Sign up to access all features of our service.
  • Job search
  • Favorites
  • Create a CV
    New
  • Salaries
  • Subscriptions

Sr. Technical Program Manager, Infrastructure Rationalization

$145.9k - $234.2k

Moderna

Senior Technical Program Manager

Moderna is seeking a Senior Technical Program Manager to drive project and program management of infrastructure (cloud and on-prem) rationalization and AI-readiness initiatives at Moderna globally. We're looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.

Here's What You'll Do

  • Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting
  • Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process
  • Build processes, templates, and structure, or leverage existing ones as appropriate
  • Manage vendors, schedule, scope, and cost
  • Measure program success (or lack thereof) and risks using data and facts
  • Provide balanced risk remediation strategies and recommendations and drive risk mitigation
  • Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna
  • Provide clear, accurate, consistent, and timely communications
  • Advance good infrastructure and security practices and culture
  • Partner Collaboration work with Cloud Engineering, Systems Engineering, and AI Engineering, as well as Network Engineering, Identity and Access Management, Builder Tools & Platforms, IT, Cybersecurity, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner
  • Manage multiple initiatives:
  • Cloud modernization
  • Rationalize infrastructure platforms, tooling, and service models that underpin AI workloads.
  • Identify and eliminate redundant, unsupported, or non‑scalable infrastructure patterns that impede AI adoption.
  • Enable standardized, secure, and supportable "AI‑ready" infrastructure foundations that accelerate time‑to‑value while managing cost and risk.
  • Ensure infrastructure rationalization aligns with AI governance, data protection, and compliance requirements.
  • Define and track KPIs related to platform consolidation, cost optimization, risk reduction, and AI enablement readiness.
  • Lead and drive infrastructure service management improvements and process optimization initiatives, including infrastructure patch and vulnerability management.
  • Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes

Here's What You'll Need (Minimum Qualifications)

  • 8+ years of program management experience, preferably in infrastructure engineering
  • Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills
  • Technical background in infrastructure engineering, with a strong understanding of ITSM
  • Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations.
  • Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion
  • Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
  • Proven ability to operate in highly matrixed environments and influence without direct authority.

Here's What You'll Bring to the Table (Preferred Qualifications)

  • Strong understanding of cloud platforms (AWS, Azure)
  • Familiarity with infrastructure concepts: compute, storage, networking, containers, Kubernetes
  • Working knowledge of AI/ML infrastructure needs (GPUs, distributed training, data pipelines, MLOps)
  • Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
  • Deep familiarity with ITSM frameworks (e.g., ITIL)
  • Experience driving structured, process-driven infrastructure transformation initiatives.
  • Knowledge of security and compliance standards relevant to infrastructure operations.
  • Embrace a culture of continuous service improvement and service excellence
  • A desire to make an impact as part of a high-growth, transformational company
  • Experience with GxP environments and regulatory requirements

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That's why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

  • Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
  • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
  • Family planning benefits, including fertility, adoption, and surrogacy support
  • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
  • Savings and investment opportunities to help you plan for the future
  • Location-specific perks and extras

The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual's position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.

We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.

If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.

Our Working Model

As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Moderna is a smoke-free, alcohol-free, and drug-free work environment.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!

Moderna is an E-Verify Employer in the United States. We consider qualified applicants regardless of criminal histories, consistent with legal requirements.

Accommodations

We're focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at View email address on click.appcast.io.

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant's ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals

Vacancy posted 4 hours ago
Similar jobs that could be interesting for youBased on the Sr. Technical Program Manager, Infrastructure Rationalization in Cambridge, MA vacancy
  • $123.84k - $198.14k

     ...protecting life and making communities safer. We are seeking a Technical Program Manager to lead the delivery of complex, enterprise-grade SaaS...  ...delivering large-scale enterprise software deployments, infrastructure programs, or mission-critical application rollouts. ~... 
    Senior
    Work experience placement
    Remote work

    Axon

    Boston, MA
    15 hours ago
  • $125k - $167k

     ...Senior Technical Program Manager, Software Performance The Motional Technical Program Management team is seeking a talented TPM to support...  ...activities, specifically ensuring resources and infrastructure are available, and plans are coordinated and approved.... 
    Senior
    Work at office
    2 days per week
    3 days per week

    Venturefizz Product Management Community

    Boston, MA
    3 days ago
  • $170k - $250k

     ...Job Title: Senior Technical Program Manager Job Type: Full-time Job Location: Boston, MA Reports to: Vice President of Quantum...  ..., semiconductor, systems engineering, advanced computing infrastructure). ~ Experience in technical program management... 
    Senior
    Full time

    QuEra Computing, Inc.

    Boston, MA
    2 days ago
  • $124.9k - $146.1k

     ...looking for a with experience managing Corporate Payments projects,...  ...End-to-End Ownership: Drive technical implementation projects for...  ...planning sessions, ensuring program increments align with...  ...applications, endpoint security, infrastructure, networks, email security, and... 
    Senior
    Flexible hours

    WEX

    Boston, MA
    1 day ago
  • $131.25k - $210k

     ...highly motivated and experienced Program Manager, Adoption & Enablement to...  ...functionality, but also the technical concepts that underpin...  ...Approximately 50% Reports to : Sr. Director, RTO SaaS Delivery...  ...DVR/NVR systems and camera infrastructure Network connectivity,... 
    Senior
    Work experience placement

    Axon

    Boston, MA
    4 days ago
  • $145.9k - $234.2k

     ...needs. Define and document clear business and technical requirements, translating them into...  ...Product and Engineering teams. Lead end‑to‑end program planning and execution for complex cross‑functional initiatives, managing scope, schedules, dependencies, risks, and delivery... 
    Senior

    Moderna Therapeutics

    Cambridge, MA
    3 days ago
  • $109.2k - $223.4k

     ...Job Description Oracle Cloud Infrastructure (OCI) is scaling at an unprecedented pace to support the next generation of AI-driven workloads. We are seeking a Senior Principal Technical Program Manager (TPM) to lead engagement and AI capacity buildout for large-scale... 
    Senior
    Temporary work
    Flexible hours

    Oracle

    Boston, MA
    8 days ago
  • $145.9k - $234.2k

     ...Senior Technical Program Manager (TPM) Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management...  ...accountability, strong interpersonal skills, and infrastructure technology domain expertise. Here's What You'll Do... 
    Senior
    Work at office
    Work from home

    Moderna

    Cambridge, MA
    4 hours ago
  • $115.3k - $264.1k

     ...Job Description Manage the development and implementation process of a specific...  ...work of systems analysis and program staff, providing technical support and direction.Disclaimer:...  ...Only Oracle brings together the data, infrastructure, applications, and expertise to power... 
    Senior
    Temporary work
    Flexible hours

    Oracle

    Boston, MA
    1 day ago
  • $125k - $165k

     ...Program Manager (CapEx) At WHOOP, we're on a mission to unlock human performance. WHOOP...  ...As a CapEx Program Manager on the Technical Program Management (TPM) team at WHOOP...  ...investments into high-impact production infrastructure. You'll lead capital planning and execution... 
    Senior
    Full time

    Venturefizz Product Management Community

    Boston, MA
    3 days ago
  • $150k - $195k

     ...Senior Technical Program Manager WHOOP Boston, MA, US Job Type: Full-Time Function: Product Management Industry: Consumer...  ...to translate product, process, capacity, automation, and infrastructure needs into execution plans that balance innovation, cost,... 
    Senior
    Full time
    Contract work
    Work at office
    Relocation

    Softbank Investment Advisers

    Boston, MA
    3 days ago
  •  ...role and responsibilities About the Role As a Senior Technical Program Manager (TPM), you will be a key force-multiplier within...  ...working with or within an SRE, platform engineering, or infrastructure organization. IBM is committed to creating a diverse environment... 
    Senior
    Shift work

    IBM

    Boston, MA
    10 days ago
  • $120k - $180k

     ...Senior Technical Program Manager Do you want to change how the world creates? At Formlabs, we're building the tools that make it possible for anyone to bring their ideas to life, from cutting-edge products to life-saving medical devices. Our 3D printing technology... 
    Senior
    Full time
    Work at office
    Worldwide
    Overseas
    Flexible hours

    Formlabs

    Somerville, MA
    2 days ago
  • $113k - $194k

     ...based on the job level and your geographic work location. Relocation support is offered for eligible candidates. As a Sr. Technical Program Manager in our Personal Lines organization, you will own end-to-end delivery for significant, cross-functional capabilities... 
    Senior
    Full time
    Work at office
    Local area
    Relocation
    Relocation package
    Flexible hours

    American Family Insurance Agency Staff

    Boston, MA
    2 days ago
  •  ...you. Who You Are TetraScience is seeking an elite Technical Program Manager dedicated to a single, high-profile account in Cambridge...  .... Manage complex technical dependencies across cloud infrastructure, product development, data engineering pipelines, and AI... 
    Senior
    Work experience placement
    Immediate start

    TetraScience

    Boston, MA
    15 hours ago
  •  ...responsible for leading complex programs that provide the "fuel" for...  .... You aren't just managing timelines; you are architecting...  ...execution of high-priority technical programs for frontier AI labs...  ...environments, ensuring the infrastructure and human-feedback loops are... 
    Senior
    Local area
    Shift work

    Lilt

    Boston, MA
    3 days ago
  • Philo is looking for a Senior Technical Program Manager to lead the execution of multi-platform technical programs. The role involves working directly with product managers and engineering teams to ensure successful rollouts and effective communication across various domains... 
    Senior
    Full time
    Remote work

    Philo

    Cambridge, MA
    3 days ago
  • $150k - $215k

     ...Senior Technical Program Manager WHOOP is on a mission to unlock human performance and healthspan. Our Health Machine Learning team develops the algorithms and models that power health features used by millions of members. This role is critical to ensuring those efforts... 
    Senior
    Full time
    Work at office
    Relocation

    WHOOP

    Boston, MA
    1 day ago
  • $193k - $220.3k

    Senior Manager, Technical Program Manager AI / ML Are you interested in leading programs that deliver on critical business goals and build large scale...  ...the organization what a great TPM can achieve. Our TPM Sr. Managers have: Strong technical backgrounds (ideally building... 
    Senior
    Full time

    Capital One

    Cambridge, MA
    1 day ago
  • $146k - $182k

     ...processes that enable Sonos teams to deliver high-quality software efficiently and securely. We’re seeking an experienced Technical Program Manager to drive initiatives that improve developer experience, software quality, and operational excellence through better... 
    Full time
    Temporary work
    Work at office
    Immediate start
    Remote work
    Visa sponsorship
    Work visa
    3 days per week

    Sonos

    Boston, MA
    3 days ago
  • $192k - $306k

     ...Senior / Principal Technical Program Manager, Life Sciences AI Cambridge, MA USA; San Francisco, CA USA Your Impact at LILA Lila is building a platform where AI and automation co-evolve to solve the hardest problems in medicine. Within Life Science AI (LSAI)... 
    Senior
    Full time
    Work at office
    Local area
    Flexible hours

    Lila Sciences

    Cambridge, MA
    3 days ago
  • $115.3k - $264.1k

     ..., complex, cross-functional programs from concept through execution...  ...across engineering, product management, architecture, security,...  ...modernization programs. • Facilitate technical decision-making and...  ...principles, distributed systems, infrastructure, networking, security, and... 
    Senior
    Temporary work
    Flexible hours

    Oracle

    Boston, MA
    4 days ago
  • $109.2k - $223.4k

     ...Health Data Intelligence (HDI) is seeking a highly technical Senior Principal Technical Program Manager (IC5) to lead large-scale cloud transformation and...  ...architecture, system design, scalability, cloud infrastructure, and technical problem solving while driving execution... 
    Senior
    Temporary work
    Flexible hours

    Oracle

    Boston, MA
    4 days ago
  • Sonos LLC is searching for a Technical Program Manager to enhance developer experience and operational excellence in Boston. This hybrid role involves coordinating across engineering and platform teams to improve software quality and processes. The ideal candidate will... 

    Sonos LLC

    Boston, MA
    15 hours ago
  • A technology company is hiring an Engineering Program Manager in Somerville, MA to oversee the execution of software-enabled hardware programs. The role emphasizes planning, coordination, and delivery across engineering disciplines, ensuring alignment with customer requirements... 

    RISE® Robotics

    Somerville, MA
    1 day ago
  • $79.9k - $166.1k

     ...Job Description Oracle Cloud Infrastructure (OCI) is seeking an AI native, self-starter and detail-oriented Technical Program Manager to join our dynamic and fast-paced data analytics team. As a Technical Program Manager at Oracle OCI, you will play a crucial role... 
    Senior
    Temporary work
    Flexible hours

    Oracle

    Boston, MA
    1 day ago
  • $116k - $145k

    A leading cloud computing company is seeking a Senior Technical Program Manager. This role involves driving complex technical programs across engineering and product teams. The ideal candidate has over 5 years of program management experience in a technology environment... 
    Senior
    Remote job

    DigitalOcean

    Boston, MA
    15 hours ago
  • $119.6k - $215.4k

     ...Do you thrive on driving complex technical programs from vision to reality? Are you ready to orchestrate...  ...the delivery of cutting-edge AI infrastructure? Join the Akamai Inference Cloud...  ...best As a Senior Technical Program Manager, you will require technical understanding... 
    Senior
    Permanent employment
    Work experience placement
    Work at office
    Work from home
    Worldwide
    Flexible hours
    Shift work

    Akamai

    Cambridge, MA
    15 hours ago
  • Google Inc. is seeking a Technical Program Manager III for its Supply Chain and AI/ML Automation team. This role is essential for driving complex, multi-disciplinary projects that leverage innovations in AI. The ideal candidate will have a Bachelor's degree in a technical... 
    Senior

    Google Inc.

    Cambridge, MA
    1 day ago
  • $83.43k - $222.48k

    Stryker Corporation is seeking a Technical Program Manager in the United States, New Hampshire. The role involves leading large-scale programs that drive data strategy and ensuring alignment across various teams. The ideal candidate will thrive in complex environments and... 
    Senior
    Full time

    Stryker Corporation

    Boston, MA
    1 day ago

Do you want to receive more vacancies?

Subscribe and receive similar vacancies to Sr. Technical Program Manager, Infrastructure Rationalization. Be the first to apply!