Director, Global Medical Lead, Zasocitinib - Psoriatic Arthritis (PsA)

Objectives: Accountable for development, implementation, and ongoing optimization of the global medical strategy for zasocitinib in PsA. Provide Director-level medical leadership and strategic counsel on product profile, data interpretation, benefit-risk, evidence gaps, and external scientific dynamics. Lead the global PsA Medical Strategy Team; coordinate medical sub-teams and matrix partners for integrated, timely execution. Define the medical evidence and scientific communications plan; translate insights from patients, HCPs, and external experts into action. Enable global-to-local medical strategy deployment with regional/affiliate medical teams while considering local practice, access, regulatory, and stakeholder needs. Model scientific excellence, inclusive collaboration, compliance, accountability, and patient focus; mentor matrix colleagues. Accountabilities: Global medical lead and single-point medical accountable leader for zasocitinib in PsA (reporting to GMUH, Rheumatology). Partner to define and execute a multi-year global medical vision, integrated strategy, and evidence plan across the PsA lifecycle. Translate PsA science, patient unmet need, and stakeholder insights into medical priorities (launch preparedness, evidence generation, scientific communications, lifecycle opportunities). Lead a global cross-functional medical matrix across Clinical Development, Regulatory, Pharmacovigilance, Commercial, Market Access, HEOR, DD&T, regions, and affiliates. Chair/lead MST workstreams; provide medical recommendations, risk assessments, and decision input to GPT and governance forums. Establish strategic priorities/milestones/KPIs; monitor execution, resolve barriers, and elevate risks. Act as scientific steward for scientifically rigorous, compliant, patient-centered content and engagement; oversee evidence-generation strategy (RWE, investigator-sponsored research, partnerships, publications). Build relationships with thought leaders, societies, patient advocacy groups; represent Takeda in high-impact forums. Provide senior medical review/approval input for scientific and promotional/non-promotional materials; manage medical/evidence/safety/regulatory/reputational risks. Champion responsible use of digital/data science/AI to strengthen insight generation and patient/HCP experience. Education/Experience & Qualifications: Required: advanced scientific/clinical degree (MD, DO, MBBS, PharmD, PhD, or equivalent). Strongly preferred: rheumatology/immunology/dermatology specialist experience. Typically 8-12+ years in biopharmaceutical medical affairs, clinical development, or related; meaningful global/regional strategic leadership. Strong experience leading medical strategy/execution in a matrixed organization; pre-launch/launch and/or lifecycle-management preferred. Proven expertise in rheumatology, immunology, and/or psoriatic arthritis. Required: evidence generation, publications, scientific communications, external expert engagement, global medical governance. Working knowledge of global pharmaceutical laws, regulations, and industry medical/commercial boundary requirements. Preferred: digital/analytics/AI-enabled approaches. Skills: Strategic and enterprise mindset; ability to interpret clinical/safety/RWE/competitive data and communicate clearly to technical/non-technical audiences. Ability to influence senior stakeholders in a global matrix; judgment/integrity in regulated environments. Strong partnerships with external experts and internal cross-functional leaders; business/operational acumen. Exceptional written/verbal/presentation/executive communication across cultures. Commitment to patient centricity, inclusion, scientific excellence. Benefits: U.S. based employees may be eligible for medical, dental, vision, 401(k) match, disability, life insurance, tuition reimbursement, paid volunteer time off, holidays, well-being benefits; up to 80 hours sick time and up to 120 hours paid vacation for new hires. #J-18808-Ljbffr Scorpion Therapeutics