Head of Technical Programme Management

Who we are At Domino, we build solutions that help the largest, highly regulated organizations adopt AI to accelerate mission-critical use cases. Our platform integrates a streamlined model and app development environment, advanced model, agent, and app hosting capabilities, and novel governance capabilities providing regulator-ready AI at scale. Our customers — like Johnson & Johnson, GSK, Bristol Myers, UBS, FINRA and the US Navy — are using our software to solve some of the most important challenges in the world, such as developing new medicines, securing our financial markets, or protecting our country. Backed by Sequoia Capital, Coatue Management, NVIDIA, Snowflake and other leading investors, we have been in business for over a decade but are still a small team operating with the spirit of a startup. In the world of AI today, we believe that the future is still being invented — and we want to be the ones building it. For more information, visit What we are building The Quality and Compliance team at Domino helps teams deliver AI software and solutions with the quality, validation, and supporting evidence that enterprise customers need. We are building repeatable ways to bring these requirements into delivery early and make readiness clear across teams.

We are hiring a Technical Program Manager to own quality and validation readiness across complex programs. You will bring Engineering, Product, forward-deployed engineers, and Customer Success together around clear plans and decisions, and use AI and automation to reduce manual work as our programs grow. Drive quality and validation programs from scoping through readiness review, translating requirements into clear deliverables, owners, milestones, and acceptance criteria.

Coordinate dependencies across Engineering, Product, FDEs, and Customer Success. Resolve blockers and give teams and leadership a clear view of progress, risks, and decisions needed.

Partner with engineering and quality stakeholders to align test coverage, validation evidence, and exception handling. Build repeatable workflows that surface quality and validation needs earlier, prevent recurring issues, and reduce coordination overhead. Use AI and automation in everyday program work. Operate as a highly flexible and adaptable program manager across Engineering & Security when needed on specific cross-functional initiatives driven and agreed upon by the VP, Quality & Compliance, CISO, and/or Head of Engineering.

Approximately 5–8 years in technical program management or a comparable role, with examples of bringing Engineering, Product, and customer-facing teams together to deliver software or technical solutions. You can explain how you established ownership, resolved dependencies, and kept delivery moving across teams you did not directly manage.

You have improved a manual or fragmented process involving testing, validation, release readiness, or customer delivery. You can describe what you personally changed, how teams adopted it, and the resulting improvement in delivery time, quality, rework, or manual effort.

Experience navigating enterprise software delivery . You have worked through shared platform dependencies, customer-specific requirements, and competing engineering priorities. Experience serving regulated customers in life sciences, financial services, or public sector is preferred; You understand software development, automated testing, APIs, integrations, and release workflows well enough to work through implementation tradeoffs with engineers. You have used AI and automation to improve real work and can explain how you checked the outputs and handled failures.

Quality and validation judgment . You can turn a process into actionable Jira requirements, including fields, statuses, dependencies, and reporting, and partner with engineers and administrators to implement it.

Clear communication and customer partnership . You can align internal teams and customer reviewers on deliverables, incorporate feedback, and establish what acceptance requires. You communicate risks early, present practical options, and drive decisions through to completion.

You address immediate delivery needs while improving the processes behind recurring problems. High-performing creative individuals who dig into problems and see the opportunities for success

LI-Remote The annual US base salary range for this role is listed below. For sales roles, the range provided is the role's On Target Earnings ("OTE") range, meaning that the range includes both the sales commissions/sales bonuses target and annual base salary for the role. Additional benefits for this role may include: equity, company bonus or sales commissions/bonuses; medical, dental, and vision benefits;