Senior Manager, Program Management

Founded over a decade ago, CRISPR Therapeutics is a leading biopharmaceutical company focused on developing transformative gene-based medicines for serious human diseases. The Company has evolved from a pioneering research-stage organization into an industry leader, marking a historic milestone with the approval of CASGEVY (exagamglogene autotemcel [exa-cel]), the world's first CRISPR-based therapy, approved for eligible patients with sickle cell disease and transfusion-dependent beta thalassemia. CRISPR Therapeutics is advancing a broad and diversified pipeline across hemoglobinopathies, cardiovascular, autoimmune, oncology, regenerative medicine and rare diseases. The Company continues to expand its leadership in gene editing through the development of SyNTase™ editing, a novel and proprietary gene-editing platform designed to enable precise, efficient, and scalable gene correction. To accelerate and expand its impact, CRISPR Therapeutics has established strategic collaborations with leading biopharmaceutical partners, including Vertex Pharmaceuticals. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Boston, Massachusetts and San Francisco, California.
Position Summary

The successful candidate will play a critical role in achieving outcomes for our R&D programs. This person will join a strong program management team in the Boston, MA facility driving the success of R&D development teams. The individual will work collaboratively with the program teams and will manage and integrate the diverse drug development activities in key areas that include discovery, preclinical research, CMC and clinical manufacturing, regulatory affairs, clinical development, commercial, program strategy and finance. This is an exciting and interdisciplinary role for a highly qualified and motivated individual. The successful candidate will be a confident program manager, with attention to detail and significant prior success in preclinical and early clinical stage program management for therapeutic programs in the biotechnology industry. The ideal candidate will be detail driven and have a proven track record in managing and driving program success. The successful candidate will also have a solid scientific understanding of the biology of genome editing technologies, as well as the development of cell and gene therapies. We are seeking someone with a sense of urgency for developing important new therapies for devastating diseases and who is interested in forging new and uncharted paths for patients with the exciting CRISPR technology.
Responsibilities

Drives program team(s) and is responsible for working closely with Program Leader and program team members to manage the operational aspects of the program(s), including developing overall strategy, tactical implementation plans, fully integrated program plan and timelines, and monitoring key milestones and decision points to drive delivery of program objectives
Drives team objective setting, prioritization, and tracking ensuring adherence to plan and strategy
Ensures cross-functional alignment and organizational support for the program plan and timelines by facilitating internal and external stakeholder management
Implements project plan flawlessly; optimizes and tracks progress of project plans (time, resources)
Interfaces and coordinates with relevant functional groups to ensure timely execution of program activities including anticipating and identifying program risks, mitigations and contingencies, and supporting timely action plans and issue resolution
Drives issue identification and resolution and leads contingency planning for program team
Ensures effective, proactive, and open communications, horizontally and vertically, in order to achieve transparency and clarity of program goals, progress, and issues, and, where necessary, engages line function management, other internal stakeholders and external experts to overcome obstacles
Represents program to Senior Management; ensures effective communication to align program activities with corporate strategy, and ensure effective program execution
Identifies and resolves conflicts at program team and functional team level
Fosters a culture of ownership and single point of accountability with clear timelines, as well as ongoing evaluation, recognition and process improvement
Is attuned to team dynamics and focuses on team needs directly and/or in partnership with other organizational leaders to ensure optimal team effectiveness
Focuses operations to deliver results by influencing team members beyond existing benchmarks and their own expectations
Leads ad-hoc cross-functional task forces and day-to-day operations of program team
Ensures the development and use of key program management tools including GANTT charts, and the use of management logistics and documentation, by all team members, to enhance program delivery and information dissemination to the team and key stakeholders
Ensures effective program team meetings, logistics and documentation
For programs that are in alliances, drives reporting and program management with collaboration partners
Minimum Qualifications

Degree in the life sciences with at least 3-4+ years of demonstrated program management experience managing cross-functional product development teams
Senior Manager: 10+ Years of relevant experience with a bachelor's degree
8+ Years of relevant experience with an advanced degree
Outstanding leadership and management skills with an integrated view of scientific and product development issues, and demonstrated passion for creating new medicines
Ability to work independently and successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively
Proficiency in project management applications (ex.MS Project, Visio, ThinkCell, MS Timeline) as well as MS Word, MS PowerPoint and MS Excel
Detailed understanding of preclinical and early clinical product development for biologics, and regulatory requirements for IND and CTA filings and First-In-Human clinical trials
Familiarity with cell and molecular biology techniques, LNP delivery
Strong oral and written communication skills, a high degree of energy, accuracy and attention to detail, and a passion for delivering important new medicines to patients with devastating diseases
Preferred Qualifications

PMP certification
Thorough understanding of the preclinical and early clinical development of cell and gene therapy medicines
Experience driving gene editing or cell & gene therapy, LNP & RNA programs
Advanced planning and tracking skills, capable of managing multiple projects with respect to priorities and self-management
Expert in Communication and Information management.
Expert leadership skills demonstrated in program teams,
Expert skills to facilitate/ optimize contributions from team members as individuals and members of a cohesive team
Strong interpersonal and communication skills for bridging between scientific and business participants, for driving a program to effective implementation and for managing effective collaborations; strong verbal communication, expert in written communications, expert team player
Competencies

Collaborative – Openness, One Team
Undaunted – Fearless, Can-do attitude
Results Orientation – Delivering progress toward our mission.
Sense of urgency in solving problems.
Entrepreneurial Spirit – Proactive.
Ownership mindset.
Senior Manager, Program Management: Base pay range of $140,000 to $155,000+ bonus, equity and benefits

CRISPR Therapeutics believes in fostering a dynamic workplace that balances remote work flexibility with the benefits of in-person interactions. Our employees work at least three days on-site, creating a collaborative work environment, where we cultivate mentorship opportunities, increase cross-functional communication and offer opportunities for our employees to connect. Certain lab based and manufacturing positions are located fully on-site.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
Since its inception over a decade ago, CRISPR Therapeutics has transformed from a research-stage company advancing programs in the field of gene editing, to a company with a diverse portfolio of product candidates across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine, cardiovascular and rare diseases.
CRISPR Therapeutics, Inc. is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law.
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