Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research Center

Position Summary Senior Principal Scientist (Discovery Biology) – Immunologist and leader to shape T cell engager and cancer immunology therapy strategy; drive projects from concept to clinic in Seattle, WA; mentor junior scientists and lead multi‑functional teams. Position Responsibilities Lead matrixed TCE/cancer immunology discovery teams from target concept to IND; lead/mentor a biology team supporting in vitro experimentation. Deploy existing and new techniques for function‑based identification and selection of lead drug candidates. Leverage experience to shape overall strategy and inform next‑wave therapeutic innovation. Collaborate with functional area leads (e.g., pharmacology, DMPK, bioinformatics) to drive programs, define priorities and risks. Collaborate with multidisciplinary external partner teams to advance assets. Present complex concepts to governance and project meetings; use strong communication and interpersonal skills (email, meetings, reports). Basic Qualifications Bachelor’s + 10+ years academic and/or industry experience; or Master’s + 8+ years academic and/or industry experience; or Ph.D./advanced Life Sciences + 6+ years academic/industry experience; 2+ years leadership experience. Preferred Qualifications/Skills Industry experience; 2+ years leadership. Experience developing novel cancer immune therapeutics (T cell redirected therapies). Profiling/developing complex biologics to enhance tumor microenvironment immune function; strong T cell engager discovery. High‑throughput screening and complex cell‑based assays; interpret in vivo functional assays. Lead/collaborate across matrixed discovery programs from concept to IND; contribute to an IND. Ability to manage multiple projects; summarize complex data clearly; lead/coach lab‑based in vitro biologists; excellent oral/written communication; governance communication; problem‑solving; leverage AI for strategic/tactical planning. Benefits Health coverage (medical, pharmacy, dental, vision); wellbeing support programs; financial protection (401(k), disability, life insurance, etc.). Paid time off: flexible time off (unlimited) for US exempt employees; or 160 hours annual vacation + paid holidays for specified roles. Application Instructions If interested but not a perfect resume match, apply anyway. #J-18808-Ljbffr Bristol Myers Squibb