Scientist II, Radiochemistry (preclinical)
$65.31k - $121.28kPerceptive
What can we offer you?Apart from job satisfaction, we can offer you:HEALTHMedical, Dental and Vision benefits for you and your family, including Flexible Spending Accounts (FSA)YOURSELFPaid time off policy including holidays and sick timeInternal growth and development programs & trainingsWEALTH401(k) program, life & accident insurance and disability insuranceThis role offers scientific expertise in reviewing, analyzing, and resolving challenges within the radiolabeling process. Responsibilities include the design and hands-on execution of synthesis, purification, and formulation of radiotracers for use in in vivo imaging, biodistribution, and efficacy studies. The scientist will collaborate closely with cross-functional teams and manage multiple studies simultaneously to support preclinical nuclear medicine programs.Key responsibilities include working safely and compliantly with radioactive materials and operating essential lab equipment such as HPLC and Radio-TLC.Key Responsibilities:Execute and manage the production of radiotracers used in PET/SPECT imaging and therapeutic research studies.Develop and validate:Contribute to the design, development, and optimization of radio labeled compounds targeting complex biological markers for application in PET/SPECT imaging and therapeutic studies.Synthesis of novel PET/SPECT and therapeutic radiopharmaceuticalsPurification methods for small and large moleculesAnalytical methods for HPLC and TLCRelease criteria for imaging studiesDose formulation processesOperate and maintain analytical and automated radiochemistry synthesis units.Stay current on advancements in radiochemistry and imaging through literature review and attendance at scientific conferences.Maintain clear, accurate, and up-to-date records.Analyze data, recognize aberrant results, and propose corrective actions or next stepsSummarize data for reports, papers, and presentations.Manage multiple projects simultaneously and prioritize tasks effectivelyMentor and guide junior team members.Provide scientific expertise and troubleshooting internally and in communication with Sponsors related to radiochemistry.Perform other duties as assigned.Functional Competencies (Technical knowledge/Skills)Experience with small and large molecule radiochemistry labeling, purification, and formulationWorking knowledge and experience with HPLC and TLC techniques in radiochemistryExperience in conjugation with chelators and labeling with radiometals is preferred.Prior experience with F-18 radiochemistry and radioiodination methods is considered advantageous.An effective team player with the ability to collaborate across various departmentsAbility to multi-task different projects and manage time effectivelyStrong written and verbal communication skills that can reach an audience of varying levels of expertiseExperience, Education, and CertificationsPh.D. in Chemistry or relevant field with 3+ years or M.S. with 5+ years of experience in an academic or pharmaceutical labExperience working with radioactive materials in a safe and compliant mannerAbility to lift more than 40 poundsProficient with Microsoft officeEnglish: FluentThis role is based in the Perceptive office/lab located in Needham, MA. The annual base salary range for this role is $65,305- $121,282. This range represents the anticipated initial annual salary and may vary depending on several factors including the candidate’s experience and skills and may be subject to market rate adjustment. #J-18808-Ljbffr Perceptive
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