Principal Scientist, Embedded ML for Drug Discovery
Flagship Pioneering, Inc.
Flagship Pioneering, Inc. is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational initiatives accelerating pharmaceutical R&D across preclinical to clinical stages. You will define pragmatic AI strategies and oversee method and platform development, leveraging omics, biomolecule design, and literature mining, with agent-based workflows tying methods into end-to-end pipelines. #J-18808-Ljbffr Flagship Pioneering, Inc.
- Pioneering Intelligence is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects across preclinical... ...frameworks, LLM platforms, and agent orchestration to accelerate discovery and translation within Flagship's ecosystem. #J-18808-...Principal
$119.7k - $222.3k
...translation. Experience in late discovery into clinical development is... ...proteins, antibody drug-conjugates, radioligand therapies... ...intelligence (AI) / Machine Learning (ML) approaches to enable model... ..., to be considered for Principal Scientist II. 4+ years of experience to...PrincipalFull time$216k - $297k
...of talented machine learning scientists innovating on model architectures... ...-of-action reasoning, target discovery, perturbation biology, pathway... ...-training, benchmarking, and ML systems.Deep experience in computational... ..., AI-for-biology, AI-enabled drug discovery, translational data...Principal$138.6k - $257.4k
...Research is seeking an accomplished Imaging Scientist to join the Image Analysis team in... ...pathology, computational image analysis, AI/ML, and tissue-based oncology biomarkers.... ...microenvironment biologyExperience supporting oncology drug discovery or early clinical development with image...PrincipalFull time$216k - $297k
Principal ML Scientist, Multimodal Biological Reasoning Cambridge, MA USA The Role Pioneering Intelligence... ...mechanism‑of‑action reasoning, target discovery, perturbation biology, pathway... ...computational biology, AI‑for‑biology, AI‑enabled drug discovery, translational data science,...Principal$119.7k - $222.3k
...translation. Experience in late discovery into clinical development is... ...proteins, antibody drug-conjugates, radioligand therapies... ...intelligence (AI) / Machine Learning (ML) approaches to enable model... ..., to be considered for Principal Scientist II. 4+ years of experience to...Principal- ...accelerate the application of AI and agentic systems across drug discovery. Working at the intersection of Computational Drug Design, project... ...cycle and translate them into scientifically rigorous AI co-scientists that enhance compound design, knowledge synthesis, data...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week
$208k - $286k
..., sustainability, and beyond. THE ROLE We are seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects... ...the frontier: Build and deploy AI/ML that directly powers discovery and decision making across multiple new ventures. Own...Principal- ...expanding the team of talented scientists who seek to build the future of small molecule drug discovery with creativity and innovation... ...Scientist/Senior Scientist/Principal Scientist to lead GPCR protein... ...design tools (e.g., Rosetta, AI/ML-driven prediction)....Principal
$128k - $192k
...to make a real difference, there's only one choice. Principal Machine Learning Scientist The Principal Machine Learning Scientist... ...algorithms and workflows for accelerating early-stage drug discovery. In this role, you are responsible for constructing, studying...PrincipalLocal area$121.28k - $202.13k
...Science is seeking a Translational AI scientist to build ML applications for a long-sought-... .... Experience with deeply embedded in cancer / computational biology,... ...Engineering, Data Science, Datasets, Drug Development, Drug Discovery Process, Drug Target Identification...PrincipalLocal areaRemote workRelocation- ...Looking an innovative Senior Research Scientist - Agentic AI for Drug Discovery to develop next-generation AI... ...role sits within a cutting-edge AI/ML organization focused on building autonomous... ...Vector database solutions Embedding and search pipelines Strong understanding...Full time
$166.77k - $202.09k
...lives. Read more: careers.bms.com/working-with-us. Principal Scientist, AI-Driven Oncology Target Discovery The Informatics and Predictive Sciences (IPS) mission... ...epidemiology and machine learning—across the full lifecycle of drug discovery and development and across all therapeutic...PrincipalHourly payFull timeTemporary workPart timeFor contractorsSummer workLive inWork at officeLocal areaRemote workFlexible hoursShift work$115k - $215k
...targeted proteomics strategies that inform discovery, translational, and clinical-stage decision making within fast-paced drug discovery environments.Development and deployment... ...:Highly organized, solutions-oriented scientist with the ability to manage multiple priorities...Principal- Job DescriptionVertex is seeking an accomplished Senior Principal Scientist with proven record of developing, testing and deploying scientific computational methods and agentic AI systems for drug discovery. In this role, you will work across modalities with emphasis on...PrincipalFull timeSummer workRemote workFlexible hours2 days per week3 days per week
$148.5k - $214.5k
Job title: Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease GenomicsLocation: Cambridge, MAAbout the JobJoin... ...scientists, you will help shape the future of drug discovery and development across Sanofi's therapeutic areas — from early...PrincipalFull time- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...Principal
$126k - $234k
...radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team... ...therapies and advancing the early-stage drug discovery pipeline. This is a labhead-based... ...Lifesciences (Inactive), Machine Learning (ML), Management (Inactive), Medical...PrincipalFull timeRemote work$122.25k - $176.58k
Job title: Principal ScientistLocation: Waltham, MAAbout... ...in the role of Senior Scientist. The Genomic Medicine... ...contributor embedded within the Upstream Scale... ...engages patients early in drug development and uses their... ...the forefront of drug discovery, harnessing cutting-...PrincipalFull time- ...closely with colleagues across Research and Development as a Principal Scientist within Drug Metabolism and Pharmacokinetics (DMPK), providing... ...leadership and strategic guidance to advance programs from discovery through clinical development.Work arrangement: This is an...PrincipalFull timeTemporary workWork at officeLocal areaFlexible hours
$122.25k - $176.58k
Job Title: Principal Scientist, Systems and Disease BiologyLocation: Cambridge... ...that accelerate the path from discovery to patient impact. Ready to... ...to key decision points in the drug discovery process. Opportunities... ...record of data analytics, ML/AI, or computational biology....PrincipalFull time$108.5k - $201.5k
...Summary#LI-OnsiteInternal job title: Principal Scientist ILocation: Cambridge, United StatesWe... ...Requirements:PhD with 2+ years of experience in drug discovery, translational research, or related... ...Management, Machine Learning (ML), Medical Research, Molecular Biology,...PrincipalFull time$176.2k - $277.3k
...and Bioanalytics (PDMB) group is seeking a dynamic, strategic thinking and collaborative Principal Scientist (director-level equivalent) to contribute to our company drug discovery and early clinical development efforts. This position will be based at our research labs...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours- ...in Cambridge, MA, seeks a senior Biomedical Informatics Architect to establish semantic foundations for AI-driven reasoning across discovery, preclinical, and clinical development. You will lead ontology governance, build RDF-based knowledge graphs, and harmonize...Principal
- ...design and evolve AI-ready scientific data products supporting drug discovery and development. You will connect discovery, preclinical,... ...scalable data products and governance. You will partner with scientists, knowledge architects, AI engineers, and platform teams to define...Principal
- ...opportunities. Stay ahead of research and industry trends in oncology drug development, and identify specific areas where the Tempus... ...and illustrate the value of multimodal analysis and AI in drug discovery in coordination with our Research, Engineering & Data Science...PrincipalFull timeRemote workShift work
- ...seeking an experienced, highly motivated Principal Associate Scientist to validate therapeutic gene targets... ...vivo mechanistic studies to support discovery efforts for future RNAi medicines. As... ...under tight deadlines to progress drug discovery efforts.This position is onsiteand...PrincipalFull timeTemporary workWork experience placementLocal areaFlexible hours
$137k - $215.27k
...years of experience in pharmaceutical or biotech setting.Demonstrated experience developing and applying agentic AI systems in drug discovery, including integrating and orchestrating chemical and biological databases, foundation models, scientific software tools, and multi...Minimum wageTemporary workLocal area$168k - $258.5k
...to unlock the future of small molecule drug discovery. FL129 is developing a revolutionary approach... ...and is recruiting a team of top-tier scientists to build this powerful and first-in-... ...with free snacks, coffee, all embedded in a vibrant community of scientists and...$108.5k - $201.5k
...potential to transform patients’ lives around the world. As a Principal Scientist I or II, Oligonucleotide Chemistry and Innovation, you... ..., technical expertise, and innovation to the forefront of drug discovery. Working alongside a collaborative team of world-class scientists...PrincipalFull timeLocal areaWorldwideFlexible hours
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