Commercial Affordability Principal Project Manager

The PositionWhy Genentech ​​​​​​​We’re passionate about delivering on Our Promise to improve the lives of patients and create healthier communities for all. We foster a culture of inclusivity, integrity and creativity while boldly pursuing answers to the world’s most complex health challenges and transforming society.Public Affairs & Access (PAA) is a multi-disciplinary organization that includes Corporate Communications; Policy, Evidence & Access Strategy; Channel & Contract Management; External Affairs; Patient Experience; and Strategy and Business Operations. Our purpose is to deliver impact through a fully integrated public affairs function that leverages our capabilities and world-class Genentech brand to deliver on our mission for patients and our employees.The CMG Patient Strategy aims to create a holistic, cross-functional approach to deliver a best-in-class patient experience that aligns with the portfolio, technology tools, and consumer-driven patient expectations in a rapidly evolving business landscape.The Opportunity As the Commercial Affordability Principal Project Manager, you will serve as a key cross-portfolio subject matter expert driving the end-to-end operational execution of Genentech’s commercial affordability programs (including Co-pay, Bridge/Starter, Coupon other patient free goods programs). You can expect to:Own day-to-day operations for multiple commercial affordability programs across diverse brand and therapeutic areas.Manage external vendor performance, driving accountability for SLAs, KPIs, service quality, and complex issue escalations.Lead complex, cross-functional operational initiatives, including program launches, system enhancements, and regulatory updates.Perform root-cause analysis on systemic operational issues and translate insights into scalable portfolio improvements.Interpret program performance data (utilization, access, speed to therapy) to deliver actionable insights and maintain audit readiness.Act as a primary subject matter expert and cross-functional integrator across brand teams, finance, compliance, and Patient Experience (PX).Ensure strict program compliance with regulatory guidelines, internal policies, and operational guardrails.Who you areYou hold a Bachelor’s degree and 5–7 years of relevant experience in vendor management, operations, or project management.You possess strong project management skills with direct experience owning operational processes and driving tactical execution.You demonstrate excellence in communication and presentation skills, with proven ability to effectively engage and educate high-level, diverse audiences on brand and program strategies, translating complex recommendations into clear, actionable guidanceYou have proven experience navigating and adhering to strict regulatory processes and compliance-driven environments.You demonstrate the ability to manage, motivate, and hold external vendors accountable through clear communication and escalation management.PreferredPrior experience within commercial affordability, patient access, in the pharmaceutical or biotechnology sector.Proven track record of cross-functional leadership and influencing without authority within a complex matrixed organization.LocationThis role is based in South San Francisco and offers a hybrid schedule working 3 days per week on campusNo relocation benefits are available for this postingThe expected salary range for this position based on the primary location of CA is $136,100 - 252,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.BenefitsGenentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.Job SummaryJob number: 202608-120287Date posted : 2026-08-05Profession: Business Strategy & DeliveryEmployment type: Full time