Care Management Liaison, Full Time

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. The Clinical Practice Liaison (CPL) plays a vital field-based role within Madrigal’s Medical Affairs team, focused on improving the standard of care for patients with Metabolic Dysfunction-Associated Steatohepatitis (MASH). The CPL will proactively engage healthcare professionals (HCPs) to provide guideline-based, non-promotional disease education on the identification, diagnosis, and management of MASH.

This role centers on empowering clinical practices to adopt evidence‑based care pathways, integrate non‑invasive diagnostic tools, enhance risk stratification, and collaborate in multidisciplinary care models. The CPL will also serve as a bridge between the medical community and internal Madrigal teams, providing strategic insights that help shape broader corporate understanding and direction. The position reports to the designated Regional CPL (or assigned delegate) and is a field‑based position with travel required within assigned territory.

All incumbents are responsible for following applicable Medical Affairs & Madrigal policies and procedures and are compliant with applicable policies, procedures, and regulations. Strong understanding of US regulations and compliance is required.

Scientific & Clinical Education

Deliver unbiased, evidence-based education on MASH to HCPs based on identified gaps in knowledge or clinical implementation

Present current clinical practice guidelines and real-world data on diagnosis, risk stratification, and patient management

Maintain deep understanding of Non-Invasive Testing (NITs), treatment paradigms, and clinical protocols across the liver/metabolic spectrum

Engage with clinicians, practice managers, and office staff to support implementation of MASH care protocols

Support the integration of guideline‑based approaches into routine clinical workflows and align practices with payer and quality standards

Partner with internal Medical Affairs and Commercial colleagues to address clinical questions and ensure consistent field insights

Contribute scientific expertise to speaker training programs, advisory boards, and internal stakeholder education

Represent Madrigal at national and regional scientific meetings, supporting booth activities and engaging in peer-to-peer exchange

Capture and report actionable insights from clinical practices to inform corporate strategies and educational content development

Compliance & Professional Standards

Adhere strictly to all applicable company and regulatory policies, including FDA and industry guidelines for non-promotional medical engagements.

Ensure thorough documentation and accountability for all scientific interactions.

Maintain a strong understanding of US regulations and compliance

Travel Requirement

Ability to travel up to 70% including support of scientific meetings over weekends

Clinical familiarity with MASH diagnostic tools, especially non-invasive testing and risk stratification methods

S. healthcare system operations, including practice workflows, billing/coding, and payer dynamics

Proficiency in Microsoft Office Suite, virtual communication platforms (e.g., Zoom, Teams), and related Medical Affairs Systems (e.g. Veeva Vault, CRM tools)

Bi-lingual in Spanish

Understanding of industry standards for compliant medical information exchange and field-based scientific roles

Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.