Principal Scientist, AI for Drug Discovery
Pioneering Intelligence
Pioneering Intelligence is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects across preclinical to clinical R&D. You will define pragmatic AI strategies and oversee cross-functional teams, wiring protein design and omics pipelines with agentic workflows. The role demands leadership, deep ML expertise, and hands-on work with modern frameworks, LLM platforms, and agent orchestration to accelerate discovery and translation within Flagship's ecosystem. #J-18808-Ljbffr Pioneering Intelligence
- Pioneering Intelligence, part of Flagship Pioneering, seeks a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational programs accelerating pharmaceutical R&D across the preclinical, translational, and clinical continuum, working closely with Pioneering...Principal
$119.7k - $222.3k
...of artificial intelligence (AI) enabled strategies to transform... .... Experience in late discovery into clinical development is... ...therapeutic proteins, antibody drug-conjugates, radioligand therapies... ...strategy, to be considered for Principal Scientist II. 4+ years of experience to...Principal$115k - $215k
...targeted proteomics strategies that inform discovery, translational, and clinical-stage decision making within fast-paced drug discovery environments.Development and deployment... ...:Highly organized, solutions-oriented scientist with the ability to manage multiple priorities...Principal$148.5k - $214.5k
Job title: Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease GenomicsLocation... ..., you will help shape the future of drug discovery and development across Sanofi's... ...where deep immunoscience meets bold, AI-powered research. In R&D, you’ll drive...PrincipalFull time$198.9k - $269k
...looking for researchers who aim to build super-intelligent AI systems that leverage proof assistants to guide learning and... ...will join the team at the forefront of this research.As a Principal Applied Scientist, you will play a pivotal role in shaping the definition, vision...PrincipalFlexible hours$126k - $234k
..., CAR-T, and radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team in Cambridge, MA. The... ...evaluating novel cancer therapies and advancing the early-stage drug discovery pipeline. This is a labhead-based position, where the ideal...PrincipalFull timeRemote work$122.25k - $176.58k
Job Title: Principal Scientist, Systems and Disease BiologyLocation: Cambridge,... ...cellular resolution and pioneer AI-powered workflows that accelerate the path from discovery to patient impact. Ready to... ...to key decision points in the drug discovery process. Opportunities...PrincipalFull time$128k - $192k
...difference, there’s only one choice.Principal Machine Learning Scientist The Principal Machine Learning... ...workflows for accelerating early-stage drug discovery. In this role, you are responsible... ...projects with internal and external AI capabilities;Communicate, educate,...PrincipalLocal area$108.5k - $201.5k
Job Description Summary#LI-OnsiteInternal job title: Principal Scientist ILocation: Cambridge, United StatesWe are seeking a motivated soluble... ...Essential Requirements:PhD with 2+ years of experience in drug discovery, translational research, or related field; or Master’s...PrincipalFull time$216k - $297k
...harnessing recent advances in AI, machine learning, and data to... ...of talented machine learning scientists innovating on model architectures... ...-of-action reasoning, target discovery, perturbation biology, pathway... ..., AI-for-biology, AI-enabled drug discovery, translational data...Principal- UCB in Cambridge, MA is seeking a Senior Principal Scientist to lead translational biology drug discovery with emphasis on muscle biology. You will shape in vitro and in vivo models and develop cellular and biochemical assays for early programs across multiple neuromuscular...Principal
$176.2k - $277.3k
...and Bioanalytics (PDMB) group is seeking a dynamic, strategic thinking and collaborative Principal Scientist (director-level equivalent) to contribute to our company drug discovery and early clinical development efforts. This position will be based at our research labs...PrincipalFull timeFor contractorsLocal areaWorldwideFlexible hours$121.28k - $202.13k
...in R&D Translational Science is seeking a Translational AI scientist to build ML applications for a long-sought-after problem... ...Data Analysis, Data Engineering, Data Science, Datasets, Drug Development, Drug Discovery Process, Drug Target Identification, Genetic Analysis,...PrincipalFull timeWork at officeLocal areaRemote workRelocation$114.1k - $211.9k
Job Description SummaryCambridge MAInternal: Principal Scientist I or IILI#-HybridThe Preclinical Safety (PCS) department within the Novartis... ...preclinical safety profiling and assessment for optimal drug discovery, development and commercialization, with state-of-the-art...PrincipalFull timeLocal area- ...seeking an experienced, highly motivated Principal Associate Scientist to validate therapeutic gene targets... ...vivo mechanistic studies to support discovery efforts for future RNAi medicines. As... ...under tight deadlines to progress drug discovery efforts.This position is onsiteand...PrincipalFull timeTemporary workWork experience placementLocal areaFlexible hours
$114.1k - $211.9k
...medicine, molecular biology, or related discipline.7+ years of experience in translational research, biomarker strategy, biomarker discovery, or drug development within the pharmaceutical or biotechnology industry.Demonstrated experience developing biomarker strategies...PrincipalFull timeLocal areaFlexible hours$137k - $215.27k
...changing therapies to patients worldwide.The AI/ML organization at Takeda is building a... ...and machine learning across the entire drug discovery process, not just isolated steps, but as... ...Our team brings together computational scientists, biologists, engineers, and drug hunters...Minimum wageTemporary workLocal areaWorldwide$144.65k - $216.97k
We are seeking an experienced and visionary Associate Principal Scientist to lead Biologics AI innovation at AstraZeneca’s US R&D centers in Waltham,... ...integrates state‑of‑the‑art machine learning with wet‑lab discovery to accelerate biologics engineering and enable next‑...PrincipalFull timeTemporary work$194.1k - $305.6k
...biopharmaceutical company. Our teams combine leading drug discovery capabilities and world‑class R&D with... ...is seeking a talented and experienced scientist to lead the development and deployment... ...in - workflows leveraging generative AI ML - US and Puerto Rico Residents Only:...PrincipalFor contractorsLocal areaRelocationVisa sponsorshipFlexible hoursShift work- ...Scientist-Principal Scientist, Protein Design & Structure Boston, MA Superluminal Medicines... ...to build the future of small molecule drug discovery with creativity and innovation.... ...protein design tools (e.g., Rosetta, AI/ML-driven prediction). Benefits...Principal
$122.25k - $176.58k
...Job title : Principal Scientist ~ Location: Waltham, MA About the Job... ...deep immunoscience meets bold, AI-powered research. In R&D, you... ...engages patients early in drug development and uses their insights... ...at the forefront of drug discovery, harnessing cutting-edge AI,...Principal$138.6k - $257.4k
...Research is seeking an accomplished Imaging Scientist to join the Image Analysis team in... ...pathology, computational image analysis, AI/ML, and tissue-based oncology biomarkers... ...microenvironment biologyExperience supporting oncology drug discovery or early clinical development with image...PrincipalFull time$187.63k - $207.38k
...causing proteins, offering the potential to overcome drug resistance, drug undruggable targets and improve patient... ...is seeking a highly motivated and innovative Principal Scientist in Immunology to lead discovery and translational research for autoimmune and inflammatory...Principal$179k - $200k
...peptide therapeutics and small molecule drug discovery projects from initial hits through to development... ...Familiarity with machine learning and AI-driven platforms in drug discovery.... ...with a talented and passionate team of scientists Be a part of a cutting-edge company...Principal- We are seeking a Senior Principal Scientist to join the US Neuromuscular group based in Cambridge, MA and help drive translational biology drug discovery efforts with an emphasis on muscle biology . This is an opportunity for a scientific leader to advance portfolio projects...PrincipalLocal area
$108k - $128k
...Principal Associate Scientist, Biology Cambridge Parabilis Medicines is a clinical-stage biopharmaceutical... .../β-catenin pathway that has eluded drug developers for decades. Zolucatetide... ...based assay development for oncology discovery programs within our Biology team....PrincipalShift work- ...YouTube. Job Description The Immunology Discovery Therapeutic Area is seeking an accomplished and experienced Scientist to lead the Immune Cell Depletion Group within... ...alongside a strong knowledge of preclinical drug discovery spanning target discovery / validation...PrincipalWork experience placementLocal area
- ...sequencing, immunology, and biologics drug discovery and development. About RA Capital:... ...Therapeutics is seeking an experienced Principal Scientist to help establish and advance our analytical... ...computational sciences, supporting AI/ML-enabled protein engineering and...PrincipalLocal area
- ...Principal Computational Biologist Location: Boston, MA (Hybrid) This is an exciting... ...biology. Working at the forefront of drug discovery, the organisation combines cutting-edge... ...Partner with scientists to design computational strategies that...PrincipalFull time
$160k - $190k
...catenin pathway that has eluded drug developers for decades.... ...including Platform, Data Science and Discovery Sciences to help progress our... ...technical advisor to junior scientists, fostering scientific rigor and... ...Demonstrated ability to utilize AI tools for day-to-day work;...PrincipalShift work
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