Scientist, Membrane Protein Biochemistry
Initial Therapeutics, Inc.
Join Amgen's Mission of Serving Patients At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission to serve patients living with serious illnesses drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award‑winning culture is collaborative, innovative, and science‑based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientist, Membrane Protein Biochemistry What you will do Lets do this. Lets change the world. In this vital role you will design strategies for recombinant production of polytopic membrane protein (MP) targets and purify MPs into stable formulations with detailed analytical characterization. This role will also include opportunities to develop capabilities that increase the success rates of large‑molecule and small‑molecule therapeutic discovery programs. This is an onsite laboratory position at our South San Francisco site. Key Responsibilities Independently devise and implement state‑of-the‑art membrane protein production strategies through conducting laboratory experiments with rigorous documentation and emphasis on quality of deliverables Analyze and interpret scientific data with the intent to communicate results to audiences with diverse scientific backgrounds Collaborate with other scientists to plan methodological approaches, necessary resources, timelines, and milestones to drive defined projects forward Additional responsibilities include keeping current in membrane protein expertise to advise supervisors and colleagues on future membrane protein technology development strategies What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Scientist we seek is a Researcher with these qualifications. Basic Qualifications Ph.D. in Biochemistry, Biophysics, Chemistry, Molecular Biology, or a related discipline Masters degree and 2 years of relevant laboratory experience Bachelors degree and 4 years of relevant laboratory experience Preferred Qualifications Ph.D. plus 0‑2 years of relevant postdoctoral experience Demonstration of independent design, execution, and interpretation of experiments and results, as exemplified by a solid publication record with first‑author publication(s) Proven expertise with KTA systems and analytical methods for membrane protein characterization using quality‑focused analytical methods such as HPLC/UPLC (SEC, fSEC), spectroscopy, or mass spectrometry. Proven expertise in structural biology or dissection of MP molecular pharmacology is a plus Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams in a fast‑paced environment What you can expect from us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we support your journey every step of the way. A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan Stock‑based long‑term incentives Award‑winning time‑off plans Flexible work models where possible Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. #J-18808-Ljbffr Initial Therapeutics, Inc.
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