Staff Scientist

The Long Lab within the Center for Translational Immunology at Benaroya Research Institute (BRI) is seeking a creative and highly motivated Staff Scientist to investigate the immune mechanisms that drive type 1 diabetes (T1D) and other autoimmune diseases. The Lab combines advanced human immunology, single-cell and multi-modal technologies, and systems immunology approaches to better understand disease progression, patient variability, and response to therapy. Similar approaches are used in the Khor lab that studies Down’s Syndrome and immune aging, presenting a unique opportunity to gain exposure to projects that span immune mediated diseases. This collaborative position provides a unique opportunity to study immune regulation and autoreactive T cell during the earliest stages of T1D using cross-sectional, longitudinal and clinical trial samples. The successful candidate will lead independent cellular and molecular research and will work closely with BRI bioinformaticians and collaborators. This position is equivalent to an Instructor appointment in an academic setting and is ideal for scientists who have completed postdoctoral training and are interested in pursuing an advanced research career outside of the traditional faculty track. Responsibilities Design, lead, and implement multiple complex research projects focused on autoreactive B and T cell biology, immune tolerance, and autoimmune disease. Design and perform experiments to identify autoreactive B and T cells for downstream transcriptional, single-cell, and multi-modal analyses. Analyze, interpret, and document experimental data while maintaining rigorous scientific standards. Use AI and collaborate closely with the BRI Bioinformatics team to integrate computational and systems immunology approaches into experimental design and data analysis. Work collaboratively with investigators across BRI, the University of Washington, TrialNet, and other national and international collaborators. Prepare manuscripts, abstracts, and presentations for publication and scientific meetings. Contribute to the preparation of research grants, fellowship applications, and collaborative funding proposals. Serve as a scientific leader within the Lab by mentoring research technicians, postdoctoral fellows, students, interns, and volunteers. Help establish and optimize new Lab methods and workflows and oversee specialized instrumentation as appropriate. Stay current with advances in immunology, autoimmune disease, and emerging technologies while identifying new scientific opportunities. Foster a collaborative, inclusive learning environment that prioritizes integrity and respect, innovation and agility, and constant scientific inquiry. Qualifications Ph.D. in Immunology or a related biomedical science. Minimum of 3 years of postdoctoral research experience. Experience in tissue culture and cellular and molecular biology techniques. Demonstrated ability to independently design and execute complex research projects through to publication. Strong publication record and evidence of scientific creativity, collaboration, and independent thinking. Excellent written and verbal communication skills with experience presenting scientific findings. Preferred Experience in human immunology, autoimmune disease, or type 1 diabetes research. Experience with flow or spectral cytometry, single-cell technologies, systems immunology, and analysis of large-scale datasets. Experience working with human clinical samples and translational research studies. Familiarity with computational analysis tools and collaboration with bioinformatics teams. Prior experience mentoring trainees and contributing to grant development. Compensation The range is $72,950 to $111,610 annually. Benefits Medical, dental, vision insurance Flexible spending accounts: health care, dependent care, commuter Short and long-term disability Life and AD&D insurance 403(b) retirement plan with matching funds after one year of employment 13 holidays, 3 weeks of vacation and 2 weeks of sick leave per year Employee assistance program Educational assistance program Subsidized ORCA pass Wellness benefits Voluntary benefits About Us Benaroya Research Institute (BRI) has a bold mission: to advance the science to predict, prevent, reverse and cure immune system diseases , from autoimmune disease to cancer to asthma and allergies . We create detailed pictures of the immune system in health and disease, aiming to understand how disorders start and how to rebalance the immune system back to health. Equipped with innovative tools and robust biorepositories , our team chips away at the biggest mysteries behind these conditions to work toward our vision of a healthy immune system for everyone. BRI is a nonprofit research institute based in Seattle and affiliated with Virginia Mason Franciscan Health. We collaborate with clinicians and patients to accelerate the path from innovative lab discoveries to life-changing patient care. Because together, we are powering possibility. To learn more, visit benaroyaresearch.org and connect with us on LinkedIn , Bluesky , Instagram , Threads , Facebook and YouTube. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by state or federal law. If you need an accommodation or assistance completing the online application, please contact Human Resources at View phone number on click.appcast.io or email View email address on click.appcast.io. This contact information is for accommodation requests only and cannot be used to inquire about the status of applications. #J-18808-Ljbffr Benaroya Research Institute