Postdoctoral fellow

The laboratory of Dr. Han-Yu Shih at the National Institutes of Health (NIH) in Bethesda, MD is seeking a motivated and talented postdoctoral researcher to join our multidisciplinary team.Our lab focuses on understanding the mechanisms that precisely regulate gene expression in neuroinflammationand neurodegeneration, with a particular interest in cytokine-mediated CNS inflammation. We use cutting-edge genomic approaches to address three fundamental questions: How do cytokines drive the progression of neurodegenerative and neuroinflammatory diseases in the CNS? How do innate lymphoid cells (ILCs) integrate neuronal signals to support immune adaptation in tissues? How do the microbiome and microbial metabolites regulate lymphocyte differentiation and function during aging-related disorders? The successful candidate will use "omic" approaches to investigate immunoregulation and identify potential therapeutic targets.You will have the opportunity to lead and co-lead projects, design experiments for generating high-dimensional data(single cell transcriptomes and epigenomes, spatial transcriptomes, TCR/BCR repertoires), and work closely with collaborators and lab members. Additionally, you will receive hands-on training in bioinformatics and have opportunities to mentor postbacs or summer students. will be available based on interest. Salary is commensurate with research experience and accomplishments. We are seeking highly motivated candidates who meet the following requirements: Hold a Ph.D. or M.D./Ph.D. in immunology, neuroscience, genetics, molecular biology, biochemistry, computational biology or a related field, awarded within the last three years; Have first authorship on at least one peer-reviewed publication; Possess self-motivation and a strong desire to develop and learn cutting-edge technologies and genomic data analysis; Preferred experience in animal experiments or iPSC/organoid culture; Ability to work collaboratively within a highly cohesive group is important.