Senior Scientist I, Biology

Summary Location: Cambridge, MA. This position is located at the Cambridge, MA site and cannot be remote. About the Role The Novartis Biomedical Research Oncology Disease Area is seeking an experienced scientist to join the Target Biology and Discovery (TBaD) group. The mission is to uncover novel therapeutic targets and effective modalities to benefit cancer patients. Key Responsibilities Lead mechanism‑of‑action studies using advanced cell biology and chromatin biology approaches. Design, develop, and execute in vitro assays to elucidate key aspects of cancer biology. Leverage state‑of‑the‑art genome‑editing tools for genetic screens and support compound mechanism‑of‑action studies. Design, execute, analyze, document experiments, and communicate results in team settings. Stay current with scientific literature and advancements. Collaborate across departments and with external partners to foster growth and innovation, and contribute to the culture of the group. Essential Requirements B.S. or M.S. in Biochemistry, Molecular Biology, Cell Biology, Cancer Biology or related field. Experience performing chromatin‑based experiments. Strong proficiency in mammalian cell culture, molecular biology (vector design, cloning), protein analysis workflows (e.g., Western blotting, FACS), and CRISPR‑based gene editing technologies. Clear track record of working efficiently with teams. Strong interpersonal, organizational, and communication skills, with a commitment to fostering a collaborative and innovative work environment. Ability to manage multiple projects simultaneously and deliver high‑quality results. A creative, curious, passionate, and scientifically fearless mindset dedicated to improving the lives of patients. Demonstrates strong critical thinking and independent problem‑solving skills. Desirable Requirements Proficiency with data mining, computational skills, and chromatin‑based analyses. Previous research related to hormone‑driven cancer cell biology (e.g., prostate and breast cancer). Compensation and Benefits Salary range: $93,800 – $174,200 per year (subject to revision). Compensation includes performance‑based cash incentive and eligibility for annual equity awards. US‑based eligible employees receive a comprehensive benefits package including health, life, disability, 401(k) with company match, and generous time‑off. EEO Statement The Novartis Group of Companies is an Equal Opportunity Employer and does not discriminate in employment practices. Accessibility & Reasonable Accommodations Employees requiring accommodations may email View email address on click.appcast.io or call View phone number on click.appcast.io. #J-18808-Ljbffr Novartis ACC