and in-depth knowledge of pharmacokinetics... 
    Senior
    Full time

    Novartis

    Cambridge, MA
    3 days ago
  • Systems Planning and Analysis, Inc. (SPA) seeks a Program Manager to serve as the single main point of contact with the U.S. Air Force for...  ..., cybersecurity, training, FMS support, and DevSecOps. The role leads program reporting, risk and opportunity management, subcontract... 
    Senior
    Contract work

    Systems Planning & Analysis

    Lincoln, MA
    1 day ago
  • PineTree Therapeutics in Cambridge, MA, seeks a Director of ADC & DAC to lead end-to-end conjugate programs. This role focuses on defining linker‑payload and conjugation strategy, aligning with IND‑enabling activities, and guiding cross‑functional teams to technical milestones... 

    Pinetree Therapeutics, Inc

    Cambridge, MA
    2 days ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Senior Director, Program Lead. Be the first to apply!