QC Production Chemist

Production Chemist
Torrance, CA Employment Type: Full-Time

PolyPeptide is seeking a Production Chemist (I, II, and III) to support the manufacture of high-quality Active Pharmaceutical Ingredients (APIs) in a cGMP-regulated environment. These roles are critical to our mission of delivering safe, effective, and on-time pharmaceutical products to patients worldwide.

Whether you are early in your career or an experienced chemist ready to lead, we offer a clear growth path, hands‑on manufacturing experience, and the opportunity to work with advanced peptide synthesis and purification technologies.

As a Production Chemist, you will be responsible for executing and supporting peptide manufacturing operations across upstream synthesis and downstream purification while maintaining strict compliance with cGMP, safety, and quality standards.

Execute batch production records (BPRs) accurately and in compliance with SOPs and GxP requirements

Operate and monitor chemical processes including reactors, drying systems, purification HPLCs, and lyophilization

HPLC, ninhydrin tests)

Ensure proper material handling, inventory management, and ERP documentation following ALCOA+ principles

Communicate effectively with cross-functional teams including QA, QC, Maintenance, Engineering, and Supply Chain

Production Chemist I

Entry‑level to early‑career role with hands‑on manufacturing responsibility

Works under general supervision following established procedures

Focused on execution, learning cGMP operations, and building technical expertise

Ideal for candidates new to peptide manufacturing or regulated production environments

Production Chemist II

Troubleshoots process deviations, supports investigations, and assists with CAPAs and quality documentation

Trains and mentors Chemist I team members

Participates in process improvements, tech transfers, and scale‑up activities

Production Chemist III

Senior‑level chemist and technical leader

Acts as a subject matter expert (SME) for processes and equipment

Makes operational "go/no-go" decisions with Quality and leadership

Leads troubleshooting, process optimization, and mentoring of Chemist I & II staff

Supports production planning, forecasting, and continuous improvement initiatives

Bachelor’s degree in a scientific discipline or equivalent

High School Diploma with significant GMP manufacturing experience may be considered (Chemist I)

Chemist I: 0-2 years of relevant experience (peptide manufacturing preferred)

Chemist II: 3+ years of relevant experience in a regulated environment

Chemist III: 5+ years of relevant experience with demonstrated leadership and technical expertise

Peptide synthesis and purification (HPLC)

Safe handling of hazardous chemicals and reagents

Hands‑on manufacturing environment with hazardous materials

Production Chemist I: $28-$33/hr

Production Chemist II: $33-$37/hr

Production Chemist III: $37-$45/hr

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.

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