Head of Sales Reserves & AI Transformation
$191.5k - $355.6kGenentech
The Position
The Head of Sales Reserves & AI Transformation (Director Sales Reserves) leads one of the most high-profile and judgment-intensive functions in Finance. This role is responsible for the financial integrity of over $10 billion in annual Gross-to-Net (GTN) reserves across Genentech's commercial portfolio.
The Opportunity:
Beyond traditional oversight, this leader is the Strategic Architect for the Reserves Digital Evolution. You will lead a "moonshot" project to search for, develop, and implement a cutting-edge AI Tool for analytics, forecasting, and scenario planning. The goal is to move the function from manual, spreadsheet-heavy execution to an AI-augmented model that provides superior predictability and real-time decision support.
Key Accountabilites & Responsibilites:
AI Evolution & Digital Leadership (Primary Focus):
Reserves AI Tool Implementation: Lead the end-to-end search, design, and deployment of a new AI platform to enhance outcomes and scenario modeling.
GenAI & Agentic Workflows: Implement AI-driven chatbots to automatically explain reserve rationale to stakeholders and provide real-time compliance documentation.
Innovation Mindset: Act as a Digital Champion, ensuring your team dedicates upwards of 50% of capacity to digital activities and automation spikes.
Predictive Analytics: Transition the team from historical reporting to predictive insights using machine learning to anticipate the impacts of innovative pricing and government regulation.
Forecasting, Compliance, and Stewardship:
Portfolio Oversight: Ensure the accurate forecasting of >$10B in annual reserve provisions.
Financial Integrity: Verify the adequacy of balance sheet accounts and approve all reserve rates recommended by the team.
Risk & Control: Maintain a best-in-class internal control environment compliant with all FGAR and audit requirements.
Strategic Partnering: Act as an economic advisor to Commercial operational groups, CMG Finance, and Basel HQ on reserve implications for new contracting strategies.
Stakeholder Management:
Key Stakeholders: US Finance Leadership Team (FLT), Commercial Squads, Ecosystem leads, and External Auditors.
Level of Influence: Seasoned in presenting complex financial judgment calls and high-stakes "moonshot" digital narratives to executive leadership.
External Exposure: Primary liaison for external audit regarding one of Genentech's most critical accounting areas.
Leadership Skills & People Management:
Team Development: Lead and develop 4 direct reports, moving them from traditional finance profiles to "Finance Technologists".
Principles: Lead from your seat; foster an environment where team members lead change management during digital transitions.
Who you are:
PL8 & PL9 ( One position but two possible levels based on skills and qualifications).
*People Leader Level 8: skills and qualifications
Experience: 12+ years of relevant financial and business experience.
Education: Bachelor's degree in Business, Finance, or Healthcare Management; MBA preferred.
Domain Expertise:In-depth experience in Pharmaceutical Gross-to-Net sales reserves and a solid understanding of government programs (340B, Medicaid, Part D).
Digital Track Record: Proven experience leading the implementation of digital or AI tools within a complex operational function.
Technical Skills: Proficiency with SAP and TM1 is preferred as we transition toward integrated SAC/AI solutions.
The expected salary range for this position based on the primary location of California is between $161,000-$299,00
People Leader Level 9: skills and qualifications
Experience: 15+ years of relevant financial and business experience.
Education: Bachelor's degree in Business, Finance, or Healthcare Management; MBA preferred.
Domain Expertise:In-depth experience in Pharmaceutical Gross-to-Net sales reserves and a solid understanding of government programs (340B, Medicaid, Part D).
Digital Track Record: Proven experience leading the implementation of digital or AI tools within a complex operational function.
Technical Skills: Proficiency with SAP and TM1 is preferred as we transition toward integrated SAC/AI solutions.
Relocation benefits are not available for this position.
The expected salary range for this position, based on the primary location in California, is $191,500 -$355,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits (
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants ( .
- Job Overview The Head of Sales Reserves & AI Transformation (Director Sales Reserves) leads one of the most high‑profile and judgment‑intensive functions in Finance. This role is responsible for the financial integrity of over $10billion in annual Gross‑to‑Net (GTN) reserves...TransformationLocal areaRelocation package
$161k - $355.6k
F. Hoffmann-La Roche AG is seeking a Head of Sales Reserves & AI Transformation to oversee over $10 billion in annual Gross-to-Net reserves, and drive digital evolution within the finance team. Applicants should have significant experience in financial analysis and digital...Transformation$121.4k - $237.36k
...difference drives change. As inventive transformation consultants, we blend our strategic, creative... ...and market perspectives. As AI reshapes how organizations operate, compete... ...consistent with applicable laws. The Company reserves the right to amend or withdraw...TransformationFull timeLocal area$171.2k - $273k
...Job Overview Salesforce is the #1 AI CRM, where humans with agents drive customer success... ...the business impact of the investment, transforming technical milestones into measurable ROI... ...across matrixed internal teams (Sales, Product, Engineering) to deliver seamless...Transformation- ESP Engineered is looking for a Senior Business Development Manager in San Francisco, USA. This role involves shaping market presence and driving strategic growth within one of our critical markets. You will identify and close high-value opportunities while building relationships...Transformation
$157.5k - $254.35k
...becomes increasingly digital, AI‑driven, and collaborative,... ...Director of Partner Digital Transformation & Success to elevate how partners... ...within Docusign. Docusign reserves the right to change a position... ...eligible for the following: Bonus: Sales personnel are eligible for...TransformationPermanent employmentFull timeContract workWork at officeLocal areaRemote workShift work- ...Delivery and Strategy Lead. This role involves driving the digital transformation strategy and managing the end-to-end design and deployment of S... ...years of experience in S2P/Procurement with a strong focus on AI integration and stakeholder engagement, ensuring a best-in-...Transformation
- Join a dynamic strategy consulting firm dedicated to transforming the high-tech landscape in the Gulf economies. This role offers the chance... ...'ll be at the forefront of digital transformation, utilizing AI to streamline processes and enhance business development efforts...Transformation
- A global biopharma company in South San Francisco is seeking a Director of AI Transformation. The ideal candidate will lead key initiatives focused on AI-driven transformation strategies to enhance business operations, collaborate with executive teams, and mentor high-performing...TransformationRemote work
- A tech company specializing in AI solutions, based in San Bruno, is looking for a Compiler Developer. The role involves building... ...and maintaining model ingestion pipelines, implementing graph transformations, and optimizing execution for a custom ML compiler. Candidates...Transformation
- ...a Compiler Engineer to work on a custom ML compiler for their AI accelerator. The role requires a minimum of 2 years experience... ...responsible for building model ingestion pipelines, implementing graph transformations, and debugging. The position offers benefits including medical...Transformation
- ...within enterprise customers in the United States to drive digital transformation. This role focuses on creating and deploying customized... ...hands-on expertise with relational databases, and familiarity with AI technologies. It's a unique opportunity to work at the forefront...Transformation
- ...Job Description You will work on a custom ML compiler that transforms modern ML and DSP models into highly efficient programs for our... ...experience: ~2+ years of experience in compilers and/or edge-AI ~ Proficiency in Python and/or C++ ~ Experience with at least...Transformation
$100k
...SMB and large enterprises that are looking to drive Data and AI transformation initiatives. We architect and deliver modular, secure,... ...phase and are seeking an entrepreneurial, sophisticated Head of Sales to design, execute, and scale our commercial engine. This...TransformationFull timeContract workRemote work- A leading software development firm in San Francisco is seeking a VP of Strategy to drive AI-driven digital transformation. You will act as a trusted advisor to C-level executives, defining and leading strategic initiatives that shape modernization efforts. With at least...TransformationRemote job
$330k - $390k
...growing healthcare technology company transforming revenue cycle management (RCM) through AI-driven automation. Millions of... ...are hiring a Director of Enterprise Sales to lead and elevate our enterprise... ..., we confront these challenges head on by running INTO the storm. Core...TransformationRemote work- Agivant is seeking a Principal Solution Architect in the Bay Area to lead AI-driven digital transformation efforts. This high-impact role involves being a primary technical strategist for complex client engagements, focusing on Data Engineering and cutting-edge AI applications...Transformation
$160k - $210k
Redwood Materials, Inc. is looking for a Digital Transformation Lead to define and execute the EPC digital strategy. You will oversee major digital systems while establishing scalable, data-driven processes across design, engineering, and construction. With 10+ years of...TransformationFull time- ...leading technology company is seeking a Director of Partner Digital Transformation & Success in San Francisco. This role involves defining digital transformation strategies for partners, integrating AI-driven experiences, and enhancing partner engagement. Ideal candidates...TransformationRemote work
$226.1k - $266k
...of product data, ensuring efficient operations across design, supply chain, and manufacturing. With a strong focus on digital transformation and operational excellence, this hybrid position requires extensive leadership and scaling expertise, along with a competitive...Transformation- EvoluteIQ AB is seeking a Sales Engineering Lead in San Francisco to engage with enterprise... .... With a focus on innovation and digital transformation, you will lead discussions from discovery... ...pre-sales and a proven track record in AI or automation platforms. Join us in...Transformation
$220k - $225k
...built to power and protect the world at work. With the rise of AI and Agents, the identity perimeter needs to be secured at scale... ...security for the world's leading enterprises. In a world of digital transformation, where organizations are faced with increasing cyber risk but...Transformation- Serval is seeking a Lead Sales Recruiter to build and own the recruiting strategy for our sales teams, aiming to scale from ~70 to 200+ employees while ensuring high talent quality. The ideal candidate will have 6+ years of recruiting experience, especially in high-growth...
- A technology-driven recycling company is seeking a Director of Sales to establish and lead a high-performing sales organization from the... ...7-10 years of experience and a strong knowledge of CRM tools and AI applications in sales. Competitive compensation is offered, including...
- ...Introduction At IBM Software, we transform client challenges into solutions. Building the world's leading AI-powered, cloud-native products that shape the future of business and society. Our legacy of innovation creates endless opportunities for IBMers to learn, grow...TransformationShift work
- ...Senior AI Platform Engineer Locations: San Francisco, CA / Jacksonville, FL / Boston, MA / New York, NY (Hybrid) SS&C Advent... ...'s front-to-back office will be part of the journey to digital transformation, which started with our cloud-native, award-winning Genesis...TransformationCasual workFlexible hours
- ...Introduction At IBM Software, we transform client challenges into solutions. Building the world's leading AI-powered, cloud-native products that shape the future of business and society. Our legacy of innovation creates endless opportunities for IBMers to learn, grow...Transformation
$167.8k
...build, and maintain applications, integrations, and intelligent (AI-enabled) solutions across the technology stack Define the... ...citywide strategies for cloud, cybersecurity, privacy, and digital transformation. Architect the system landscape including data...TransformationFull timeWork experience placementSecond jobWork at officeImmediate start- ...Introduction At IBM Software, we transform client challenges into solutions. Building the world's leading AI-powered, cloud-native products that shape the future of business and society. Our legacy of innovation creates endless opportunities for IBMers to learn, grow...Transformation
- ...A dynamic AI solutions company located in San Francisco is looking for a Head of Enterprise Sales to own and scale the enterprise revenue engine. In this role, you'll lead pipeline generation, develop sales processes, and close significant deals with AI labs and startups...Remote workFlexible hours
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Head of Sales Reserves & AI Transformation. Be the first to apply!
- finance transformation jobs South San Francisco, CA
- sales recruiter South San Francisco, CA
- sales South San Francisco, CA
- route sales driver South San Francisco, CA
- in home sales South San Francisco, CA
- global sales South San Francisco, CA
- sales marketing work from home South San Francisco, CA
- sales - training offered South San Francisco, CA
- business to business sales South San Francisco, CA
- legal sales South San Francisco, CA


