Downstream Scientist, Viral Vector

Required Skills & Experience Bachelor's degree in Molecular Biology, Biochemistry, Biotechnology, Genetics, Biological Sciences, or related field with 2+ years of industry experience Does not have a PhD, will not be considered Chromatography experience using the AKTA equipment Experience supporting high-throughput sample processing environments. Viral Vector experience (can be Lenti, AAV, or similar) TFF experience Small scale (R&D, pilot, discovery) experience (ideally 1L to 2L) Hands-on experience performing: DNA/RNA extraction and quantification ddPCR qPCR Molecular biology assays in a laboratory setting Nice to Have Skills & Experience: Experience working with lentiviral vector platforms. Background supporting cell and gene therapy programs. Job Description/Day to day: Janssen Pharmaceuticals is seeking a highly motivated Scientist to support analytical testing and characterization of viral vectors within a dynamic, high-throughput laboratory environment. This individual will play a key role in executing molecular biology assays that support viral vector development and characterization programs. The ideal candidate is a hands-on molecular biologist with strong experience in DNA/RNA extraction, ddPCR, qPCR, and molecular assay execution. Candidates with experience supporting lentiviral vector platforms and high-volume sample processing environments are especially encouraged to apply. This position offers the opportunity to work with cutting-edge technologies supporting cell and gene therapy programs while collaborating with cross-functional scientific teams. Responsibilities: Perform DNA and RNA extraction, purification, and quantification from a variety of sample types. Execute and analyze molecular assays including: Droplet Digital PCR (ddPCR) RT-ddPCR Quantitative PCR (qPCR) Viral genomic RNA (vgRNA) analysis Support viral vector characterization and analytical testing activities. Process large sample volumes in a high-throughput laboratory setting. Utilize laboratory automation tools including liquid handling systems when applicable. Troubleshoot assay performance issues and optimize experimental workflows. Interpret molecular data and generate accurate, high-quality documentation of results. Collaborate with scientists and cross-functional teams to support project goals and timelines. Maintain laboratory records and documentation in compliance with established procedures and quality standards. Contribute to continuous improvement efforts within laboratory operations. #J-18808-Ljbffr Insight Global