Principal Scientist - In Vitro Immunotherapy
$126.9k - $215.4kMillipore Corporation
Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. Your Role: Help to shape next generation cancer immunotherapies at EMD Serono. Key Responsibilities: Provide creative, strategic input-conceive new project ideas and help design execution-ready workplans Drive early drug discovery projects in immuno-oncology by designing, conducting and overseeing in vitro/ex vivo pharmacology studies (human immune cell / tumor cell co-culture assays; profile function via flow cytometry, cytokine/biomarker readouts, and high-content imaging) to support development of novel biological and small molecule agents Build and validate human immunology models that complement animal studies to improve translational predictivity and de-risk candidates Scout, implement, and champion new assay platforms to investigate novel MOAs, boost data quality, throughput, and decision-making speed Independently generate in vitro data for target selection, lead optimization, candidate nomination; and enable program decisions toward IND-enabling studies Analyze, document, and present results to multidisciplinary teams and senior leadership; manage studies at CROs and academic collaborations where needed Who You Are Minimum Qualifications Bachelor's degree with 8+ years of experience, or Master's degree in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 5+ years of hands-on immunology/immuno-oncology (T-cell biology) experience in academia or industry setting ORPhD in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 2+ years post-PhD of hands-on immunology/immuno-oncology (T-cell biology) experience in academia or industry setting. Preferred Qualifications Experience with driving early drug discovery projects and leading cross-functional teams Expertise developing, running complex T-cell functional assays (activation receptors, costimulatory molecules, checkpoint receptors) and interpreting mechanistic data to inform early development Experience in designing, executing, and interpreting in vitro assays for drug discovery, including tumor models and pharmacology experiments Clear, crisp communicator; highly organized multi-tasker who adapts quickly to deliver on-time data packages Confident influencer who engages senior leadership and thrives in a matrixed organization Proven scientific impact-publications and contributions advancing new therapeutic concepts Pay Range for this position $126,900 - $215,400 Benefits offered by the Company Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. Direct link to benefits site if the hyperlink no longer works: Our Culture We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress! #J-18808-Ljbffr Millipore Corporation
- EMD Serono seeks an experienced immunologist to help shape next-generation cancer immunotherapies. You will drive early drug discovery with human immune and tumor cell assays, build translational models, and guide cross-functional teams to IND-enabling decisions. The role...Suggested
- EMD Serono, Inc. is seeking an In Vitro Principal Scientist to shape the in vitro strategy for tumor immunology initiatives. You will execute experiments and lead discovery teams, coordinating across oncology projects to advance candidates through early development. The...Suggested
- ...Senior/Principal Scientist, MPN Biology, Translational Sciences PharmaEssentia Innovation Research Center (PIRC) is seeking a highly motivated... ...: Oversee the analysis, interpretation, and reporting of in vitro and in vivo pharmacology/translational biomarker data,...PrincipalContract work
- PharmaEssentia Innovation Research Center (PIRC) seeks a Senior or Principal Scientist in myeloproliferative neoplasm biology to advance translational pharmacology and MOA studies for BESREMi and other therapeutics. You will design and execute POC/translational studies,...Principal
$126k - $234k
...cancer patients through a combination of treatment approaches including targeted therapies, immunotherapies, CAR-T, and radioligand therapy. NIBR is seeking an in vivo scientist to join our Oncology Pharmacology team in Cambridge, MA. The successful candidate will join...PrincipalFull timeRemote work$142.5k - $256.5k
...to provide technical leadership for in vitro selection and cell-surface screening of... ...discovery resource. This role is intended for a scientist ready to own and evolve a core discovery... ..., and ownership consistent with a Principal Scientist role. Here’s What You’ll...PrincipalPermanent employmentFull timeWork at officeWork from home$179k - $236k
...closely with world-class computational biologists, machine learning scientists, experimental biologists, chemists, clinicians , and... ...associated states in cell atlases, guide development of the in vitro and in vivo systems that model them, use our single-cell AI models...PrincipalFull timeShift work$142k - $215.2k
...working culture, presenting great opportunities for personal development and career advancement across the globe. Your Role The Principal Scientist, Translational Quantitative Pharmacology (TQP) position in Quantitative Pharmacology within the broader Clinical Measurement...PrincipalFlexible hours- Generate Biomedicines is seeking a Principal Scientist to lead Target Binding within our Protein Analytics & Biophysics (PAB) department. This role combines hands‑on technical work with strategy, cross‑functional program leadership, and mentoring of junior scientists. The...Principal
- ...programs in therapeutic areas where weekly or monthly doses would improve adherence and health outcomes. Summary of Position The Principal Scientist - Formulation is an experienced scientific leader who will lead Nortiva’s Formulation Team. Nortiva’s novel ultra-long-acting...PrincipalLocal area
$122.25k - $176.58k
...Job title : Principal Scientist ~ Location: Waltham, MA About the Job The Genomic Medicine Unit (GMU) CMC group at Sanofi is dedicated to the establishment of best-in-class manufacturing platforms to support development of life-changing advanced cell...PrincipalFull time$108.5k - $201.5k
...Job Description Summary As a Principal Scientist, you will lead and execute formulation development and characterization strategies for complex biologics—including monoclonal antibodies (mab’s), multispecifics, antibody-drug conjugates (ADCs), and other modalities...PrincipalFull time$175k - $225k
...ScholarRock on X and on LinkedIn. Summary of Position: Scholar Rock is seeking an accomplished and highly collaborative Principal Scientist, Biomarker Development, to provide scientific leadership for biomarker strategy and execution across preclinical programs in...PrincipalFull time- ...Description We are seeking a motivated and detail-oriented Associate Scientist to join our Preclinical Pharmacology team in Lexington, MA.... ...is a hands-on laboratory role supporting both in vivo and in vitro pharmacology studies , with a primary focus on immunology,...
$160k - $224k
The Role: Generate is seeking an accomplished Principal Scientist to lead Target Binding efforts within our Protein Analytics & Biophysics (PAB) department. This individual will provide scientific and strategic leadership for protein-protein interaction, target-binding,...PrincipalShift work$145k - $180k
...neuroimmunology and rare dermatology. Could you be our next Principal Scientist Translational Science Immunology The job is in our Waltham MA... ...AND ACCOUNTABILITIES: 1 Design and implement in vitro and ex vivo studies to investigate the mechanism of action of...PrincipalFull timeWork at office3 days per week- ...Description Job summary: Senior Associate Scientist, Cell Therapy PharmaEssentia... ...contribute to the development of novel immunotherapies for immunology and oncology. The successful... ...development and optimization in an in vitro pharmacology setting Knowledge of molecular...Flexible hours
- The MITRE Corporation in Bedford, Massachusetts, is seeking a Solution Lead Senior Principal (SLSP) to oversee 1-3 projects, driving them through the MITRE Innovation Lifecycle. The role requires strong project leadership and an entrepreneurial mindset to achieve disruptive...Principal
$112.8k - $169.2k
...therapeutics? Our Oligonucleotide Therapeutics Group (DDTech) at EMD Serono in Billerica, MA, is expanding, and we are looking for a Senior Scientist in Oligo Bioinformatics to lead the computational design and optimization of our next-generation siRNA and ASO pipelines. In...Flexible hours- Raytheon Technologies in Tewksbury, MA, seeks a Senior Principal Electrical Engineer with deep RF/Microwave system theory and AESA experience. You will design, validate, and test microwave components, subsystems, and CCA interfaces, supporting production activities. The...PrincipalRelocation
- ...Generate Biomedicines seeks a Principal Scientist to lead target binding efforts within the Protein Analytics & Biophysics department. This role combines technical expertise in biophysical assay development, technology innovation, cross-functional program leadership, and...Principal
- EMD Serono, Inc. in Billerica, MA, seeks a Senior Scientist in Oligonucleotide Bioinformatics to lead computational design and optimization of siRNA and ASO pipelines. You will sit at the intersection of computational biology, chemistry, and drug discovery, shaping programs...
- MBX Biosciences, Inc. seeks a Senior Scientist, Drug Substance to drive scalable, sustainable synthetic routes for MBX’s peptide drug substances and intermediates. You will support late-stage development, contribute to QbD initiatives, and help define control strategies...
- ...manufacturing processes. As a fast-growing company striving to make a difference every day, we are seeking a Senior Machine Learning Scientist to help build and maintain our cutting-edge machine learning pipeline and the critical tools and infrastructure that support it....Work experience placement
- EMD Serono, Inc. is seeking a Senior Scientist to advance our lipid nanoparticle (LNP) platform. You will design and execute in vivo studies to advance lead programs within the Discovery Pharmacology Team, reporting to the Head of Delivery Pharmacology. Extensive rodent...
- Cabot Corporation in Boston, MA seeks a Senior Scientist to lead a fast-moving Inkjet team. This role blends materials science with AI, ML, high-throughput experimentation, automation and advanced analytics to translate research into differentiated products and customer...
- EMD Serono is hiring a Senior Scientist to advance our lipid nanoparticle (LNP) platform. You will design and execute in vivo studies, lead rodent pharmacology experiments, and collaborate with cross-functional teams to push lead programs forward. The role requires a PhD...
- Cabot Corporation is seeking a Senior Scientist to lead our inkjet team, driving cross-functional projects that translate materials science into differentiated products and customer value. The role combines experimentation, data analysis, and practical leadership across...
- Scorpion Therapeutics is seeking a Senior Scientist in Sterile Oligonucleotide Drug Product Development in Bedford, MA (on-site, with ~10% travel to Waltham). The role focuses on developing and optimizing formulations and manufacturing processes for CNS and ocular oligonucleotide...
- E Ink Corporation is seeking a highly motivated Senior Polymer/Materials Scientist to conduct leading-edge materials research for next-generation electrophoretic display technologies. The candidate will design, formulate, fabricate, and characterize functional polymer films...
Do you want to receive more vacancies?
Subscribe and receive similar vacancies to Principal Scientist - In Vitro Immunotherapy. Be the first to apply!
- drug safety scientist Billerica, MA
- materials scientist Billerica, MA
- senior scientist Billerica, MA
- scientist biology Billerica, MA
- manufacturing scientist Billerica, MA
- water quality scientist Billerica, MA
- lab scientist Billerica, MA
- research scientist Billerica, MA
- deep learning scientist Billerica, MA
- machine learning research scientist Billerica, MA


