Principal Scientist, AI for Drug Discovery
Pioneering Intelligence
Pioneering Intelligence is seeking a Principal Scientist (Embedded ML/Computational) to lead AI/ML and computational projects across preclinical to clinical R&D. You will define pragmatic AI strategies and oversee cross-functional teams, wiring protein design and omics pipelines with agentic workflows. The role demands leadership, deep ML expertise, and hands-on work with modern frameworks, LLM platforms, and agent orchestration to accelerate discovery and translation within Flagship's ecosystem. #J-18808-Ljbffr Pioneering Intelligence
$119.7k - $222.3k
...of artificial intelligence (AI) enabled strategies to transform... .... Experience in late discovery into clinical development is... ...therapeutic proteins, antibody drug-conjugates, radioligand therapies... ...strategy, to be considered for Principal Scientist II. 4+ years of experience to...Principal$168k - $252k
...intelligence and agentic systems in small-molecule drug discovery. This role bridges computational drug... ...science, and engineering to develop AI-enabled workflows that enhance molecular... ...teams to develop and deploy AI co-scientists supporting design, analysis, and lead optimization...Principal$117k - $201.25k
...Johnson & Johnson seeks a Principal Scientist to design an AI-reasoning platform for translational safety in drug discovery. The role focuses on developing multimodal AI systems and agent architectures that integrate scientific data across discovery, preclinical, clinical...Principal$119.7k - $222.3k
...of artificial intelligence (AI) enabled strategies to transform... .... Experience in late discovery into clinical development is... ...therapeutic proteins, antibody drug-conjugates, radioligand therapies... ...strategy, to be considered for Principal Scientist II. 4+ years of experience to...Principal$148.5k - $214.5k
Job title: Senior Principal Scientist Type 2 ImmunologyLocation:Cambridge, MAAbout... ...capabilities, including AI enabled platforms, single cell... ...that engages patients early in drug development and uses their... ...Work at the forefront of drug discovery, harnessing cutting-edge AI,...PrincipalFull time$175k - $225k
...accomplished and highly collaborative Principal Scientist, Biomarker Development, to provide scientific... ..., this individual will support the discovery, development, and implementation of fit... ...biomarker strategies that support drug discovery and preclinical drug development...PrincipalFull time$146k - $236.5k
...:FL117, a venture-backed stealth AI x bio company, is seeking a Sr. Scientist / Principal Scientist, Molecular Simulations.... ...will build the physics layer of a drug development AI platform. You will... ..., at least part of it in a drug discovery setting (Sr. Scientist); 6+ years...Principal- Novartis Institutes for BioMedical Research, Inc. in Cambridge, MA seeks an Imaging Scientist to lead AI-enabled digital pathology and biomarker workflows. You will drive scalable whole-slide image analysis and high-plex tissue imaging strategies across oncology programs...Principal
- ...finally made it possible for AI to impact clinical care in a meaningful... ...at the right time.The Senior Scientist, Applied Machine Learning and... ...Tempus platform supporting drug R&D. The ideal candidate will... ...data analysis or drug discovery/development.Experience working...Full timeShift work
$126k - $234k
...In Vivo Scientist This position is located in Cambridge, MA and does not have the ability to be located remotely. Please only apply... ...novel cancer therapies and advancing the early-stage drug discovery pipeline. This is a labhead-based position, where the ideal candidate...PrincipalRemote work$170k - $200k
...hands-on experience advancing discovery programs from hit identification... ...based and computational-based drug design to optimize peptide and... ...with machine learning and AI-driven platforms in drug discovery... ...and passionate team of scientists Be a part of a cutting-edge...Principal$138.6k - $257.4k
...motivated and experienced scientist to lead a small group... ...enable complex target discovery and validation across disease... ..., the group supports drug discovery projects from... ...Job Title: Senior Principal Scientist/Associate Director... ..., including AI-enabled approaches for...Principal- ...expanding the team of talented scientists who seek to build the future of small molecule drug discovery with creativity and innovation... .../ Senior Scientist / Principal Scientist to lead GPCR protein... ...design tools (e.g., Rosetta, AI/ML‑driven prediction). Benefits...Principal
$126k - $234k
..., CAR-T, and radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team in Cambridge, MA. The... ...evaluating novel cancer therapies and advancing the early-stage drug discovery pipeline. This is a labhead-based position, where the ideal...PrincipalFull timeRemote work$121.28k - $202.13k
...and linkers for ASOs, siRNA, SSO, and RNA editors conjugates, discovery chemistry, and method development. Your expertise will enable us... ...Skills Analytical Chemistry Data Analysis Design Thinking Drug Design Drug Discovery Process Medicinal Chemistry Synthetic...PrincipalFull timeLocal area$148k - $208k
...Your Impact at LILA We're building a talent-dense, high-agency AI safety team at Lila that will engage all core teams within the... ...scientific superintelligence while retaining the core scientific discovery capabilities of the stack. The initial focus of this team will...PrincipalFull timeWork at officeLocal areaFlexible hours$176.2k - $277.3k
...Pharmacokinetics, Dynamics, Metabolism and Bioanalytics - Principal Scientist Our company is a global health care leader with a diversified... ...our company's bioanalytical efforts for biologics in our drug discovery portfolio. -This position will be based at our research...PrincipalFor contractorsLocal areaWorldwideRelocationVisa sponsorshipFlexible hoursShift work$216k - $297k
...harnessing recent advances in AI, machine learning, and data to... ...of talented machine learning scientists innovating on model architectures... ...‑of‑action reasoning, target discovery, perturbation biology, pathway... ..., AI‑for‑biology, AI‑enabled drug discovery, translational data...Principal- 1910 in Boston seeks an experienced computational chemist to lead drug discovery efforts. The ideal candidate will have a Ph.D. and extensive experience in quantum chemical methods and molecular dynamics simulations. This role involves collaboration across interdisciplinary...
- 1910, based in Boston, is seeking a Computational Chemist to enhance drug discovery through innovative computational chemistry solutions. In this pivotal role, you will lead programs across various therapeutic modalities, ensuring collaboration with biology and medicinal...
$108.5k - $201.5k
...potential to transform patients' lives around the world. As a Principal Scientist I or II, Oligonucleotide Chemistry and Innovation, you... ..., technical expertise, and innovation to the forefront of drug discovery. Working alongside a collaborative team of world-class scientists...PrincipalFull timeLocal areaWorldwideRelocation packageFlexible hours$144.65k - $216.97k
We are seeking an experienced and visionary Associate Principal Scientist to lead Biologics AI innovation at AstraZeneca's US R&D centers in Waltham,... ...integrates state-of-the-art machine learning with wet-lab discovery to accelerate biologics engineering and enable next-...PrincipalTemporary work$138.6k - $257.4k
...Research is seeking an accomplished Imaging Scientist to join the Image Analysis team in... ...pathology, computational image analysis, AI/ML, and tissue-based oncology biomarkers... ...biology Experience supporting oncology drug discovery or early clinical development with image...Principal- ...Senior/Principal Scientist, MPN Biology, Translational Sciences Job summary: PharmaEssentia... ...including cytokines, antibodies, antibody-drug-conjugates, cell-based therapies and... ...therapeutics from project conception to late discovery and into first in human clinical trials...PrincipalContract work
$106.38k - $132.98k
...What you’ll need to succeed as a Senior Scientist, Data Science at XPO Minimum qualifications... ..., or data analysis with a focus on AI-driven analytics, statistical modeling, machine... ...required to take and pass a pre-employment drug test. The above statements are not...$168k - $252k
...Vertex Pharmaceuticals seeks a Senior Principal Scientist to develop and deploy agentic AI systems for drug discovery. The role combines computational expertise with scientific leadership to create AI-enabled workflows that enhance small molecule and protein therapeutic...Principal$214.1k - $337k
...Merck seeks a Senior Principal Scientist to lead mass spectrometry capabilities within the Quantitative Biosciences group in... ...strategic leadership, mentorship, and collaboration across discovery programs to advance drug discovery decision-making. Responsibilities...PrincipalLocal area$109k - $174.8k
...the way. Learn more at Position Summary Senior Scientist - Data (AI) Scientist, Translational Safety to join the... ...Medical Officer) organization helping accelerate drug safety prediction across all stages of drug discovery and development, using advanced AI/ML analytics...Work at officeLocal areaImmediate start$176.2k - $277.3k
...Principal Scientist position leading bioanalytical strategies for biologics in drug discovery. The role involves managing a team of scientists, developing ligand binding assays and mass spectrometry methods, and collaborating across immunology and oncology programs at...Principal$144.8k - $217.2k
...seeks a computational chemist to lead drug design initiatives using molecular modeling, cheminformatics, and AI methods. The role involves advancing... ...identification programs, mentoring junior scientists, and collaborating across discovery teams in Boston on a hybrid basis....Principal
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