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Director, Operational Effectiveness

$121k - $145k

The Director, Operational Effectiveness serves as the primary Syneos Health operations point of contact for a designated customer account, with end-to-end responsibility for operational governance, process stewardship, enterprise coordination, and strategic alignment in support of account leadership objectives. This role provides overarching operational oversight and accountability, ensuring consistent execution, effective decision making, and seamless cross functional collaboration across the organization.

The Director holds significant individual responsibility for leading operational governance forums, stewarding standardized and scalable processes, and coordinating enterprise-wide resources. The role requires close partnership with Syneos Client Services and Operations—including Technology Platforms & Services, Strategic Operations & Analytics, Data Reporting, Technical Training, CRM Solutions, and Incentive Compensation—as well as Syneos Shared Services such as Finance, Human Resources, Compliance, Commercial, Quality Excellence, and Training, Education & Development.

By driving data driven insights, governance rigor, and proactive risk management, the Director ensures operational alignment across internal teams, customer priorities, and broader Syneos initiatives. The role also contributes meaningfully to strategic planning efforts, translating enterprise capabilities into integrated, customer specific operational solutions.


Success in this role requires strong relationship management, exceptional communication skills, deep institutional knowledge, and the ability to navigate complex, matrixed environments involving both internal and external stakeholders.


This role reports to the Syneos Innovative Operations Services (IOS) National Program Director (NPD).

Key Responsibilities

Relationship & Stakeholder Management

  • Relationship management with customer account and maintaining a strong, collaborative relationships with customer and Syneos partners; this includes issue identification and internal Syneos coordination to quickly address. 
  • Balance independent ownership of operational responsibilities with ongoing collaboration across Client Services, DS Operations, and Syneos Shared Services to ensure consistent communication and execution.
  • Operational governance oversight and process stewardship. Participate in customer account operational and client specific meetings and /Syneos Governance sessions to maintain visibility into enterprise-level initiatives.
  • Provide support to the customer account leadership team with preparation and participation with client business reviews, anticipate and mitigate risks, and provide analytical insights to support go-to-market strategies. 

Business Performance & Analytics

  • Collaboration with Syneos customer account leadership (SR VP, NPD) to create the roadmap to commercialization and lead the product strategy for asset management.
  • Data-driven decision-making, partnering with analytics teams for insights, and developing reports, dashboards and summaries for leadership and client use for leadership.
  • Partner with operations analytics teams to derive actionable insights and highlight performance drivers.

Operational Governance & Institutional Knowledge

  • Maintain comprehensive institutional knowledge of the customer account processes, systems, and governance expectations, serving as a central resource for internal teams.
  • Lead the development, documentation, and refinement of operational processes in partnership with relevant Syneos functions, including client-ready presentations and reports that communicate complex information clearly, concise and visually.

Project Tracking & Enterprise Coordination

  • Collaboration with NPD for customer account and Syneos stakeholders in reviewing project readiness, and enterprise-level updates to include MSA revisions, SOW/CO/Amendments/POs, QBRs, audits and business rule document/ways of working changes.
  • Assist in execution of all aspects of significant contract changes, including size and structure. Support business development by contributing to proposals, scoping documents to include hours vs actuals and pricing and thought leadership content.
  • Manage overarching deliverables, ensuring alignment across multiple teams and escalation pathways beyond CSM-level oversight.

Compliance Processes

  • Manage Compliance processes oversight- Eligibility Submissions for client field teams to be supported in Syneos systems, to include onboarding & offboarding. 
  • In coordination with Syneos Compliance, participate in the joint Compliance quarterly submissions and support adherence to compliance standards across all workstreams.
  • In partnership with Syneos Client Services and Compliance, ensuring proper documentation, communication, and internal Syneos auditing.

Technology & Systems Liaison

  • Act as the primary liaison between customer and Syneos Operational teams for technology updates impacting customer accounts and Syneos teams, including major system upgrades, implementation of new tools or platform and transitions/closeouts of systems (CRM)

Success Factors

  • Strong relationship-building skills and the ability to operate confidently with senior stakeholders.
  • High attention to detail, especially in governance, documentation, and compliance-driven processes.
  • Ability to manage multiple concurrent workstreams with clarity, structure, and proactive communication.
  • Comfort navigating ambiguity and driving alignment across diverse teams and functions.
  • Demonstrated ability to balance independent accountability with collaborative execution across Syneos Client Services, Operations, and Shared Services.

Required Qualifications

  • Bachelor’s degree in Business, Marketing, Life Sciences, or related field (MBA preferred).
  • 5+ years of experience in client services, account management, operations, commercial pharma, or related environment.
  • Strong analytical skills with the ability to interpret complex data and develop insights.
  • Excellent communication, presentation, and stakeholder management abilities.
  • Demonstrated success in project management and cross-functional collaboration.

The annual base salary for this position ranges from $121,000 to $145,000. The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate’s qualifications, skills, competencies, and proficiency for the role. In addition, some positions may include eligibility to earn commissions/bonus based on company and / or individual performance.

At Syneos Health, we are dedicated to building a diverse, inclusive and authentic workplace. If your past experience doesn’t align perfectly, we encourage you to apply anyway. At times, we will consider transferable skills from previous roles. We also encourage you to join our Talent Network to stay connected to additional career opportunities.

Why Syneos Health? We partner with industry experts to solve and execute against today’s toughest commercialization challenges facing the world’s leading healthcare companies. The diversification and breadth of our new and existing partnerships create a multitude of career paths and employment opportunities on our Commercial Operations and Leadership teams. Join our game-changing, global company dedicated to creating better, smarter, faster ways to get biopharmaceutical therapies to patients. Experience the thrill of knowing that your everyday efforts are contributing to improving patients’ lives around the world. 

W o r k H e r e M a t t e r s E v e r y w h e r e | How are you inspired to change lives?

Syneos Health companies are affirmative action/equal opportunity employers (Minorities/Females/Veterans/Disabled)

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position will include a competitive compensation package, Health benefits to include Medical, Dental and Vision, Company match 401k, flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos Health complies with all applicable federal, state, and municipal paid sick time requirements.

Vacancy posted a month ago
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